Bispecific antibodies and antibody–drug conjugates (ADCs) bridging HER2 and prolactin receptor improve efficacy of HER2 ADCs J Andreev, N Thambi, AE Perez Bay, F Delfino, J Martin, MP Kelly, ... Molecular cancer therapeutics 16 (4), 681-693, 2017 | 138 | 2017 |
Antibody-targeted NY-ESO-1 to mannose receptor or DEC-205 in vitro elicits dual human CD8+ and CD4+ T cell responses with broad antigen specificity T Tsuji, J Matsuzaki, MP Kelly, V Ramakrishna, L Vitale, LZ He, T Keler, ... The Journal of Immunology 186 (2), 1218-1227, 2011 | 137 | 2011 |
Arginine deiminase PEG20 inhibits growth of small cell lung cancers lacking expression of argininosuccinate synthetase MP Kelly, AA Jungbluth, BW Wu, J Bomalaski, LJ Old, G Ritter British journal of cancer 106 (2), 324-332, 2012 | 127 | 2012 |
A gene differentially expressed in the kidney of the spontaneously hypertensive rat cosegregates with increased blood pressure. NJ Samani, D Lodwick, M Vincent, C Dubay, MA Kaiser, MP Kelly, M Lo, ... The Journal of clinical investigation 92 (2), 1099-1103, 1993 | 123 | 1993 |
A Mucin 16 bispecific T cell–engaging antibody for the treatment of ovarian cancer A Crawford, L Haber, MP Kelly, K Vazzana, L Canova, P Ram, A Pawashe, ... Science translational medicine 11 (497), eaau7534, 2019 | 102 | 2019 |
Enhanced efficacy of radioimmunotherapy with 90Y-CHX-A ″-DTPA-hu3S193 by inhibition of epidermal growth factor receptor (EGFR) signaling with EGFR tyrosine kinase inhibitor AG1478 FT Lee, AJ Mountain, MP Kelly, C Hall, A Rigopoulos, TG Johns, ... Clinical cancer research 11 (19), 7080s-7086s, 2005 | 100 | 2005 |
Therapeutic efficacy of 177Lu‐CHX‐A ″‐DTPA‐hu3S193 radioimmunotherapy in prostate cancer is enhanced by EGFR inhibition or docetaxel chemotherapy MP Kelly, ST Lee, FT Lee, FE Smyth, ID Davis, MW Brechbiel, AM Scott The Prostate 69 (1), 92-104, 2009 | 57 | 2009 |
Tumor targeting by a multivalent single-chain Fv (scFv) anti-Lewis Y antibody construct MP Kelly, FT Lee, K Tahtis, BE Power, FE Smyth, MW Brechbiel, ... Cancer biotherapy & radiopharmaceuticals 23 (4), 411-424, 2008 | 56 | 2008 |
Analgesic efficacy and safety of the novel p38 MAP kinase inhibitor, losmapimod, in patients with neuropathic pain following peripheral nerve injury: a double‐blind, placebo … T Ostenfeld, A Krishen, RY Lai, J Bullman, AJ Baines, J Green, P Anand, ... European Journal of Pain 17 (6), 844-857, 2013 | 54 | 2013 |
Enhanced efficacy of 90Y-radiolabeled anti-Lewis Y humanized monoclonal antibody hu3S193 and paclitaxel combined-modality radioimmunotherapy in a breast cancer model MP Kelly, FT Lee, FE Smyth, MW Brechbiel, AM Scott Journal of Nuclear Medicine 47 (4), 716-725, 2006 | 54 | 2006 |
Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning L Haber, K Olson, MP Kelly, A Crawford, DJ DiLillo, R Tavaré, E Ullman, ... Scientific Reports 11 (1), 14397, 2021 | 47 | 2021 |
Radioimmunotherapy with α-Particle–Emitting 213Bi-C-Functionalized trans-Cyclohexyl-Diethylenetriaminepentaacetic Acid-Humanized 3S193 Is Enhanced by Combination with … MP Kelly, FT Lee, K Tahtis, FE Smyth, MW Brechbiel, AM Scott Clinical cancer research 13 (18), 5604s-5612s, 2007 | 41 | 2007 |
Recently recognised microbial enteropathies and HIV infection MJG Farthing, MP Kelly, AM Veitch Journal of Antimicrobial Chemotherapy 37 (suppl_B), 61-70, 1996 | 39 | 1996 |
Differential regulation of ventricular adrenomedullin and atrial natriuretic peptide gene expression in pressure and volume overload in the rat M Kaiser, O Kahr, Y Shimada, P Smith, M Kelly, H Mahadeva, M Adams, ... Clinical Science 94 (4), 359-365, 1998 | 36 | 1998 |
Bispecific antigen-binding molecules that bind MUC16 and CD3, and compositions thereof L Haber, E Smith, M Kelly, JR Kirshner, S Coetzee, A Crawford, T Nittoli, ... US Patent 10,738,130, 2020 | 34 | 2020 |
Conceptualising chronic illness M Kelly, D Field Sociological perspectives on health, illness and health care. Oxford …, 1998 | 34 | 1998 |
Excavations at a Neolithic Cursus, Springfield, Essex, 1979–85 DG Buckley, JD Hedges, N Brown, E Healey, L Hurcombe, M Kelly, ... Proceedings of the Prehistoric Society 67, 101-162, 2001 | 29 | 2001 |
Antibody drug conjugates of cleavable amino-alkyl and aryl maytansinoids T Nittoli, MP Kelly, F Delfino, J Rudge, A Kunz, T Markotan, J Spink, ... Bioorganic & Medicinal Chemistry 26 (9), 2271-2279, 2018 | 27 | 2018 |
A biparatopic antibody–drug conjugate to treat MET-expressing cancers, including those that are unresponsive to MET pathway blockade JO DaSilva, K Yang, O Surriga, T Nittoli, A Kunz, MC Franklin, FJ Delfino, ... Molecular Cancer Therapeutics 20 (10), 1966-1976, 2021 | 26 | 2021 |
Preclinical activity of the novel anti-prolactin receptor (prlr) antibody–drug conjugate regn2878-dm1 in prlr-positive breast cancers MP Kelly, C Hickey, S Makonnen, S Coetzee, S Jalal, Y Wang, F Delfino, ... Molecular Cancer Therapeutics 16 (7), 1299-1311, 2017 | 25 | 2017 |