Flagellar motility is required for the viability of the bloodstream trypanosome R Broadhead, HR Dawe, H Farr, S Griffiths, SR Hart, N Portman, ... Nature 440 (7081), 224-227, 2006 | 559 | 2006 |
Targeting CDK2 in cancer: challenges and opportunities for therapy S Tadesse, AT Anshabo, N Portman, E Lim, W Tilley, CE Caldon, S Wang Drug discovery today 25 (2), 406-413, 2020 | 175 | 2020 |
Swimming with protists: perception, motility and flagellum assembly ML Ginger, N Portman, PG McKean Nature Reviews Microbiology 6 (11), 838-850, 2008 | 166 | 2008 |
The paraflagellar rod of kinetoplastid parasites: from structure to components and function N Portman, K Gull International journal for parasitology 40 (2), 135-148, 2010 | 163 | 2010 |
Overcoming CDK4/6 inhibitor resistance in ER-positive breast cancer N Portman, S Alexandrou, E Carson, S Wang, E Lim, CE Caldon Endocrine-related cancer 26 (1), R15-R30, 2019 | 132 | 2019 |
The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis HR Dawe, H Farr, N Portman, MK Shaw, K Gull Journal of cell science 118 (23), 5421-5430, 2005 | 99 | 2005 |
Combining RNA interference mutants and comparative proteomics to identify protein components and dependences in a eukaryotic flagellum N Portman, S Lacomble, B Thomas, PG McKean, K Gull Journal of Biological Chemistry 284 (9), 5610-5619, 2009 | 84 | 2009 |
Blocking Variant Surface Glycoprotein Synthesis in Trypanosoma brucei Triggers a General Arrest in Translation Initiation TK Smith, N Vasileva, E Gluenz, S Terry, N Portman, S Kramer, ... PloS one 4 (10), e7532, 2009 | 65 | 2009 |
RNA interference mutant induction in vivo demonstrates the essential nature of trypanosome flagellar function during mammalian infection S Griffiths, N Portman, PR Taylor, S Gordon, ML Ginger, K Gull Eukaryotic cell 6 (7), 1248-1250, 2007 | 52 | 2007 |
Pushing estrogen receptor around in breast cancer E Lim, G Tarulli, N Portman, TE Hickey, WD Tilley, C Palmieri Endocrine-related cancer 23 (12), T227-T241, 2016 | 51 | 2016 |
Co-targeting CDK4/6 and AKT with endocrine therapy prevents progression in CDK4/6 inhibitor and endocrine therapy-resistant breast cancer CL Alves, S Ehmsen, MG Terp, N Portman, M Tuttolomondo, ... Nature Communications 12 (1), 5112, 2021 | 47 | 2021 |
Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer SP Kennedy, JZR Han, N Portman, M Nobis, JF Hastings, KJ Murphy, ... Breast Cancer Research 21, 1-17, 2019 | 43 | 2019 |
Protein diversity in discrete structures at the distal tip of the trypanosome flagellum V Varga, F Moreira-Leite, N Portman, K Gull Proceedings of the National Academy of Sciences 114 (32), E6546-E6555, 2017 | 43 | 2017 |
MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer N Portman, HH Milioli, S Alexandrou, R Coulson, A Yong, KJ Fernandez, ... Breast Cancer Research 22, 1-17, 2020 | 42 | 2020 |
Serum response factor cleavage by caspases 3 and 7 linked to apoptosis in human BJAB cells V Drewett, A Devitt, J Saxton, N Portman, P Greaney, NE Cheong, ... Journal of Biological Chemistry 276 (36), 33444-33451, 2001 | 42 | 2001 |
DNA methylation is required to maintain both DNA replication timing precision and 3D genome organization integrity Q Du, GC Smith, PL Luu, JM Ferguson, NJ Armstrong, CE Caldon, ... Cell Reports 36 (12), 2021 | 41 | 2021 |
Evidence of intraflagellar transport and apical complex formation in a free-living relative of the apicomplexa N Portman, C Foster, G Walker, J Šlapeta Eukaryotic cell 13 (1), 10-20, 2014 | 41 | 2014 |
Analysis of the trypanosome flagellar proteome using a combined electron transfer/collisionally activated dissociation strategy SR Hart, KW Lau, Z Hao, R Broadhead, N Portman, A Hühmer, K Gull, ... Journal of the American Society for Mass Spectrometry 20, 167-175, 2009 | 41 | 2009 |
The flagellar contribution to the apical complex: a new tool for the eukaryotic Swiss Army knife? N Portman, J Šlapeta Trends in parasitology 30 (2), 58-64, 2014 | 39 | 2014 |
A protein-protein interaction map of the Trypanosoma brucei paraflagellar rod S Lacomble, N Portman, K Gull PLoS One 4 (11), e7685, 2009 | 34 | 2009 |