| Design, synthesis, and study of a mycobactin− artemisinin conjugate that has selective and potent activity against tuberculosis and malaria MJ Miller, AJ Walz, H Zhu, C Wu, G Moraski, U Möllmann, EM Tristani, ... Journal of the American chemical society 133 (7), 2076-2079, 2011 | 174 | 2011 |
| EzrA prevents aberrant cell division by modulating assembly of the cytoskeletal protein FtsZ DP Haeusser, RL Schwartz, AM Smith, ME Oates, PA Levin Molecular microbiology 52 (3), 801-814, 2004 | 146 | 2004 |
| SpoT governs Legionella pneumophila differentiation in host macrophages ZD Dalebroux, RL Edwards, MS Swanson Molecular microbiology 71 (3), 640-658, 2009 | 132 | 2009 |
| Control of bone anabolism in response to mechanical loading and PTH by distinct mechanisms downstream of the PTH receptor J Delgado‐Calle, X Tu, R Pacheco‐Costa, K McAndrews, R Edwards, ... Journal of Bone and Mineral Research 32 (3), 522-535, 2017 | 101 | 2017 |
| A sugar phosphatase regulates the methylerythritol phosphate (MEP) pathway in malaria parasites AM Guggisberg, J Park, RL Edwards, ML Kelly, DM Hodge, NH Tolia, ... Nature communications 5 (1), 4467, 2014 | 85 | 2014 |
| Legionella pneumophila couples fatty acid flux to microbial differentiation and virulence RL Edwards, ZD Dalebroux, MS Swanson Molecular microbiology 71 (5), 1190-1204, 2009 | 75 | 2009 |
| Polymer stability plays an important role in the positional regulation of FtsZ PA Levin, RL Schwartz, AD Grossman Journal of bacteriology 183 (18), 5449-5452, 2001 | 70 | 2001 |
| Plasmodium IspD (2-C-Methyl-d-erythritol 4-Phosphate Cytidyltransferase), an Essential and Druggable Antimalarial Target LS Imlay, CM Armstrong, MC Masters, T Li, KE Price, RL Edwards, ... ACS Infectious Diseases 1 (4), 157-167, 2015 | 66 | 2015 |
| Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13 NF Gnädig, BH Stokes, RL Edwards, GF Kalantarov, KC Heimsch, ... PLoS pathogens 16 (4), e1008482, 2020 | 65 | 2020 |
| Effect of decreasing column inner diameter and use of off-line two-dimensional chromatography on metabolite detection in complex mixtures JL Edwards, RL Edwards, KR Reid, RT Kennedy Journal of chromatography A 1172 (2), 127-134, 2007 | 57 | 2007 |
| Double-blind trial of vitamin C in elderly hypertensives. LB Lovat, Y Lu, AJ Palmer, R Edwards, AE Fletcher, CJ Bulpitt Journal of human hypertension 7 (4), 403-405, 1993 | 46 | 1993 |
| The Legionella pneumophila LetA/LetS Two-Component System Exhibits Rheostat-Like Behavior RL Edwards, M Jules, T Sahr, C Buchrieser, MS Swanson Infection and immunity 78 (6), 2571-2583, 2010 | 43 | 2010 |
| Surveillance of patients post-endovascular abdominal aortic aneurysm repair (EVAR). A web-based survey of practice in the UK A Patel, R Edwards, S Chandramohan Clinical radiology 68 (6), 580-587, 2013 | 41 | 2013 |
| The medicinal chemistry of tuberculosis chemotherapy GA Marriner, A Nayyar, E Uh, SY Wong, T Mukherjee, LE Via, M Carroll, ... Third World Diseases, 47-124, 2011 | 34 | 2011 |
| MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis RL Edwards, RC Brothers, X Wang, MI Maron, PD Ziniel, PS Tsang, ... Scientific reports 7 (1), 8400, 2017 | 33 | 2017 |
| Structure–activity relationships of the MEPicides: N-acyl and O-linked analogs of FR900098 as inhibitors of Dxr from Mycobacterium tuberculosis and Yersinia pestis G San Jose, ER Jackson, A Haymond, C Johny, RL Edwards, X Wang, ... ACS infectious diseases 2 (12), 923-935, 2016 | 31 | 2016 |
| The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation RC Henrici, RL Edwards, M Zoltner, DA van Schalkwyk, MN Hart, ... MBio 11 (1), 10.1128/mbio. 02918-19, 2020 | 28* | 2020 |
| MEPicides: α, β-unsaturated fosmidomycin analogues as DXR inhibitors against malaria X Wang, RL Edwards, H Ball, C Johnson, A Haymond, M Girma, ... Journal of medicinal chemistry 61 (19), 8847-8858, 2018 | 28 | 2018 |
| Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose … MR Heitmeier, RC Hresko, RL Edwards, MJ Prinsen, MXG Ilagan, ... PloS one 14 (5), e0216457, 2019 | 26 | 2019 |
| A novel fluorescence resonance energy transfer-based screen in high-throughput format to identify inhibitors of malarial and human glucose transporters TE Kraft, MR Heitmeier, M Putanko, RL Edwards, MXG Ilagan, MA Payne, ... Antimicrobial agents and chemotherapy 60 (12), 7407-7414, 2016 | 26 | 2016 |
