Makrina Totsika MSc PhD
Makrina Totsika MSc PhD
Vice-Chancellor's Senior Research Fellow, Group Leader in Infection and Immunity Program
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Global dissemination of a multidrug resistant Escherichia coli clone
NK Petty, NLB Zakour, M Stanton-Cook, E Skippington, M Totsika, ...
Proceedings of the National Academy of Sciences 111 (15), 5694-5699, 2014
Host–pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection
TJ Hannan, M Totsika, KJ Mansfield, KH Moore, MA Schembri, ...
FEMS microbiology reviews 36 (3), 616-648, 2012
DSB proteins and bacterial pathogenicity
B Heras, SR Shouldice, M Totsika, MJ Scanlon, MA Schembri, JL Martin
Nature Reviews Microbiology 7 (3), 215-225, 2009
Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection
GC Ulett, M Totsika, K Schaale, AJ Carey, MJ Sweet, MA Schembri
Current opinion in microbiology 16 (1), 100-107, 2013
Discovery of an archetypal protein transport system in bacterial outer membranes
J Selkrig, K Mosbahi, CT Webb, MJ Belousoff, AJ Perry, TJ Wells, F Morris, ...
Nature structural & molecular biology 19 (5), 506-510, 2012
Insights into a multidrug resistant Escherichia coli pathogen of the globally disseminated ST131 lineage: genome analysis and virulence mechanisms
M Totsika, SA Beatson, S Sarkar, MD Phan, NK Petty, N Bachmann, ...
PloS one 6 (10), e26578, 2011
UpaG, a new member of the trimeric autotransporter family of adhesins in uropathogenic Escherichia coli
J Valle, AN Mabbett, GC Ulett, A Toledo-Arana, K Wecker, M Totsika, ...
Journal of bacteriology 190 (12), 4147-4161, 2008
Chaperone-usher fimbriae of Escherichia coli
DJ Wurpel, SA Beatson, M Totsika, NK Petty, MA Schembri
PloS one 8 (1), e52835, 2013
Uropathogenic Escherichia coli mediated urinary tract infection
M Totsika, D Gomes Moriel, A Idris, B A Rogers, D J Wurpel, MD Phan, ...
Current drug targets 13 (11), 1386-1399, 2012
Virulence properties of asymptomatic bacteriuria Escherichia coli
AN Mabbett, GC Ulett, RE Watts, JJ Tree, M Totsika, YO Cheryl-lynn, ...
International Journal of Medical Microbiology 299 (1), 53-63, 2009
The serum resistome of a globally disseminated multidrug resistant uropathogenic Escherichia coli clone
MD Phan, KM Peters, S Sarkar, SW Lukowski, LP Allsopp, DG Moriel, ...
PLoS Genet 9 (10), e1003834, 2013
A FimH Inhibitor Prevents Acute Bladder Infection and Treats Chronic Cystitis Caused by Multidrug-Resistant Uropathogenic Escherichia coli ST131
M Totsika, M Kostakioti, TJ Hannan, M Upton, SA Beatson, JW Janetka, ...
The Journal of infectious diseases 208 (6), 921-928, 2013
The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping
B Heras, M Totsika, KM Peters, JJ Paxman, CL Gee, RJ Jarrott, ...
Proceedings of the National Academy of Sciences 111 (1), 457-462, 2014
Sortase A: an ideal target for anti-virulence drug development
S Cascioferro, M Totsika, D Schillaci
Microbial pathogenesis 77, 105-112, 2014
UpaH is a newly identified autotransporter protein that contributes to biofilm formation and bladder colonization by uropathogenic Escherichia coli CFT073
LP Allsopp, M Totsika, JJ Tree, GC Ulett, AN Mabbett, TJ Wells, B Kobe, ...
Infection and immunity 78 (4), 1659-1669, 2010
Structure and function of DsbA, a key bacterial oxidative folding catalyst
SR Shouldice, B Heras, PM Walden, M Totsika, MA Schembri, JL Martin
Antioxidants & redox signaling 14 (9), 1729-1760, 2011
Demonstration of regulatory cross-talk between P fimbriae and type 1 fimbriae in uropathogenic Escherichia coli
NJ Holden, M Totsika, E Mahler, AJ Roe, K Catherwood, K Lindner, ...
Microbiology 152 (4), 1143-1153, 2006
Innate transcriptional networks activated in bladder in response to uropathogenic Escherichia coli drive diverse biological pathways and rapid synthesis of IL-10 for defense …
BL Duell, AJ Carey, CK Tan, X Cui, RI Webb, M Totsika, MA Schembri, ...
The Journal of Immunology 188 (2), 781-792, 2012
Contribution of siderophore systems to growth and urinary tract colonization of asymptomatic bacteriuria Escherichia coli
RE Watts, M Totsika, VL Challinor, AN Mabbett, GC Ulett, JJ De Voss, ...
Infection and immunity 80 (1), 333-344, 2012
The complete genome sequence of Escherichia coli EC958: a high quality reference sequence for the globally disseminated multidrug resistant E. coli O25b: H4-ST131 clone
BM Forde, NLB Zakour, M Stanton-Cook, MD Phan, M Totsika, KM Peters, ...
PloS one 9 (8), e104400, 2014
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