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Gabrielle Watson
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Modulation of innate and adaptive immunity by cytomegaloviruses
R Berry, GM Watson, S Jonjic, MA Degli-Esposti, J Rossjohn
Nature reviews immunology 20 (2), 113-127, 2020
1002020
A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44
A Niehrs, WF Garcia-Beltran, PJ Norman, GM Watson, A Hölzemer, ...
Nature immunology 20 (9), 1129-1137, 2019
722019
Structural basis for CD96 immune receptor recognition of nectin-like protein-5, CD155
FA Deuss, GM Watson, Z Fu, J Rossjohn, R Berry
Structure 27 (2), 219-228. e3, 2019
472019
Discovery, development, and cellular delivery of potent and selective bicyclic peptide inhibitors of Grb7 cancer target
GM Watson, K Kulkarni, J Sang, X Ma, MJ Gunzburg, P Perlmutter, ...
Journal of Medicinal Chemistry 60 (22), 9349-9359, 2017
292017
Cyclic peptides incorporating phosphotyrosine mimetics as potent and specific inhibitors of the Grb7 breast cancer target
GM Watson, MJ Gunzburg, ND Ambaye, WAH Lucas, DA Traore, ...
Journal of medicinal chemistry 58 (19), 7707-7718, 2015
252015
Shortened penetratin cell-penetrating peptide is insufficient for cytosolic delivery of a Grb7 targeting peptide
GM Watson, K Kulkarni, R Brandt, MP Del Borgo, MI Aguilar, JA Wilce
ACS omega 2 (2), 670-677, 2017
232017
Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7
MJ Gunzburg, K Kulkarni, GM Watson, ND Ambaye, MP Del Borgo, ...
Scientific Reports 6 (1), 27060, 2016
222016
Structural basis for the recognition of nectin-like protein-5 by the human-activating immune receptor, DNAM-1
FA Deuss, GM Watson, KJ Goodall, I Leece, S Chatterjee, Z Fu, ...
Journal of Biological Chemistry 294 (33), 12534-12546, 2019
142019
A pocket guide on how to structure SARS-CoV-2 drugs and therapies
DR Littler, BJ MacLachlan, GM Watson, JP Vivian, BS Gully
Biochemical Society Transactions 48 (6), 2625-2641, 2020
132020
Direct interaction between calmodulin and the Grb7 RA-PH domain
GM Watson, JA Wilce
International Journal of Molecular Sciences 21 (4), 1336, 2020
82020
Evaluation of cyclic peptide inhibitors of the Grb7 breast Cancer target: small change in cargo results in large change in cellular activity
J Sang, K Kulkarni, GM Watson, X Ma, DJ Craik, ST Henriques, AG Poth, ...
Molecules 24 (20), 3739, 2019
82019
Insight into the selectivity of the G7-18NATE inhibitor peptide for the Grb7-SH2 domain target
GM Watson, WAH Lucas, MJ Gunzburg, JA Wilce
Frontiers in Molecular Biosciences 4, 64, 2017
82017
Preparation and cellular uptake of bicyclic‐peptide cargo clicked to cell penetrating peptides
K Kulkarni, GM Watson, J Sang, JA Wilce
Peptide Science 110 (3), e24037, 2018
42018
Enhancing the bioactivity of bicyclic peptides targeted to Grb7-SH2 by restoring cell permeability
NP Sturre, RN Colson, N Shah, GM Watson, X Yang, MCJ Wilce, JT Price, ...
Biomedicines 10 (5), 1145, 2022
22022
Aryl amino acetamides prevent the development of Plasmodium falciparum rings via inhibition of the lipid transfer protein PfSTART1
MG Dans, C Boulet, GM Watson, W Nguyen, JM Dziekan, C Evelyn, ...
bioRxiv, 2023.11. 02.565411, 2023
12023
Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 protein
W Nguyen, C Boulet, MG Dans, K Loi, KE Jarman, GM Watson, WH Tham, ...
European Journal of Medicinal Chemistry 270, 116354, 2024
2024
Diverse cytomegalovirus US11 antagonism and MHC-A evasion strategies reveal a tit-for-tat coevolutionary arms race in hominids
C Zimmermann, GM Watson, L Bauersfeld, R Berry, B Ciblis, H Lan, ...
Proceedings of the National Academy of Sciences 121 (9), e2315985121, 2024
2024
Using Surface Plasmon Resonance to Study SH2 Domain–Peptide Interactions
GM Watson, MJ Gunzburg, JA Wilce
SH2 Domains: Functional Modules and Evolving Tools in Biology, 199-210, 2023
2023
The natural cytotoxicity receptor NKp44 interacts with a subset of HLA-DP molecules
A Niehrs, WF Garcia-Beltran, PJ Norman, GM Watson, A Hoelzemer, ...
EUROPEAN JOURNAL OF IMMUNOLOGY 49, 20-21, 2019
2019
Developing potent and specific inhibitors of the Grb7 breast cancer target using phosphotyrosine mimetics and bicyclic peptides
G Watson, M Gunzburg, K Kulkarni, K Cergol, R Payne, P Perlmutter, ...
PROTEIN SCIENCE 25, 124-125, 2016
2016
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Articles 1–20