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Lenka Munoz
Lenka Munoz
Verified email at sydney.edu.au
Title
Cited by
Cited by
Year
Targeting p38 MAPK pathway for the treatment of Alzheimer's disease
L Munoz, AJ Ammit
Neuropharmacology 58 (3), 561-568, 2010
4132010
Targeting cancer cell dormancy
A Recasens, L Munoz
Trends in pharmacological sciences 40 (2), 128-141, 2019
2632019
A novel p38α MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse …
L Munoz, HR Ranaivo, SM Roy, W Hu, JM Craft, LK McNamara, LW Chico, ...
Journal of neuroinflammation 4, 1-14, 2007
2592007
Interleukins in glioblastoma pathophysiology: implications for therapy
YT Yeung, KL McDonald, T Grewal, L Munoz
British journal of pharmacology 168 (3), 591-606, 2013
2262013
DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications
R Abbassi, TG Johns, M Kassiou, L Munoz
Pharmacology & therapeutics 151, 87-98, 2015
1452015
Targeting p38 or MK2 enhances the anti-leukemic activity of Smac-mimetics
N Lalaoui, K Hänggi, G Brumatti, D Chau, NYN Nguyen, L Vasilikos, ...
Cancer cell 29 (2), 145-158, 2016
1212016
Non-kinase targets of protein kinase inhibitors
L Munoz
Nature Reviews Drug Discovery 16 (6), 424-440, 2017
1202017
Mitogen-activated protein kinase–activated protein kinase 2 in neuroinflammation, heat shock protein 27 phosphorylation, and cell cycle: role and targeting
FMS Gurgis, W Ziaziaris, L Munoz
Molecular pharmacology 85 (2), 345-356, 2014
1002014
Development of a novel therapeutic suppressor of brain proinflammatory cytokine up-regulation that attenuates synaptic dysfunction and behavioral deficits
W Hu, HR Ranaivo, SM Roy, HA Behanna, LK Wing, L Munoz, L Guo, ...
Bioorganic & medicinal chemistry letters 17 (2), 414-418, 2007
982007
p38 MAPK inhibitors attenuate pro-inflammatory cytokine production and the invasiveness of human U251 glioblastoma cells
YT Yeung, NS Bryce, S Adams, N Braidy, M Konayagi, KL McDonald, ...
Journal of neuro-oncology 109, 35-44, 2012
942012
The p38-MK2-HuR pathway potentiates EGFRvIII–IL-1β-driven IL-6 secretion in glioblastoma cells
FMS Gurgis, YT Yeung, MXM Tang, B Heng, M Buckland, AJ Ammit, ...
Oncogene 34 (22), 2934-2942, 2015
812015
Histone lysine demethylases and their functions in cancer
J Sterling, SV Menezes, RH Abbassi, L Munoz
International Journal of Cancer 148 (10), 2375-2388, 2021
642021
Structural optimization and pharmacological evaluation of inhibitors targeting dual-specificity tyrosine phosphorylation-regulated kinases (DYRK) and CDC-like kinases (CLK) in …
Q Zhou, AF Phoa, RH Abbassi, M Hoque, TA Reekie, JS Font, RM Ryan, ...
Journal of Medicinal Chemistry 60 (5), 2052-2070, 2017
472017
Novel p38 MAPK inhibitor ML3403 has potent anti-inflammatory activity in airway smooth muscle
L Munoz, EE Ramsay, M Manetsch, Q Ge, C Peifer, S Laufer, AJ Ammit
European journal of pharmacology 635 (1-3), 212-218, 2010
402010
Development and biological evaluation of a photoactivatable small molecule microtubule-targeting agent
A Döbber, AF Phoa, RH Abbassi, BW Stringer, BW Day, TG Johns, ...
ACS medicinal chemistry letters 8 (4), 395-400, 2017
372017
Optimisation of LRRK2 inhibitors and assessment of functional efficacy in cell-based models of neuroinflammation
L Munoz, ME Kavanagh, AF Phoa, B Heng, N Dzamko, EJ Chen, ...
European Journal of Medicinal Chemistry 95, 29-34, 2015
352015
Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells
A Recasens, SJ Humphrey, M Ellis, M Hoque, RH Abbassi, B Chen, ...
Cell death discovery 7 (1), 81, 2021
292021
Discovery and pharmacological evaluation of a novel series of adamantyl cyanoguanidines as P2X7 receptor antagonists
J O'Brien-Brown, A Jackson, TA Reekie, ML Barron, EL Werry, P Schiavini, ...
European Journal of Medicinal Chemistry 130, 433-439, 2017
292017
Kinase targets in CNS drug discovery
H Gunosewoyo, L Yu, L Munoz, M Kassiou
Future Medicinal Chemistry 9 (3), 303-314, 2017
292017
Fluorescence polarization binding assay to develop inhibitors of inactive p38α mitogen-activated protein kinase
L Munoz, R Selig, YT Yeung, C Peifer, D Hauser, S Laufer
Analytical biochemistry 401 (1), 125-133, 2010
252010
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