Immune self-reactivity triggered by drug-modified HLA-peptide repertoire PT Illing, JP Vivian, NL Dudek, L Kostenko, Z Chen, M Bharadwaj, ... Nature 486 (7404), 554-558, 2012 | 754 | 2012 |
Human CD8+ T cell cross-reactivity across influenza A, B and C viruses M Koutsakos, PT Illing, THO Nguyen, NA Mifsud, JC Crawford, S Rizzetto, ... Nature immunology 20 (5), 613-625, 2019 | 201 | 2019 |
Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor R Reantragoon, L Kjer-Nielsen, O Patel, Z Chen, PT Illing, M Bhati, ... Journal of Experimental Medicine 209 (4), 761-774, 2012 | 199 | 2012 |
Drug hypersensitivity and human leukocyte antigens of the major histocompatibility complex M Bharadwaj, P Illing, A Theodossis, AW Purcell, J Rossjohn, ... Annual review of pharmacology and toxicology 52, 401-431, 2012 | 190 | 2012 |
A subset of HLA-I peptides are not genomically templated: Evidence for cis-and trans-spliced peptide ligands P Faridi, C Li, SH Ramarathinam, JP Vivian, PT Illing, NA Mifsud, R Ayala, ... Science immunology 3 (28), eaar3947, 2018 | 154 | 2018 |
MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape P Pymm, PT Illing, SH Ramarathinam, GM O'Connor, VA Hughes, ... Nature structural & molecular biology 24 (4), 387-394, 2017 | 97 | 2017 |
Human leukocyte antigen-associated drug hypersensitivity PT Illing, JP Vivian, AW Purcell, J Rossjohn, J McCluskey Current opinion in immunology 25 (1), 81-89, 2013 | 96 | 2013 |
Downregulation of MHC class I expression by influenza A and B viruses M Koutsakos, HEG McWilliam, TE Aktepe, S Fritzlar, PT Illing, NA Mifsud, ... Frontiers in immunology 10, 1158, 2019 | 88 | 2019 |
The role of HLA genes in pharmacogenomics: unravelling HLA associated adverse drug reactions PT Illing, AW Purcell, J McCluskey Immunogenetics 69, 617-630, 2017 | 78 | 2017 |
HLA‐associated antiepileptic drug‐induced cutaneous adverse reactions KA Mullan, A Anderson, PT Illing, P Kwan, AW Purcell, NA Mifsud Hla 93 (6), 417-435, 2019 | 68 | 2019 |
The cellular redox environment alters antigen presentation JA Trujillo, NP Croft, NL Dudek, R Channappanavar, A Theodossis, ... Journal of Biological Chemistry 289 (40), 27979-27991, 2014 | 66 | 2014 |
Constitutive and inflammatory immunopeptidome of pancreatic β-cells NL Dudek, CT Tan, DG Gorasia, NP Croft, PT Illing, AW Purcell Diabetes 61 (11), 3018-3025, 2012 | 63 | 2012 |
Allotype specific interactions of drugs and HLA molecules in hypersensitivity reactions PT Illing, NA Mifsud, AW Purcell Current Opinion in Immunology 42, 31-40, 2016 | 61 | 2016 |
The molecular basis for peptide repertoire selection in the human leukocyte antigen (HLA) C* 06: 02 molecule JI Mobbs, PT Illing, NL Dudek, AG Brooks, DG Baker, AW Purcell, ... Journal of Biological Chemistry 292 (42), 17203-17215, 2017 | 42 | 2017 |
Anthem: a user customised tool for fast and accurate prediction of binding between peptides and HLA class I molecules S Mei, F Li, D Xiang, R Ayala, P Faridi, GI Webb, PT Illing, J Rossjohn, ... Briefings in Bioinformatics 22 (5), bbaa415, 2021 | 40 | 2021 |
HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome PT Illing, P Pymm, NP Croft, HG Hilton, V Jojic, AS Han, JL Mendoza, ... Nature communications 9 (1), 4693, 2018 | 38 | 2018 |
A natural product compound inhibits coronaviral replication in vitro by binding to the conserved Nsp9 SARS-CoV-2 protein DR Littler, M Liu, JL McAuley, SA Lowery, PT Illing, BS Gully, AW Purcell, ... Journal of Biological Chemistry 297 (6), 2021 | 37 | 2021 |
Identification of flucloxacillin-haptenated HLA-B* 57: 01 ligands: evidence of antigen processing and presentation JC Waddington, X Meng, PT Illing, A Tailor, K Adair, P Whitaker, J Hamlett, ... Toxicological Sciences 177 (2), 454-465, 2020 | 29 | 2020 |
Immunopeptidomic analysis reveals that deamidated HLA-bound peptides arise predominantly from deglycosylated precursors S Mei, R Ayala, SH Ramarathinam, PT Illing, P Faridi, J Song, AW Purcell, ... Molecular & Cellular Proteomics 19 (7), 1236-1247, 2020 | 29 | 2020 |
A comprehensive analysis of peptides presented by HLA‐A1 K Giam, R Ayala‐Perez, PT Illing, RB Schittenhelm, NP Croft, AW Purcell, ... Tissue Antigens 85 (6), 492-496, 2015 | 27 | 2015 |