| Gastrointestinal-resident, shape-changing microdevices extend drug release in vivo A Ghosh, L Li, L Xu, RP Dash, N Gupta, J Lam, Q Jin, V Akshintala, ... Science advances 6 (44), eabb4133, 2020 | 80 | 2020 |
| Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug R Rais, KM Lemberg, L Tenora, ML Arwood, A Pal, J Alt, Y Wu, J Lam, ... Science advances 8 (46), eabq5925, 2022 | 39 | 2022 |
| Tumor-Targeted Delivery of 6-Diazo-5-oxo-l-norleucine (DON) Using Substituted Acetylated Lysine Prodrugs L Tenora, J Alt, RP Dash, AJ Gadiano, K Novotna, V Veeravalli, J Lam, ... Journal of medicinal chemistry 62 (7), 3524-3538, 2019 | 37 | 2019 |
| Synthesis of C-acyl furanosides via the cross-coupling of glycosyl esters with carboxylic acids Y Wei, J Lam, T Diao Chemical Science 12 (34), 11414-11419, 2021 | 35 | 2021 |
| Novel human neutral sphingomyelinase 2 inhibitors as potential therapeutics for Alzheimer’s disease M Šála, KR Hollinger, AG Thomas, RP Dash, C Tallon, V Veeravalli, ... Journal of medicinal chemistry 63 (11), 6028-6056, 2020 | 35 | 2020 |
| Investigation of novel primary and secondary pharmacophores and 3-substitution in the linking chain of a series of highly selective and bitopic dopamine D3 receptor antagonists … AB Shaik, V Kumar, A Bonifazi, AM Guerrero, SL Cemaj, A Gadiano, ... Journal of medicinal chemistry 62 (20), 9061-9077, 2019 | 32 | 2019 |
| The Significance of Chirality in Drug Design and Synthesis of Bitopic Ligands as D3 Receptor (D3R) Selective Agonists FO Battiti, SL Cemaj, AM Guerrero, AB Shaik, J Lam, R Rais, BS Slusher, ... Journal of medicinal chemistry 62 (13), 6287-6314, 2019 | 30 | 2019 |
| Structure–activity relationships for a series of (bis (4-fluorophenyl) methyl) sulfinyl alkyl alicyclic amines at the dopamine transporter: functionalizing the terminal … RD Slack, TC Ku, J Cao, JLB Giancola, A Bonifazi, CJ Loland, A Gadiano, ... Journal of medicinal chemistry 63 (5), 2343-2357, 2019 | 20 | 2019 |
| The novel glutamine antagonist prodrug JHU395 has antitumor activity in malignant peripheral nerve sheath tumor KM Lemberg, L Zhao, Y Wu, V Veeravalli, J Alt, JMH Aguilar, RP Dash, ... Molecular cancer therapeutics 19 (2), 397-408, 2020 | 18 | 2020 |
| Enhanced oral bioavailability of 2-(phosphonomethyl)-pentanedioic acid (2-PMPA) from its (5-methyl-2-oxo-1, 3-dioxol-4-yl) methyl (ODOL)-based prodrugs RP Dash, T Tichý, V Veeravalli, J Lam, J Alt, Y Wu, L Tenora, P Majer, ... Molecular pharmaceutics 16 (10), 4292-4301, 2019 | 14 | 2019 |
| A highly D3R-selective and efficacious partial agonist (S)-ABS01-113 compared to its D3R-selective antagonist enantiomer (R)-ABS01-113 as potential … E Galaj, GH Bi, B Klein, B Hempel, AB Shaik, ES Gogarnoiu, J Friedman, ... Neuropsychopharmacology 47 (13), 2309-2318, 2022 | 13 | 2022 |
| Structure-activity relationships for a series of (Bis (4-fluorophenyl) methyl) sulfinylethyl-aminopiperidines and-piperidine amines at the dopamine transporter: Bioisosteric … JLB Giancola, A Bonifazi, J Cao, T Ku, AJ Haraczy, J Lam, R Rais, ... European journal of medicinal chemistry 208, 112674, 2020 | 13 | 2020 |
| The effects of the dopamine transporter ligands JJC8-088 and JJC8-091 on cocaine versus food choice in rhesus monkeys O Rahimi, J Cao, J Lam, SR Childers, R Rais, LJ Porrino, AH Newman, ... Journal of Pharmacology and Experimental Therapeutics 384 (3), 372-381, 2023 | 6 | 2023 |
| Modifications to 1-(4-(2-Bis (4-fluorophenyl) methyl) sulfinyl) alkyl Alicyclic Amines That Improve Metabolic Stability and Retain an Atypical DAT Inhibitor Profile AV Okorom, GA Camacho-Hernandez, K Salomon, KH Lee, TC Ku, J Cao, ... Journal of medicinal chemistry 67 (1), 709-727, 2023 | 3 | 2023 |
| Model studies towards prodrugs of the glutamine antagonist 6-diazo-5-oxo-l-norleucine (DON) containing a diazo precursor RD Gao, N Hin, E Prchalová, A Pal, J Lam, R Rais, BS Slusher, ... Bioorganic & medicinal chemistry letters 50, 128321, 2021 | 2 | 2021 |
| Synthesis and neoglycosylation with stereo-diverse 2-amino free-reducing sugars A Scharnow, J Lam, V Huang, I Rocroi, C Rojas ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
| Method development for copper-catalyzed synthesis and glycodiversification reactions of 2-amino sugar building blocks J Lam, M Miller, A Oviatt, A Scharnow, R Starr, C Rojas ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
