| ELISA in the multiplex era: potentials and pitfalls PJ Tighe, RR Ryder, I Todd, LC Fairclough PROTEOMICS–Clinical Applications 9 (3-4), 406-422, 2015 | 436 | 2015 |
| The cysteine protease activity of the major dust mite allergen Der p 1 selectively enhances the immunoglobulin E antibody response L Gough, O Schulz, HF Sewell, F Shakib The Journal of experimental medicine 190 (12), 1897-1902, 1999 | 261 | 1999 |
| The proteolytic activity of the major dust mite allergen Der p 1 conditions dendritic cells to produce less interleukin‐12: allergen‐induced Th2 bias determined at the … AM Ghaemmaghami, L Gough, HF Sewell, F Shakib Clinical & Experimental Allergy 32 (10), 1468-1475, 2002 | 200 | 2002 |
| Activity profile of dust mite allergen extract using substrate libraries and functional proteomic microarrays J Harris, DE Mason, J Li, KW Burdick, BJ Backes, T Chen, A Shipway, ... Chemistry & biology 11 (10), 1361-1372, 2004 | 130 | 2004 |
| Human T cell subset commitment determined by the intrinsic property of antigen: the proteolytic activity of the major mite allergen Der p 1 conditions T cells to produce more … AM Ghaemmaghami, A Robins, L Gough, HF Sewell, F Shakib European Journal of Immunology 31 (4), 1211-1216, 2001 | 127 | 2001 |
| Regulation in chronic obstructive pulmonary disease: the role of regulatory T-cells and Th17 cells N Lane, RA Robins, J Corne, L Fairclough Clinical science 119 (2), 75-86, 2010 | 117 | 2010 |
| The proteolytic activity of the major dust mite allergen Der p 1 enhances the IgE antibody response to a bystander antigen L Gough, HF Sewell, F Shakib Clinical & Experimental Allergy 31 (10), 1594-1598, 2001 | 117 | 2001 |
| Quantitative validation and comparison of multiplex cytokine kits JL Richens, RA Urbanowicz, R Metcalf, J Corne, P O’Shea, L Fairclough Journal of biomolecular screening 15 (5), 562-568, 2010 | 114 | 2010 |
| Enhanced effector function of cytotoxic cells in the induced sputum of COPD patients RA Urbanowicz, JR Lamb, I Todd, JM Corne, LC Fairclough Respiratory research 11, 1-9, 2010 | 103 | 2010 |
| Utility, reliability and reproducibility of immunoassay multiplex kits P Tighe, O Negm, I Todd, L Fairclough Methods 61 (1), 23-29, 2013 | 97 | 2013 |
| Proteolytic activity of the house dust mite allergen Der p 1 enhances allergenicity in a mouse inhalation model L Gough, E Campbell, D Bayley, G Van Heeke, F Shakib Clinical & Experimental Allergy 33 (8), 1159-1163, 2003 | 96 | 2003 |
| Altered effector function of peripheral cytotoxic cells in COPD RA Urbanowicz, JR Lamb, I Todd, JM Corne, LC Fairclough Respiratory research 10, 1-13, 2009 | 80 | 2009 |
| Killer cells in chronic obstructive pulmonary disease L Fairclough, RA Urbanowicz, J Corne, JR Lamb Clinical science 114 (8), 533-541, 2008 | 78 | 2008 |
| Differential activation of killer cells in the circulation and the lung: a study of current smoking status and chronic obstructive pulmonary disease (COPD) J Wang, RA Urbanowicz, PJ Tighe, I Todd, JM Corne, LC Fairclough PLoS One 8 (3), e58556, 2013 | 66 | 2013 |
| Prophylactic antibiotic use in COPD and the potential anti-inflammatory activities of antibiotics AW Huckle, LC Fairclough, I Todd Respiratory care 63 (5), 609-619, 2018 | 59 | 2018 |
| Highly sensitive label-free antibody detection using a long period fibre grating sensor LL Liu, L Marques, R Correia, SP Morgan, SW Lee, P Tighe, L Fairclough, ... Sensors and Actuators B: Chemical 271, 24-32, 2018 | 53 | 2018 |
| IgE autoantibodies and their association with the disease activity and phenotype in bullous pemphigoid: a systematic review AH Saniklidou, PJ Tighe, LC Fairclough, I Todd Archives of dermatological research 310, 11-28, 2018 | 52 | 2018 |
| Cigarette smoking differentially affects immunoglobulin class levels in serum and saliva: An investigation and review N Tarbiah, I Todd, PJ Tighe, LC Fairclough Basic & Clinical Pharmacology & Toxicology 125 (5), 474-483, 2019 | 50 | 2019 |
| The detection of ADAM8 protein on cells of the human immune system and the demonstration of its expression on peripheral blood B cells, dendritic cells and monocyte subsets J Richens, L Fairclough, AM Ghaemmaghami, J Mahdavi, F Shakib, ... Immunobiology 212 (1), 29-38, 2007 | 50 | 2007 |
| Multiple circulating cytokines are coelevated in chronic obstructive pulmonary disease S Selvarajah, I Todd, PJ Tighe, M John, CE Bolton, T Harrison, ... Mediators of Inflammation 2016, 2016 | 49 | 2016 |
