| Combination therapy targeting ribosome biogenesis and mRNA translation synergistically extends survival in MYC-driven lymphoma JR Devlin, KM Hannan, N Hein, C Cullinane, E Kusnadi, PY Ng, ... Cancer discovery 6 (1), 59-70, 2016 | 123 | 2016 |
| Regulation of rDNA transcription in response to growth factors, nutrients and energy EP Kusnadi, KM Hannan, RJ Hicks, RD Hannan, RB Pearson, J Kang Gene 556 (1), 27-34, 2015 | 106 | 2015 |
| The dual inhibition of RNA Pol I transcription and PIM kinase as a new therapeutic approach to treat advanced prostate cancer RJ Rebello, E Kusnadi, DP Cameron, HB Pearson, A Lesmana, JR Devlin, ... Clinical Cancer Research 22 (22), 5539-5552, 2016 | 80 | 2016 |
| Translational offsetting as a mode of estrogen receptor α‐dependent regulation of gene expression J Lorent, EP Kusnadi, V van Hoef, RJ Rebello, M Leibovitch, J Ristau, ... The EMBO journal 38 (23), e101323, 2019 | 34 | 2019 |
| Regulation of gene expression via translational buffering EP Kusnadi, C Timpone, I Topisirovic, O Larsson, L Furic Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1869 (1), 119140, 2022 | 25 | 2022 |
| A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction K Somers, VW Wen, SMC Middlemiss, B Osborne, H Forgham, MS Jung, ... Oncogene 38 (20), 3824-3842, 2019 | 22 | 2019 |
| Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis EP Kusnadi, AS Trigos, C Cullinane, DL Goode, O Larsson, JR Devlin, ... The EMBO journal 39 (21), e105111, 2020 | 18 | 2020 |
| Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC–Driven Cancer Progression J Gao, MS Jung, C Mayoh, P Venkat, KM Hannan, JI Fletcher, A Kamili, ... Cancer Research 80 (17), 3706-3718, 2020 | 15 | 2020 |
| Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death A Domostegui, S Peddigari, CA Mercer, F Iannizzotto, ML Rodriguez, ... Blood, The Journal of the American Society of Hematology 137 (24), 3351-3364, 2021 | 13 | 2021 |
| Arginine-rich C9ORF72 ALS proteins stall ribosomes in a manner distinct from a canonical ribosome-associated quality control substrate V Kriachkov, AR Ormsby, EP Kusnadi, HEG McWilliam, JD Mintern, ... Journal of Biological Chemistry 299 (1), 2023 | 12 | 2023 |
| Regulation of mRNA Translation by Hormone Receptors in Breast and Prostate Cancer J Xie, EP Kusnadi, L Furic, LA Selth Cancers 13 (13), 3254, 2021 | 11 | 2021 |
| Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription J Kang, EP Kusnadi, AJ Ogden, RJ Hicks, L Bammert, U Kutay, S Hung, ... Oncotarget 7 (31), 48887, 2016 | 11 | 2016 |
| Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAFV600 melanoma LK Smith, T Parmenter, M Kleinschmidt, EP Kusnadi, J Kang, CA Martin, ... Nature Communications 13 (1), 1100, 2022 | 7 | 2022 |
| PMR-116, a second generation RNA Polymerase I inhibitor L Furic, N Hein, R Ferreira, K Panov, A Huglo, R Rebello, E Kusnadi, ... Cancer Research 84 (6_Supplement), 3326-3326, 2024 | | 2024 |
| Multi-omics approach reveals a SMAD4-deficiency signature, translational reprogramming and synthetic lethality in esophageal adenocarcinom JV Milne, K Fujihara, E Kusnadi, M Pechlivanis, N Thio, C Cabalag, ... Cancer Research 84 (6_Supplement), 5578-5578, 2024 | | 2024 |
| Abstract A176: Loss of SMAD4 unleashes mTOR and increases dependency on cap-dependent translation in esophageal tumorigenesis JV Milne, E Mustafa, K Fujihara, E Kusnadi, N Thio, M Pechlivanis, ... Molecular Cancer Therapeutics 22 (12_Supplement), A176-A176, 2023 | | 2023 |
| Adaptive post-transcriptional reprogramming of metabolism limits response to targeted therapy in BRAFV600 melanoma LK Smith, T Parmenter, M Kleinschmidt, EP Kusnadi, J Kang, CA Martin, ... | | 2019 |
| Dual inhibition of RNA Pol I transcription and PIM kinase as a new therapy to treat advanced prostate cancer R Rebello, E Kusnadi, D Cameron, H Pearson, A Lesmana, J Devlin, ... CLINICAL ENDOCRINOLOGY 86, 1-1, 2017 | | 2017 |
Rick PearsonGroup Leader, Peter MacCallum Cancer CentreVerified email at petermac.org
