Aidan O'Brien
Aidan O'Brien
CSIRO, Australian National University
Verified email at csiro.au - Homepage
Title
Cited by
Cited by
Year
GT-Scan: identifying unique genomic targets
A O'Brien, TL Bailey
Bioinformatics, 2673-2675, 2014
882014
The current state and future of CRISPR-Cas9 gRNA design tools
LOW Wilson, AR O’Brien, DC Bauer
Frontiers in pharmacology 9, 749, 2018
492018
VariantSpark: population scale clustering of genotype information
AR O’Brien, NFW Saunders, Y Guo, FA Buske, RJ Scott, DC Bauer
BMC genomics 16 (1), 1-9, 2015
302015
High activity target-site identification using phenotypic independent CRISPR-Cas9 core functionality
LOW Wilson, D Reti, AR O'Brien, RA Dunne, DC Bauer
The CRISPR Journal 1 (2), 182-190, 2018
202018
Mutation analysis of MATR3 in Australian familial amyotrophic lateral sclerosis
JA Fifita, KL Williams, EP McCann, A O'Brien, DC Bauer, GA Nicholson, ...
Neurobiology of aging 36 (3), 1602.e1-1602.e2, 2015
152015
Artificial intelligence and machine learning in bioinformatics
K Lai, N Twine, A O’brien, Y Guo, D Bauer
Encyclopedia of Bioinformatics and Computational Biology: ABC of …, 2018
11*2018
Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation
CB Gurumurthy, AR O’Brien, RM Quadros, J Adams, P Alcaide, S Ayabe, ...
Genome biology 20 (1), 1-14, 2019
92019
Unlocking HDR-mediated nucleotide editing by identifying high-efficiency target sites using machine learning
AR o’Brien, LOW Wilson, G Burgio, DC Bauer
Scientific reports 9 (1), 1-10, 2019
72019
VariantSpark, A Random Forest Machine Learning Implementation for Ultra High Dimensional Data
A Bayat, P Szul, AR O’Brien, R Dunne, OJ Luo, Y Jain, B Hosking, ...
bioRxiv, 702902, 2019
22019
Domain-specific introduction to machine learning terminology, pitfalls and opportunities in CRISPR-based gene editing
AR O’Brien, G Burgio, DC Bauer
Briefings in Bioinformatics, 2020
12020
VariantSpark: Cloud-based machine learning for association study of complex phenotype and large-scale genomic data
A Bayat, P Szul, AR O’Brien, R Dunne, B Hosking, Y Jain, C Hosking, ...
GigaScience 9 (8), giaa077, 2020
2020
Breaking the curse of dimensionality for machine learning on genomic data
A O’Brien, P Szul, O Luo, A George, R Dunne, D Bauer
IJCAI 2017, 2017
2017
Defining and evaluating an operational definition of potentially preventable hospital readmission
A O'Brien
Sydney, Australia: Macquarie University, 2017
2017
VariantSpark: Applying Spark-based machine learning methods to genomic information
AR O'Brien, DC Bauer
BigData 2015, 2015
2015
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Articles 1–14