Dr Alessia Belgi
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Use of a temporary “solubilizing” peptide tag for the Fmoc solid-phase synthesis of human insulin glargine via use of regioselective disulfide bond formation
MA Hossain, A Belgi, F Lin, S Zhang, F Shabanpoor, L Chan, C Belyea, ...
Bioconjugate chemistry 20 (7), 1390-1396, 2009
Minimization of human relaxin-3 leading to high-affinity analogues with increased selectivity for relaxin-family peptide 3 receptor (RXFP3) over RXFP1
F Shabanpoor, M Akhter Hossain, PJ Ryan, A Belgi, S Layfield, M Kocan, ...
Journal of medicinal chemistry 55 (4), 1671-1681, 2012
Dicarba α-Conotoxin Vc1.1 Analogues with Differential Selectivity for Nicotinic Acetylcholine and GABAB Receptors
BJ Van Lierop, SD Robinson, SN Kompella, A Belgi, JR McArthur, A Hung, ...
ACS chemical biology 8 (8), 1815-1821, 2013
Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets
S Chhabra, A Belgi, P Bartels, BJ van Lierop, SD Robinson, SN Kompella, ...
Journal of medicinal chemistry 57 (23), 9933-9944, 2014
Structure and function relationship of murine insulin-like peptide 5 (INSL5): free C-terminus is essential for RXFP4 receptor binding and activation
A Belgi, MA Hossain, F Shabanpoor, L Chan, S Zhang, RAD Bathgate, ...
Biochemistry 50 (39), 8352-8361, 2011
Site-specific conjugation of a lanthanide chelator and its effects on the chemical synthesis and receptor binding affinity of human relaxin-2 hormone
F Shabanpoor, RAD Bathgate, A Belgi, LJ Chan, VB Nair, JD Wade, ...
Biochemical and biophysical research communications 420 (2), 253-256, 2012
The chemical synthesis of insulin: from the past to the present
A Belgi, M Akhter Hossain, G W Tregear, J D Wade
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Formerly …, 2011
Minimum active structure of insulin-like peptide 5
A Belgi, RAD Bathgate, M Kocan, N Patil, S Zhang, GW Tregear, JD Wade, ...
Journal of Medicinal Chemistry 56 (23), 9509-9516, 2013
A naturally occurring peptide with an elementary single disulfide-directed β-hairpin fold
SD Robinson, S Chhabra, A Belgi, B Chittoor, H Safavi-Hemami, ...
Structure 24 (2), 293-299, 2016
Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity
B Van Lierop, SC Ong, A Belgi, C Delaine, S Andrikopoulos, NL Haworth, ...
Scientific reports 7 (1), 1-14, 2017
Preliminary structure–function relationship studies on insulin-like peptide 5 (INSL5)
A Belgi, RAD Bathgate, GW Tregear, JD Wade, MA Hossain
International Journal of Peptide Research and Therapeutics 19 (1), 71-79, 2013
Structure and activity of contryphan-Vc2: Importance of the D-amino acid residue
SB Drane, SD Robinson, CA MacRaild, S Chhabra, B Chittoor, ...
Toxicon 129, 113-122, 2017
Probing the correlation between insulin activity and structural stability through introduction of the rigid A6–A11 bond
SC Ong, A Belgi, B Van Lierop, C Delaine, S Andrikopoulos, CA MacRaild, ...
Journal of Biological Chemistry 293 (30), 11928-11943, 2018
Dicarba modification of α-conotoxin RgIA conferring selectivity towards α9α10 nicotinic acetylcholine receptors
SN Kompella, BJ van Lierop, SD Robinson, A Belgi, B Callaghan, A Hung, ...
Biochemical Pharmacology 8 (86), 1230, 2013
Solid phase synthesis of an analogue of insulin, A0: R glargine, that exhibits decreased mitogenic activity
SY Kwak, BE Forbes, YS Lee, A Belgi, JD Wade, MA Hossain
International Journal of Peptide Research and Therapeutics 16 (3), 153-158, 2010
Novel insulin analogues with improved therapeutic benefits: dicarba insulin analogues exhibit reduced mitogenic potential
SC Ong, A Belgi, B van Lierop, J Menting, M Lawrence, S Andrikopoulos, ...
DIABETOLOGIA 59, S241-S241, 2016
J Wade, M Hossain, S Zhang, F Lin, F Shabanpoor, A Belgi, L Chan, ...
BIOPOLYMERS 92 (4), 308-308, 2009
A. Belgi 2, B. Callaghan, A. Hung, CA MacRaild 3, RS Norton 3, AJ Robinson 2, DJ Adams Health Innovations Research Institute, RMIT University, Melbourne, Australia 2 School of …
SN Kompella, BJ van Lierop
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