Owen Tan
Owen Tan
Research fellow, Macquarie University
Verified email at mq.edu.au
TitleCited byYear
Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation
M Calao, EO Sekyere, HJ Cui, BB Cheung, WD Thomas, J Keating, ...
Oncogene 32 (31), 3616, 2013
532013
TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells
GM Marshall, JL Bell, J Koach, O Tan, P Kim, A Malyukova, W Thomas, ...
Oncogene 29 (46), 6172, 2010
392010
The estrogen-responsive B box protein (EBBP) restores retinoid sensitivity in retinoid-resistant cancer cells via effects on histone acetylation
A Raif, GM Marshall, JL Bell, J Koach, O Tan, C D’andreti, W Thomas, ...
Cancer letters 277 (1), 82-90, 2009
312009
Synthesis, characterization and anti-cancer activity of hydrazide derivatives incorporating a quinoline moiety
M Bingul, O Tan, C Gardner, S Sutton, G Arndt, G Marshall, B Cheung, ...
Molecules 21 (7), 916, 2016
292016
The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro
BB Cheung, J Koach, O Tan, P Kim, JL Bell, C D'andreti, S Sutton, ...
The Journal of pathology 226 (3), 451-462, 2012
272012
TRIM16 inhibits proliferation and migration through regulation of interferon beta 1 in melanoma cells
SK Sutton, J Koach, O Tan, B Liu, DR Carter, JS Wilmott, B Yosufi, ...
Oncotarget 5 (20), 10127, 2014
192014
High TDP43 expression is required for TRIM16-induced inhibition of cancer cell growth and correlated with good prognosis of neuroblastoma and breast cancer patients
PY Kim, O Tan, B Liu, T Trahair, T Liu, M Haber, MD Norris, GM Marshall, ...
Cancer letters 374 (2), 315-323, 2016
182016
TRIM16 overexpression induces apoptosis through activation of caspase-2 in cancer cells
PY Kim, AS Rahmanto, O Tan, MD Norris, M Haber, GM Marshall, ...
Apoptosis 18 (5), 639-651, 2013
182013
Application of Next‐Generation Sequencing (NGS) to improve cancer management: A review of the clinical effectiveness and cost‐effectiveness
O Tan, R Shrestha, M Cunich, DJ Schofield
Clinical Genetics, 2017
14*2017
Identification of plasma complement C3 as a potential biomarker for neuroblastoma using a quantitative proteomic approach
PY Kim, O Tan, SM Diakiw, D Carter, EO Sekerye, VC Wasinger, T Liu, ...
Journal of proteomics 96, 1-12, 2014
132014
Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma
BB Cheung, O Tan, J Koach, B Liu, MSY Shum, DR Carter, S Sutton, ...
Molecular oncology 9 (7), 1484-1500, 2015
82015
A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner
SK Sutton, DR Carter, P Kim, O Tan, GM Arndt, XD Zhang, J Baell, ...
Oncotarget 7 (32), 52166, 2016
62016
A Brief, Global History of Microsimulation Models in Health: Past Applications, Lessons Learned and Future Directions
DJ Schofield, MJB Zeppel, O Tan, S Lymer, MM Cunich, RN Shrestha
International Journal of Microsimulation 11 (1), 97-142, 2018
22018
Modelling the economic impact of next generation sequencing on childhood cancer management-a microsimulation approach
O Tan, D Schofield, R Shrestha
EUROPEAN JOURNAL OF HUMAN GENETICS 27, 1810-1810, 2019
2019
Telling the untold story: The economic and psychosocial impacts on families affected by intellectual disability
D Schofield, O Tan, R Shrestha, R Rajkumar, N Kasparian, M Rice, ...
EUROPEAN JOURNAL OF HUMAN GENETICS 27, 1391-1392, 2019
2019
Heterozygous loss of keratinocyte TRIM16 expression increases melanocytic cell lesions and lymph node metastasis
SK Sutton, BB Cheung, H Massudi, O Tan, J Koach, C Mayoh, DR Carter, ...
Journal of cancer research and clinical oncology 145 (9), 2241-2250, 2019
2019
TRIM16 inhibits cell growth through direct interaction and modulation of TDP43 protein stability in cancer cells
PY Kim, O Tan, T Trahair, T Liu, GM Marshall, BB Cheung
Cancer Research 74 (19 Supplement), 1403-1403, 2014
2014
TRIM16 is a prognostic marker for patients with lymph node metastatic melanoma.
BB Cheung, SK Sutton, O Tan, J Koach, B Liu, T Liu, RA Scolyer, ...
Cancer Research 73 (8 Supplement), 3876-3876, 2013
2013
Characterisation of a novel tumour suppressor TRIM16 in melanoma
S Sutton, O Tan, X Zhang, R Scolyer, G Marshall, B Cheung
Pigment Cell & Melanoma Research 25 (6), 2012
2012
786 Identification of Thymosin-beta-4-X as Indicator for Cytopathic Responses of Fenretinide and Vorinostat Combination Treatment
J Koach, O Tan, BB Cheung, GM Marshall
european journal of cancer 48, S187, 2012
2012
The system can't perform the operation now. Try again later.
Articles 1–20