Albert J. R. Heck

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	All	Since 2016
Citations	54966	26183
h-index	116	76
i10-index	616	448

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Co-authors

Shabaz MohammedAssociate Professor of Proteomics, University of OxfordVerified email at bioch.ox.ac.uk
Maarten AltelaarProfessor, Universiteit UtrechtVerified email at uu.nl
Jeroen KrijgsveldGerman Cancer Research Center & Heidelberg UniversityVerified email at dkfz.de
Arjen ScholtenPrincipal Scientist Analytical Development; Janssen Vaccines & PreventionVerified email at its.jnj.com
Bas van BreukelenAssistant Professor, Biomolecular Mass Spectrometry and Proteomics Group, Utrecht UniversityVerified email at veluwestraat.nl
Teck Yew LowUKM Medical Molecular Biology InstituteVerified email at ppukm.ukm.edu.my
Reinout RaijmakersManaging Director, Bijvoet Center, Utrecht UniversityVerified email at uu.nl
Javier MuñozCNIO (Madrid, Spain)Verified email at cnio.es
Henk van den ToornBioinformatician at Biomolecular Mass Spectrometry and Proteomics Group, Utrecht UniversityVerified email at uu.nl
Joost SnijderUtrecht UniversityVerified email at uu.nl
Hans CleversHubrecht Institute - UtrechtVerified email at hubrecht.eu
C. MummeryLeiden University Medical Centre and University of TwenteVerified email at lumc.nl
Piero GiansantiChair of Proteomics and BioanalyticsVerified email at tum.de
Joost W. GouwScientist at Nutricia ResearchVerified email at interchange.ubc.ca
Alexander A. MakarovThermo Fisher ScientificVerified email at thermofisher.com
Fabio MarinoDipartimento di Scienze Chimiche, Farmaceutiche, Biologiche ed Ambientali. UNIME. CONISMA.Verified email at unime.it
Christian K. FreseMax Planck Unit for the Science of PathogensVerified email at mpusp.mpg.de
Fan LiuLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)Verified email at fmp-berlin.de
Daniele GuardavaccaroGroup leader, Hubrecht InstituteVerified email at hubrecht.eu
Richard ScheltemaUtrecht UniversityVerified email at uu.nl

Albert J. R. Heck

Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center and Utrecht University

Verified email at uu.nl - Homepage

Mass Spectrometry Proteomics Analytical Chemistry Stem Cells Pharmaceutical Sciences


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Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics PJ Boersema, R Raijmakers, S Lemeer, S Mohammed, AJR Heck Nature protocols 4 (4), 484-494, 2009	1250	2009
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling W De Lau, N Barker, TY Low, BK Koo, VSW Li, H Teunissen, P Kujala, ... Nature 476 (7360), 293-297, 2011	1051	2011
Selective isolation at the femtomole level of phosphopeptides from proteolytic digests using 2D-NanoLC-ESI-MS/MS and titanium oxide precolumns MWH Pinkse, PM Uitto, MJ Hilhorst, B Ooms, AJR Heck Analytical chemistry 76 (14), 3935-3943, 2004	1033	2004
The CRAPome: a contaminant repository for affinity purification–mass spectrometry data D Mellacheruvu, Z Wright, AL Couzens, JP Lambert, NA St-Denis, T Li, ... Nature methods 10 (8), 730-736, 2013	966	2013
Proteoform: a single term describing protein complexity LM Smith, NL Kelleher Nature methods 10 (3), 186-187, 2013	860	2013
Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex VSW Li, SS Ng, PJ Boersema, TY Low, WR Karthaus, JP Gerlach, ... Cell 149 (6), 1245-1256, 2012	737	2012
Native mass spectrometry: a bridge between interactomics and structural biology AJR Heck Nature methods 5 (11), 927-933, 2008	703	2008
The minimum information about a proteomics experiment (MIAPE) CF Taylor, NW Paton, KS Lilley, PA Binz, RK Julian, AR Jones, W Zhu, ... Nature biotechnology 25 (8), 887-893, 2007	703	2007
Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis JJ Benschop, S Mohammed, M O'Flaherty, AJR Heck, M Slijper, ... Molecular & Cellular Proteomics 6 (7), 1198-1214, 2007	689	2007
Next-generation proteomics: towards an integrative view of proteome dynamics AFM Altelaar, J Munoz, AJR Heck Nature Reviews Genetics 14 (1), 35-48, 2013	641	2013
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors BK Koo, M Spit, I Jordens, TY Low, DE Stange, M Van De Wetering, ... Nature 488 (7413), 665-669, 2012	639	2012
Investigation of intact protein complexes by mass spectrometry AJR Heck, RHH Van Den Heuvel Mass spectrometry reviews 23 (5), 368-389, 2004	631	2004
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+ 4’cell markers J Muñoz, DE Stange, AG Schepers, M Van De Wetering, BK Koo, ... The EMBO journal 31 (14), 3079-3091, 2012	579	2012
RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions B Wiedenheft, E van Duijn, JB Bultema, SP Waghmare, K Zhou, ... Proceedings of the National Academy of Sciences 108 (25), 10092-10097, 2011	547	2011
Structural basis for CRISPR RNA-guided DNA recognition by Cascade MM Jore, M Lundgren, E Van Duijn, JB Bultema, ER Westra, ... Nature structural & molecular biology 18 (5), 529, 2011	541	2011
Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics J Krijgsveld, RF Ketting, T Mahmoudi, J Johansen, M Artal-Sanz, ... Nature biotechnology 21 (8), 927-931, 2003	468	2003
Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice E de Boer, P Rodriguez, E Bonte, J Krijgsveld, E Katsantoni, A Heck, ... Proceedings of the National Academy of Sciences 100 (13), 7480-7485, 2003	460	2003
Ion mobility mass spectrometry of proteins and protein assemblies C Uetrecht, RJ Rose, E van Duijn, K Lorenzen, AJR Heck Chemical Society Reviews 39 (5), 1633-1655, 2010	439	2010
Complement is activated by IgG hexamers assembled at the cell surface CA Diebolder, FJ Beurskens, RN De Jong, RI Koning, K Strumane, ... Science 343 (6176), 1260-1263, 2014	432	2014
Imaging techniques for the study of chemical reaction dynamics AJR Heck, DW Chandler Annual Review of Physical Chemistry 46 (1), 335-372, 1995	413	1995

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