| LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network Z Liu, N Bryant, R Kumaran, A Beilina, A Abeliovich, MR Cookson, ... Human molecular genetics 27 (2), 385-395, 2018 | 240 | 2018 |
| G2019S-LRRK2 expression augments α-synuclein sequestration into inclusions in neurons LA Volpicelli-Daley, H Abdelmotilib, Z Liu, L Stoyka, JPL Daher, ... Journal of Neuroscience 36 (28), 7415-7427, 2016 | 195 | 2016 |
| α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration AS Harms, V Delic, AD Thome, N Bryant, Z Liu, S Chandra, ... Acta neuropathologica communications 5, 1-16, 2017 | 175 | 2017 |
| α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration H Abdelmotilib, T Maltbie, V Delic, Z Liu, X Hu, KB Fraser, MS Moehle, ... Neurobiology of disease 105, 84-98, 2017 | 170 | 2017 |
| Screening of fungi for potential application of self-healing concrete RR Menon, J Luo, X Chen, H Zhou, Z Liu, G Zhou, N Zhang, C Jin Scientific reports 9 (1), 2075, 2019 | 103 | 2019 |
| Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers S Wang, Z Liu, T Ye, OS Mabrouk, T Maltbie, J Aasly, AB West Acta neuropathologica communications 5, 1-13, 2017 | 77 | 2017 |
| LRRK2 and Rab10 coordinate macropinocytosis to mediate immunological responses in phagocytes Z Liu, E Xu, HT Zhao, T Cole, AB West The EMBO Journal 39 (20), e104862, 2020 | 70 | 2020 |
| LRRK2 autophosphorylation enhances its GTPase activity Z Liu, JA Mobley, LJ DeLucas, RA Kahn, AB West The FASEB Journal 30 (1), 336, 2016 | 70 | 2016 |
| Sensitivity and specificity of Phospho‐Ser129 α‐synuclein monoclonal antibodies V Delic, S Chandra, H Abdelmotilib, T Maltbie, S Wang, D Kem, HJ Scott, ... Journal of Comparative Neurology 526 (12), 1978-1990, 2018 | 67 | 2018 |
| Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF) AA Ivanova, T Caspary, NT Seyfried, DM Duong, AB West, Z Liu, RA Kahn Journal of Biological Chemistry 292 (26), 11091-11108, 2017 | 53 | 2017 |
| Protective effects of xyloketal B against MPP+-induced neurotoxicity in Caenorhabditis elegans and PC12 cells X Lu, X Yao, Z Liu, H Zhang, W Li, Z Li, GL Wang, J Pang, Y Lin, Z Xu, ... Brain research 1332, 110-119, 2010 | 51 | 2010 |
| Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain E Xu, R Boddu, HA Abdelmotilib, A Sokratian, K Kelly, Z Liu, N Bryant, ... Molecular Neurodegeneration 17, 1-19, 2022 | 48 | 2022 |
| The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition K Kelly, S Wang, R Boddu, Z Liu, O Moukha-Chafiq, C Augelli-Szafran, ... Experimental neurology 309, 1-13, 2018 | 46 | 2018 |
| dl-3n-Butylphthalide promotes angiogenesis via the extracellular signal-regulated kinase 1/2 and phosphatidylinositol 3-kinase/Akt-endothelial nitric oxide synthase signaling … X Lu, D Luo, X Yao, G Wang, Z Liu, Z Li, W Li, F Chang, L Wen, SM Lee, ... Journal of Cardiovascular Pharmacology 59 (4), 352-362, 2012 | 45 | 2012 |
| Unique functional and structural properties of the LRRK2 protein ATP-binding pocket Z Liu, RA Galemmo, KB Fraser, MS Moehle, S Sen, LA Volpicelli-Daley, ... Journal of Biological Chemistry 289 (47), 32937-32951, 2014 | 41 | 2014 |
| Identification of LRRK2 missense variants in the accelerating medicines partnership Parkinson’s disease cohort N Bryant, N Malpeli, J Ziaee, C Blauwendraat, Z Liu, AMP PD Consortium, ... Human molecular genetics 30 (6), 454-466, 2021 | 26 | 2021 |
| Absence of mutations in exon 6 of the TARDBP gene in 207 Chinese patients with sporadic amyotrohic lateral sclerosis C Ye, X Lu, M Zheng, J Zhen, ZP Li, L Shi, Z Liu, L Feng, Z Pei, X Yao PLoS One 8 (7), e68106, 2013 | 10 | 2013 |
| Anionic nanoplastic contaminants promote Parkinson’s disease–associated α-synuclein aggregation Z Liu, A Sokratian, AM Duda, E Xu, C Stanhope, A Fu, S Strader, H Li, ... Science Advances 9 (46), eadi8716, 2023 | 9 | 2023 |
| The dual enzyme LRRK2 hydrolyzes GTP in both its GTPase and kinase domains in vitro Z Liu, AB West Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1865 (3), 274-280, 2017 | 3 | 2017 |
| RAB32 Ser71Arg in autosomal dominant Parkinson's disease: linkage, association, and functional analyses EK Gustavsson, J Follett, J Trinh, SK Barodia, R Real, Z Liu, ... The Lancet Neurology, 2024 | 1 | 2024 |
