Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation JP Brennan, R Southworth, RA Medina, SM Davidson, MR Duchen, ... Cardiovascular research 72 (2), 313-321, 2006 | 275 | 2006 |
Targeting hexokinase II to mitochondria to modulate energy metabolism and reduce ischaemia‐reperfusion injury in heart R Nederlof, O Eerbeek, MW Hollmann, R Southworth, CJ Zuurbier British journal of pharmacology 171 (8), 2067-2079, 2014 | 113 | 2014 |
Disruption of hexokinase II–mitochondrial binding blocks ischemic preconditioning and causes rapid cardiac necrosis KMA Smeele, R Southworth, R Wu, C Xie, R Nederlof, A Warley, ... Circulation research 108 (10), 1165-1169, 2011 | 95 | 2011 |
A reevaluation of the roles of hexokinase I and II in the heart R Southworth, KAB Davey, A Warley, PB Garlick American journal of physiology-heart and circulatory physiology 292 (1 …, 2007 | 75 | 2007 |
Renal vascular inflammation induced by Western diet in ApoE-null mice quantified by 19F NMR of VCAM-1 targeted nanobeacons R Southworth, M Kaneda, J Chen, L Zhang, H Zhang, X Yang, R Razavi, ... Nanomedicine: Nanotechnology, Biology and Medicine 5 (3), 359-367, 2009 | 73 | 2009 |
PET imaging of cardiac hypoxia: opportunities and challenges MG Handley, RA Medina, E Nagel, PJ Blower, R Southworth Journal of molecular and cellular cardiology 51 (5), 640-650, 2011 | 68 | 2011 |
Immunogold labeling study of the distribution of GLUT-1 and GLUT-4 in cardiac tissue following stimulation by insulin or ischemia KAB Davey, PB Garlick, A Warley, R Southworth American Journal of Physiology-Heart and Circulatory Physiology 292 (4 …, 2007 | 66 | 2007 |
An isolated perfused pig heart model for the development, validation and translation of novel cardiovascular magnetic resonance techniques A Schuster, I Grünwald, A Chiribiri, R Southworth, M Ishida, G Hay, ... Journal of Cardiovascular Magnetic Resonance 12 (1), 53, 2010 | 64 | 2010 |
Tissue‐specific differences in 2‐fluoro‐2‐deoxyglucose metabolism beyond FDG‐6‐P: a 19F NMR spectroscopy study in the rat R Southworth, CR Parry, HG Parkes, RA Medina, PB Garlick NMR in Biomedicine: An International Journal Devoted to the Development and …, 2003 | 61 | 2003 |
Monitoring of in vivo function of superparamagnetic iron oxide labelled murine dendritic cells during anti-tumour vaccination R Tavare, P Sagoo, G Varama, Y Tanriver, A Warely, SS Diebold, ... PloS one 6 (5), e19662, 2011 | 52 | 2011 |
Cardiac hypoxia imaging: second-generation analogues of 64Cu-ATSM MG Handley, RA Medina, E Mariotti, GD Kenny, KP Shaw, R Yan, ... Journal of Nuclear Medicine 55 (3), 488-494, 2014 | 50 | 2014 |
64Cu-CTS: a promising radiopharmaceutical for the identification of low-grade cardiac hypoxia by PET RA Medina, E Mariotti, D Pavlovic, KP Shaw, TR Eykyn, PJ Blower, ... Journal of Nuclear Medicine 56 (6), 921-926, 2015 | 32 | 2015 |
Multiple quantum filtered 23Na NMR in the Langendorff perfused mouse heart: Ratio of triple/double quantum filtered signals correlates with [Na] i TR Eykyn, D Aksentijević, KL Aughton, R Southworth, W Fuller, ... Journal of Molecular and Cellular Cardiology 86, 95-101, 2015 | 31 | 2015 |
Detection of anthracycline-induced cardiotoxicity using perfusion-corrected 99mTc sestamibi SPECT ZM Safee, F Baark, ECT Waters, M Veronese, VR Pell, JE Clark, F Mota, ... Scientific Reports 9 (1), 216, 2019 | 29 | 2019 |
Imaging of chemotherapy-induced acute cardiotoxicity with 18F-labeled lipophilic cations SP McCluskey, A Haslop, C Coello, RN Gunn, EW Tate, R Southworth, ... Journal of Nuclear Medicine 60 (12), 1750-1756, 2019 | 28 | 2019 |
Lactate-induced translocation of GLUT1 and GLUT4 is not mediated by the phosphatidylinositol-3-kinase pathway in the rat heart RA Medina, R Southworth, W Fuller, PB Garlick Basic research in cardiology 97, 168-176, 2002 | 27 | 2002 |
Hexokinase-mitochondrial interaction in cardiac tissue: implications for cardiac glucose uptake, the 18FDG lumped constant and cardiac protection R Southworth Journal of bioenergetics and biomembranes 41, 187-193, 2009 | 22 | 2009 |
Modeling non‐linear kinetics of hyperpolarized [1‐13C] pyruvate in the crystalloid‐perfused rat heart E Mariotti, MR Orton, O Eerbeek, JF Ashruf, CJ Zuurbier, R Southworth, ... NMR in Biomedicine 29 (4), 377-386, 2016 | 21 | 2016 |
Dissociation of glucose tracer uptake and glucose transporter distribution in the regionally ischaemic isolated rat heart: application of a new autoradiographic technique R Southworth, JL Dearling, RA Medina, AA Flynn, BR Pedley, PB Garlick European journal of nuclear medicine and molecular imaging 29, 1334-1341, 2002 | 21 | 2002 |
Developmental differences in superoxide production in isolated guinea-pig hearts during reperfusion R Southworth, MJ Shattock, DJ Hearse, FJ Kelly Journal of molecular and cellular cardiology 30 (7), 1391-1399, 1998 | 21 | 1998 |