| Structure− activity relationships for substituted bis (acridine-4-carboxamides): a new class of anticancer agents SA Gamage, JA Spicer, GJ Atwell, GJ Finlay, BC Baguley, WA Denny Journal of Medicinal Chemistry 42 (13), 2383-2393, 1999 | 197 | 1999 |
| Structure− activity relationships for pyrido-, imidazo-, pyrazolo-, pyrazino-, and pyrrolophenazinecarboxamides as topoisomerase-targeted anticancer agents SA Gamage, JA Spicer, GW Rewcastle, J Milton, S Sohal, W Dangerfield, ... Journal of medicinal chemistry 45 (3), 740-743, 2002 | 179 | 2002 |
| Bis (phenazine-1-carboxamides): Structure− activity relationships for a new class of dual topoisomerase I/II-directed anticancer drugs JA Spicer, SA Gamage, GW Rewcastle, GJ Finlay, DJA Bridewell, ... Journal of Medicinal Chemistry 43 (7), 1350-1358, 2000 | 112 | 2000 |
| Structure−Activity Relationships for Acridine-Substituted Analogues of the Mixed Topoisomerase I/II Inhibitor N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide JA Spicer, SA Gamage, GJ Atwell, GJ Finlay, BC Baguley, WA Denny Journal of medicinal chemistry 40 (12), 1919-1929, 1997 | 108 | 1997 |
| Identification of conjugated triene oxidation products of. alpha.-farnesene in apple skin DD Rowan, JM Allen, S Fielder, JA Spicer, MA Brimble Journal of Agricultural and Food Chemistry 43 (8), 2040-2045, 1995 | 99 | 1995 |
| Dicationic bis (9-methylphenazine-1-carboxamides): relationships between biological activity and linker chain structure for a series of potent topoisomerase targeted anticancer … SA Gamage, JA Spicer, GJ Finlay, AJ Stewart, P Charlton, BC Baguley, ... Journal of medicinal chemistry 44 (9), 1407-1415, 2001 | 89 | 2001 |
| Activation of a PAK‐MEK signalling pathway in malaria parasite‐infected erythrocytes A Sicard, JP Semblat, C Doerig, R Hamelin, M Moniatte, D Dorin‐Semblat, ... Cellular microbiology 13 (6), 836-845, 2011 | 80 | 2011 |
| A Selective and Slowly Reversible Inhibitor of l-Type Amino Acid Transporter 1 (LAT1) Potentiates Antiproliferative Drug Efficacy in Cancer Cells KM Huttunen, M Gynther, J Huttunen, E Puris, JA Spicer, WA Denny Journal of medicinal chemistry 59 (12), 5740-5751, 2016 | 66 | 2016 |
| Tyrosine Kinase Inhibitors. 20. Optimization of Substituted Quinazoline and Pyrido[3,4-d]pyrimidine Derivatives as Orally Active, Irreversible Inhibitors of the … JB Smaill, AJ Gonzales, JA Spicer, H Lee, JE Reed, K Sexton, IW Althaus, ... Journal of Medicinal Chemistry 59 (17), 8103-8124, 2016 | 59 | 2016 |
| 4-anilino-5-carboxamido-2-pyridone derivatives as noncompetitive inhibitors of mitogen-activated protein kinase kinase JA Spicer, GW Rewcastle, MD Kaufman, SL Black, MS Plummer, ... Journal of medicinal chemistry 50 (21), 5090-5102, 2007 | 56 | 2007 |
| Dihydrofuro[3,4-c]pyridinones as Inhibitors of the Cytolytic Effects of the Pore-Forming Glycoprotein Perforin G Lena, JA Trapani, VR Sutton, A Ciccone, KA Browne, MJ Smyth, ... Journal of medicinal chemistry 51 (23), 7614-7624, 2008 | 45 | 2008 |
| L-Type amino acid transporter 1 (lat1)-mediated targeted delivery of perforin inhibitors KM Huttunen, J Huttunen, I Aufderhaar, M Gynther, WA Denny, JA Spicer International journal of pharmaceutics 498 (1-2), 205-216, 2016 | 41 | 2016 |
| Exploration of a series of 5-arylidene-2-thioxoimidazolidin-4-ones as inhibitors of the cytolytic protein perforin JA Spicer, G Lena, DM Lyons, KM Huttunen, CK Miller, PD O’Connor, ... Journal of medicinal chemistry 56 (23), 9542-9555, 2013 | 37 | 2013 |
| Inhibition of the cellular function of perforin by 1-amino-2, 4-dicyanopyrido [1, 2-a] benzimidazoles DM Lyons, KM Huttunen, KA Browne, A Ciccone, JA Trapani, WA Denny, ... Bioorganic & medicinal chemistry 19 (13), 4091-4100, 2011 | 36 | 2011 |
| Systemic and brain pharmacokinetics of perforin inhibitor prodrugs M Gynther, DS Pickering, JA Spicer, WA Denny, KM Huttunen Molecular pharmaceutics 13 (7), 2484-2491, 2016 | 35 | 2016 |
| A new synthesis of substituted acridine-4-carboxylic acids and the anticancer drug N-[2-(dimethylamino) ethyl] acridine-4-carboxamide (DACA) SA Gamage, JA Spicer, GW Rewcastle, WA Denny Tetrahedron letters 38 (4), 699-702, 1997 | 31 | 1997 |
| Synthesis and evaluation of unsymmetrical bis (arylcarboxamides) designed as topoisomerase-targeted anticancer drugs JA Spicer, SA Gamage, GJ Finlay, WA Denny Bioorganic & medicinal chemistry 10 (1), 19-29, 2002 | 29 | 2002 |
| Dimeric analogues of non-cationic tricyclic aromatic carboxamides are a new class of cytotoxic agents JA Spicer, SA Gamage, GJ Atwell, GJ Finlay, BC Baguley, WA Denny Anti-cancer drug design 14 (3), 281-289, 1999 | 28 | 1999 |
| Inhibition of the pore-forming protein perforin by a series of aryl-substituted isobenzofuran-1 (3H)-ones JA Spicer, KM Huttunen, CK Miller, WA Denny, A Ciccone, KA Browne, ... Bioorganic & medicinal chemistry 20 (3), 1319-1336, 2012 | 25 | 2012 |
| Oxidation of α-farnesene JA Spicer, MA Brimble, DD Rowan Australian Journal of Chemistry 46 (12), 1929-1939, 1993 | 25 | 1993 |
