Golden Gate Assembly of CRISPR gRNA expression array for simultaneously targeting multiple genes J Vad-Nielsen, L Lin, L Bolund, AL Nielsen, Y Luo Cellular and molecular life sciences 73, 4315-4325, 2016 | 60 | 2016 |
MET amplification and epithelial-to-mesenchymal transition exist as parallel resistance mechanisms in erlotinib-resistant, EGFR-mutated, NSCLC HCC827 cells KR Jakobsen, C Demuth, AT Madsen, D Hussmann, J Vad-Nielsen, ... Oncogenesis 6 (4), e307-e307, 2017 | 54 | 2017 |
Beyond the histone tale: HP1α deregulation in breast cancer epigenetics J Vad-Nielsen, AL Nielsen Cancer Biology & Therapy 16 (2), 189-200, 2015 | 39 | 2015 |
Histone Deacetylase Inhibitor Romidepsin Inhibits De Novo HIV-1 Infections KL Jønsson, M Tolstrup, J Vad-Nielsen, K Kjær, A Laustsen, ... Antimicrobial Agents and Chemotherapy 59 (7), 3984-3994, 2015 | 29 | 2015 |
Up-regulated FGFR1 expression as a mediator of intrinsic TKI resistance in EGFR-mutated NSCLC KR Gammelgaard, J Vad-Nielsen, MS Clement, S Weiss, TF Daugaard, ... Translational Oncology 12 (3), 432-440, 2019 | 24 | 2019 |
Cause-and-Effect relationship between FGFR1 expression and epithelial-mesenchymal transition in EGFR-mutated non-small cell lung cancer cells J Vad-Nielsen, KR Gammelgaard, TF Daugaard, AL Nielsen Lung Cancer 132, 132-140, 2019 | 20 | 2019 |
Regulatory dissection of the CBX5 and hnRNPA1 bi-directional promoter in human breast cancer cells reveals novel transcript variants differentially associated … J Vad-Nielsen, KR Jakobsen, TF Daugaard, R Thomsen, A Brügmann, ... BMC cancer 16, 1-21, 2016 | 20 | 2016 |
The IFNL4 Gene Is a Noncanonical Interferon Gene with a Unique but Evolutionarily Conserved Regulation H Zhou, M Møhlenberg, E Terczyńska-Dyla, KG Winther, NH Hansen, ... Journal of virology 94 (5), 10.1128/jvi. 01535-19, 2020 | 17 | 2020 |
Administration of panobinostat is associated with increased IL-17A mRNA in the intestinal epithelium of HIV-1 patients A Bjerg Christensen, A Dige, J Vad-Nielsen, CR Brinkmann, M Bendix, ... Mediators of inflammation 2015, 2015 | 13 | 2015 |
Cell-free Chromatin Immunoprecipitation (cfChIP) from blood plasma can determine gene-expression in tumors from non-small-cell lung cancer patients J Vad-Nielsen, P Meldgaard, BS Sorensen, AL Nielsen Lung Cancer 147, 244-251, 2020 | 12 | 2020 |
EGFR transcription in non‐small‐cell lung cancer tumours can be revealed in ctDNA by cell‐free chromatin immunoprecipitation (cfChIP) CT Månsson, J Vad‐Nielsen, P Meldgaard, AL Nielsen, BS Sorensen Molecular Oncology 15 (11), 2868-2876, 2021 | 8 | 2021 |
A golden gate-based protocol for assembly of multiplexed gRNA expression arrays for CRISPR/Cas9 J Vad-Nielsen, L Lin, KT Jensen, AL Nielsen, Y Luo Bio-protocol 6 (23), e2059-e2059, 2016 | 5 | 2016 |
Simple method for assembly of CRISPR synergistic activation mediator gRNA expression array J Vad-Nielsen, AL Nielsen, Y Luo Journal of biotechnology 274, 54-57, 2018 | 3 | 2018 |
Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT … J Vad-Nielsen, NH Staunstrup, ML Kjeldsen, N Dybdal, G Flandin, ... Translational Lung Cancer Research 12 (1), 42, 2023 | 2 | 2023 |
CRISPR-mediated multiplexed genetic manipulation L Lin, J Vad-Nielsen, Y Luo Oncotarget 7 (49), 80103, 2016 | 2 | 2016 |
CRISPR activation to characterize splice-altering variants in easily accessible cells T Terkelsen, NS Mikkelsen, EN Bak, J Vad-Nielsen, J Blechingberg, ... The American Journal of Human Genetics 111 (2), 309-322, 2024 | | 2024 |