|Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation|
M Calao, EO Sekyere, HJ Cui, BB Cheung, WD Thomas, J Keating, ...
Oncogene 32 (31), 3616, 2013
|TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells|
GM Marshall, JL Bell, J Koach, O Tan, P Kim, A Malyukova, W Thomas, ...
Oncogene 29 (46), 6172, 2010
|The estrogen-responsive B box protein (EBBP) restores retinoid sensitivity in retinoid-resistant cancer cells via effects on histone acetylation|
A Raif, GM Marshall, JL Bell, J Koach, O Tan, C D’andreti, W Thomas, ...
Cancer letters 277 (1), 82-90, 2009
|Synthesis, characterization and anti-cancer activity of hydrazide derivatives incorporating a quinoline moiety|
M Bingul, O Tan, C Gardner, S Sutton, G Arndt, G Marshall, B Cheung, ...
Molecules 21 (7), 916, 2016
|The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro|
BB Cheung, J Koach, O Tan, P Kim, JL Bell, C D'andreti, S Sutton, ...
The Journal of pathology 226 (3), 451-462, 2012
|TRIM16 inhibits proliferation and migration through regulation of interferon beta 1 in melanoma cells|
SK Sutton, J Koach, O Tan, B Liu, DR Carter, JS Wilmott, B Yosufi, ...
Oncotarget 5 (20), 10127, 2014
|High TDP43 expression is required for TRIM16-induced inhibition of cancer cell growth and correlated with good prognosis of neuroblastoma and breast cancer patients|
PY Kim, O Tan, B Liu, T Trahair, T Liu, M Haber, MD Norris, GM Marshall, ...
Cancer letters 374 (2), 315-323, 2016
|TRIM16 overexpression induces apoptosis through activation of caspase-2 in cancer cells|
PY Kim, AS Rahmanto, O Tan, MD Norris, M Haber, GM Marshall, ...
Apoptosis 18 (5), 639-651, 2013
|Application of Next‐Generation Sequencing (NGS) to improve cancer management: A review of the clinical effectiveness and cost‐effectiveness|
O Tan, R Shrestha, M Cunich, DJ Schofield
Clinical Genetics, 2017
|Identification of plasma complement C3 as a potential biomarker for neuroblastoma using a quantitative proteomic approach|
PY Kim, O Tan, SM Diakiw, D Carter, EO Sekerye, VC Wasinger, T Liu, ...
Journal of proteomics 96, 1-12, 2014
|Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma|
BB Cheung, O Tan, J Koach, B Liu, MSY Shum, DR Carter, S Sutton, ...
Molecular oncology 9 (7), 1484-1500, 2015
|A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner|
SK Sutton, DR Carter, P Kim, O Tan, GM Arndt, XD Zhang, J Baell, ...
Oncotarget 7 (32), 52166, 2016
|A Brief, Global History of Microsimulation Models in Health: Past Applications, Lessons Learned and Future Directions|
DJ Schofield, MJB Zeppel, O Tan, S Lymer, MM Cunich, RN Shrestha
International Journal of Microsimulation 11 (1), 97-142, 2018
|Modelling the economic impact of next generation sequencing on childhood cancer management-a microsimulation approach|
O Tan, D Schofield, R Shrestha
EUROPEAN JOURNAL OF HUMAN GENETICS 27, 1810-1810, 2019
|Telling the untold story: The economic and psychosocial impacts on families affected by intellectual disability|
D Schofield, O Tan, R Shrestha, R Rajkumar, N Kasparian, M Rice, ...
EUROPEAN JOURNAL OF HUMAN GENETICS 27, 1391-1392, 2019
|Heterozygous loss of keratinocyte TRIM16 expression increases melanocytic cell lesions and lymph node metastasis|
SK Sutton, BB Cheung, H Massudi, O Tan, J Koach, C Mayoh, DR Carter, ...
Journal of cancer research and clinical oncology 145 (9), 2241-2250, 2019
|TRIM16 inhibits cell growth through direct interaction and modulation of TDP43 protein stability in cancer cells|
PY Kim, O Tan, T Trahair, T Liu, GM Marshall, BB Cheung
Cancer Research 74 (19 Supplement), 1403-1403, 2014
|TRIM16 is a prognostic marker for patients with lymph node metastatic melanoma.|
BB Cheung, SK Sutton, O Tan, J Koach, B Liu, T Liu, RA Scolyer, ...
Cancer Research 73 (8 Supplement), 3876-3876, 2013
|Characterisation of a novel tumour suppressor TRIM16 in melanoma|
S Sutton, O Tan, X Zhang, R Scolyer, G Marshall, B Cheung
Pigment Cell & Melanoma Research 25 (6), 2012
|786 Identification of Thymosin-beta-4-X as Indicator for Cytopathic Responses of Fenretinide and Vorinostat Combination Treatment|
J Koach, O Tan, BB Cheung, GM Marshall
european journal of cancer 48, S187, 2012