Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans H Watanabe, N Chopra, D Laver, HS Hwang, SS Davies, DE Roach, ... Nature medicine 15 (4), 380-383, 2009 | 543 | 2009 |
Calsequestrin and the calcium release channel of skeletal and cardiac muscle NA Beard, DR Laver, AF Dulhunty Progress in biophysics and molecular biology 85 (1), 33-69, 2004 | 326 | 2004 |
Magnesium inhibition of ryanodine-receptor calcium channels: evidence for two independent mechanisms DR Laver, TM Baynes, AF Dulhunty The Journal of membrane biology 156 (3), 213-229, 1997 | 226 | 1997 |
Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass FA Hilliard, DS Steele, D Laver, Z Yang, SJ Le Marchand, N Chopra, ... Journal of molecular and cellular cardiology 48 (2), 293-301, 2010 | 213 | 2010 |
Ca2+ stores regulate ryanodine receptor Ca2+ release channels via luminal and cytosolic Ca2+ sites DR Laver Biophysical journal 92 (10), 3541-3555, 2007 | 198 | 2007 |
Cytoplasmic Ca 2+ inhibits the ryanodine receptor from cardiac muscle DR Laver, LD Roden, GP Ahern, KR Eager, PR Junankar, AF Dulhunty The Journal of membrane biology 147 (1), 7-22, 1995 | 189 | 1995 |
Calsequestrin is an inhibitor of skeletal muscle ryanodine receptor calcium release channels NA Beard, MM Sakowska, AF Dulhunty, DR Laver Biophysical journal 82 (1), 310-320, 2002 | 188 | 2002 |
Inhibition of Cardiac Ca2+ Release Channels (RyR2) Determines Efficacy of Class I Antiarrhythmic Drugs in Catecholaminergic Polymorphic Ventricular Tachycardia HS Hwang, C Hasdemir, D Laver, D Mehra, K Turhan, M Faggioni, H Yin, ... Circulation: Arrhythmia and Electrophysiology 4 (2), 128-135, 2011 | 123 | 2011 |
Regulation of ryanodine receptors by calsequestrin: effect of high luminal Ca2+ and phosphorylation NA Beard, MG Casarotto, L Wei, M Varsányi, DR Laver, AF Dulhunty Biophysical journal 88 (5), 3444-3454, 2005 | 122 | 2005 |
Reduced inhibitory effect of Mg2+ on ryanodine receptor-Ca2+ release channels in malignant hyperthermia DR Laver, VJ Owen, PR Junankar, NL Taske, AF Dulhunty, GD Lamb Biophysical journal 73 (4), 1913-1924, 1997 | 114 | 1997 |
Interactions between dihydropyridine receptors and ryanodine receptors in striated muscle AF Dulhunty, CS Haarmann, D Green, DR Laver, PG Board, ... Progress in biophysics and molecular biology 79 (1-3), 45-75, 2002 | 109 | 2002 |
Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants HS Hwang, FR Nitu, Y Yang, K Walweel, L Pereira, CN Johnson, ... Circulation research 114 (7), 1114-1124, 2014 | 103 | 2014 |
Activation and inhibition of skeletal RyR channels by a part of the skeletal DHPR II-III loop: effects of DHPR Ser687 and FKBP12 AF Dulhunty, DR Laver, EM Gallant, MG Casarotto, SM Pace, S Curtis Biophysical Journal 77 (1), 189-203, 1999 | 101 | 1999 |
Regulation of the calcium release channel from rabbit skeletal muscle by the nucleotides ATP, AMP, IMP and adenosine DR Laver, GKE Lenz, GD Lamb The Journal of physiology 537 (3), 763-778, 2001 | 96 | 2001 |
Luminal Ca2+–regulated Mg2+ Inhibition of Skeletal RyRs Reconstituted as Isolated Channels or Coupled Clusters DR Laver, ER O'Neill, GD Lamb The Journal of general physiology 124 (6), 741-758, 2004 | 95 | 2004 |
Control of sarcoplasmic reticulum Ca2+ release by stochastic RyR gating within a 3D model of the cardiac dyad and importance of induction decay for CICR termination MB Cannell, CHT Kong, MS Imtiaz, DR Laver Biophysical journal 104 (10), 2149-2159, 2013 | 93 | 2013 |
Termination of calcium-induced calcium release by induction decay: an emergent property of stochastic channel gating and molecular scale architecture DR Laver, CHT Kong, MS Imtiaz, MB Cannell Journal of molecular and cellular cardiology 54, 98-100, 2013 | 76 | 2013 |
Characteristics of two types of chloride channel in sarcoplasmic reticulum vesicles from rabbit skeletal muscle JI Kourie, DR Laver, PR Junankar, PW Gage, AF Dulhunty Biophysical journal 70 (1), 202-221, 1996 | 71 | 1996 |
Inactivation of Ca2+ release channels (ryanodine receptors RyR1 and RyR2) with rapid steps in [Ca2+] and voltage DR Laver, GD Lamb Biophysical Journal 74 (5), 2352-2364, 1998 | 70 | 1998 |
Generation and propagation of gastric slow waves DF Van Helden, DR Laver, J Holdsworth, MS Imtiaz Clinical and Experimental Pharmacology and Physiology 37 (4), 516-524, 2010 | 66 | 2010 |