David L Vaux
David L Vaux
Deputy Director, The Walter and Eliza Hall Institute
Verified email at
Cited by
Cited by
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
DL Vaux, S Cory, JM Adams
Nature 335 (6189), 440-442, 1988
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
AM Verhagen, PG Ekert, M Pakusch, J Silke, LM Connolly, GE Reid, ...
Cell 102 (1), 43-53, 2000
Cell death in development
DL Vaux, SJ Korsmeyer
Cell 96 (2), 245-254, 1999
The molecular biology of apoptosis.
DL Vaux, A Strasser
Proceedings of the National Academy of Sciences 93 (6), 2239-2244, 1996
IAP antagonists target cIAP1 to induce TNFα-dependent apoptosis
JE Vince, WWL Wong, N Khan, R Feltham, D Chau, AU Ahmed, ...
Cell 131 (4), 682-693, 2007
Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease.
A Strasser, S Whittingham, DL Vaux, ML Bath, JM Adams, S Cory, ...
Proceedings of the National Academy of Sciences 88 (19), 8661-8665, 1991
An evolutionary perspective on apoptosis
DL Vaux, G Haecker, A Strasser
Cell 76 (5), 777-779, 1994
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death
G Kroemer, WS El-Deiry, P Golstein, ME Peter, D Vaux, P Vandenabeele, ...
Cell death and differentiation 12 (12), 1463-1467, 2005
Error bars in experimental biology
G Cumming, F Fidler, DL Vaux
The Journal of cell biology 177 (1), 7-11, 2007
Toward an understanding of the molecular mechanisms of physiological cell death.
DL Vaux
Proceedings of the National Academy of Sciences 90 (3), 786-789, 1993
Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2
DL Vaux, IL Weissman, SK Kim
Science 258 (5090), 1955-1957, 1992
HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins
AM Verhagen, J Silke, PG Ekert, M Pakusch, H Kaufmann, LM Connolly, ...
Journal of Biological Chemistry 277 (1), 445-454, 2002
IAPs, RINGs and ubiquitylation
DL Vaux, J Silke
Nature reviews Molecular cell biology 6 (4), 287-297, 2005
Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype
AG Uren, L Wong, M Pakusch, KJ Fowler, FJ Burrows, DL Vaux, ...
Current Biology 10 (21), 1319-1328, 2000
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
VS Marsden, L O'Connor, LA O'Reilly, J Silke, D Metcalf, PG Ekert, ...
Nature 419 (6907), 634-637, 2002
Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.
AG Uren, M Pakusch, CJ Hawkins, KL Puls, DL Vaux
Proceedings of the National Academy of Sciences 93 (10), 4974-4978, 1996
Caspase inhibitors
PG Ekert, J Silke, DL Vaux
Cell Death & Differentiation 6 (11), 1081-1086, 1999
Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies
ARD Delbridge, S Grabow, A Strasser, DL Vaux
Nature Reviews Cancer 16 (2), 99-109, 2016
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
JA Rickard, JA O’Donnell, JM Evans, N Lalaoui, AR Poh, TW Rogers, ...
Cell 157 (5), 1175-1188, 2014
Apoptosis in the development and treatment of cancer
R Gerl, DL Vaux
Carcinogenesis 26 (2), 263-270, 2005
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