A multifunctional serine protease primes the malaria parasite for red blood cell invasion K Koussis, C Withers‐Martinez, S Yeoh, M Child, F Hackett, E Knuepfer, ... The EMBO journal 28 (6), 725-735, 2009 | 213 | 2009 |
A small-molecule antivirulence agent for treating Clostridium difficile infection KO Bender, M Garland, JA Ferreyra, AJ Hryckowian, MA Child, AW Puri, ... Science translational medicine 7 (306), 306ra148-306ra148, 2015 | 134 | 2015 |
Rapid evolution of blood-brain-barrier-penetrating AAV capsids by RNA-driven biopanning M Nonnenmacher, W Wang, MA Child, XQ Ren, C Huang, AZ Ren, ... Molecular Therapy-Methods & Clinical Development 20, 366-378, 2021 | 100 | 2021 |
Global analysis of palmitoylated proteins in Toxoplasma gondii IT Foe, MA Child, JD Majmudar, S Krishnamurthy, WA van der Linden, ... Cell host & microbe 18 (4), 501-511, 2015 | 84 | 2015 |
Activity-and reactivity-based proteomics: Recent technological advances and applications in drug discovery HJ Benns, CJ Wincott, EW Tate, MA Child Current Opinion in Chemical Biology 60, 20-29, 2021 | 82 | 2021 |
Proteases as regulators of pathogenesis: examples from the Apicomplexa H Li, MA Child, M Bogyo Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1824 (1), 177-185, 2012 | 79 | 2012 |
The Calcium-Dependent Protein Kinase 3 of Toxoplasma Influences Basal Calcium Levels and Functions beyond Egress as Revealed by Quantitative … M Treeck, JL Sanders, RY Gaji, KA LaFavers, MA Child, G Arrizabalaga, ... PLoS pathogens 10 (6), e1004197, 2014 | 69 | 2014 |
Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion MA Child, CI Hall, JR Beck, LO Ofori, VE Albrow, M Garland, PW Bowyer, ... Nature chemical biology 9 (10), 651-656, 2013 | 69 | 2013 |
Elucidating the interplay between IgG-Fc valency and FcγR activation for the design of immune complex inhibitors DF Ortiz, JC Lansing, L Rutitzky, E Kurtagic, T Prod’homme, A Choudhury, ... Science translational medicine 8 (365), 365ra158-365ra158, 2016 | 68 | 2016 |
Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion CI Hall, ML Reese, E Weerapana, MA Child, PW Bowyer, VE Albrow, ... Proceedings of the National Academy of Sciences 108 (26), 10568-10573, 2011 | 67 | 2011 |
Regulated maturation of malaria merozoite surface protein‐1 is essential for parasite growth MA Child, C Epp, H Bujard, MJ Blackman Molecular microbiology 78 (1), 187-202, 2010 | 58 | 2010 |
Development of an activity-based probe for acyl-protein thioesterases M Garland, CJ Schulze, IT Foe, WA van der Linden, MA Child, M Bogyo PloS one 13 (1), e0190255, 2018 | 20 | 2018 |
Molecular determinants for subcellular trafficking of the malarial sheddase PfSUB2 MA Child, PK Harris, CR Collins, C Withers‐Martinez, S Yeoh, ... Traffic 14 (10), 1053-1064, 2013 | 18 | 2013 |
CRISPR-based oligo recombineering prioritizes apicomplexan cysteines for drug discovery HJ Benns, M Storch, JA Falco, FR Fisher, F Tamaki, E Alves, CJ Wincott, ... Nature Microbiology 7 (11), 1891-1905, 2022 | 16 | 2022 |
Toxoplasma DJ-1 regulates organelle secretion by a direct interaction with calcium-dependent protein kinase 1 MA Child, M Garland, I Foe, P Madzelan, M Treeck, WA Van Der Linden, ... MBio 8 (1), 10.1128/mbio. 02189-16, 2017 | 14 | 2017 |
Activity-based protein profiling for the study of parasite biology HJ Benns, EW Tate, MA Child Activity-Based Protein Profiling, 155-174, 2019 | 12 | 2019 |
Design and synthesis of activity-based probes and inhibitors for bleomycin hydrolase WA van der Linden, E Segal, MA Child, A Byzia, M Drąg, M Bogyo Chemistry & biology 22 (8), 995-1001, 2015 | 11 | 2015 |
An Extracellular Redox Signal Triggers Calcium Release and Impacts the Asexual Development of Toxoplasma gondii E Alves, HJ Benns, L Magnus, C Dominicus, T Dobai, J Blight, CJ Wincott, ... Frontiers in Cellular and Infection Microbiology 11, 728425, 2021 | 10 | 2021 |
Cellular barcoding of protozoan pathogens reveals the within-host population dynamics of Toxoplasma gondii host colonization CJ Wincott, G Sritharan, HJ Benns, D May, C Gilabert-Carbajo, M Bunyan, ... Cell Reports Methods 2 (8), 2022 | 9 | 2022 |
Malaria parasite evades mosquito immunity by glutaminyl cyclase–mediated posttranslational protein modification SK Kolli, A Molina-Cruz, T Araki, FJA Geurten, J Ramesar, ... Proceedings of the National Academy of Sciences 119 (35), e2209729119, 2022 | 7 | 2022 |