| Low molecular weight amidoximes that act as potent inhibitors of lysine-specific demethylase 1 S Hazeldine, B Pachaiyappan, N Steinbergs, S Nowotarski, AS Hanson, ... Journal of medicinal chemistry 55 (17), 7378-7391, 2012 | 82 | 2012 |
| Antibacterial diamines targeting bacterial membranes B Wang, B Pachaiyappan, JD Gruber, MG Schmidt, YM Zhang, PM Woster Journal of medicinal chemistry 59 (7), 3140-3151, 2016 | 68 | 2016 |
| Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9 AV Maganti, B Maier, SA Tersey, ML Sampley, AL Mosley, S Özcan, ... Journal of Biological Chemistry 290 (15), 9812-9822, 2015 | 52 | 2015 |
| Structure–activity study for (bis) ureidopropyl-and (bis) thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures SL Nowotarski, B Pachaiyappan, SL Holshouser, CJ Kutz, Y Li, Y Huang, ... Bioorganic & medicinal chemistry 23 (7), 1601-1612, 2015 | 52 | 2015 |
| Design of small molecule epigenetic modulators B Pachaiyappan, PM Woster Bioorganic & medicinal chemistry letters 24 (1), 21-32, 2014 | 42 | 2014 |
| Interrogating alkyl and arylalkylpolyamino (bis) urea and (bis) thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum … BK Verlinden, M De Beer, B Pachaiyappan, E Besaans, WA Andayi, ... Bioorganic & medicinal chemistry 23 (16), 5131-5143, 2015 | 28 | 2015 |
| Molecular modeling, synthesis, and activity studies of novel biaryl and fused-ring BACE1 inhibitors SR Chirapu, B Pachaiyappan, HF Nural, X Cheng, H Yuan, DC Lankin, ... Bioorganic & medicinal chemistry letters 19 (1), 264-274, 2009 | 22 | 2009 |
| Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid H Lee, HV Le, R Wu, E Doud, R Sanishvili, JF Kellie, PD Compton, ... ACS chemical biology 10 (9), 2087-2098, 2015 | 17 | 2015 |
| A novel method for the synthesis of highly functionalized 3, 4-dihydropyrimidin-2 (1H)-ones through the 1, 4-addition on pyrimidin-2 (1H)-ones P Shanmugam, P Boobalan, PT Perumal Tetrahedron 63 (49), 12215-12219, 2007 | 12 | 2007 |
| Structure-and Ligand-Based Modeling of Beta-Secretase 1 (BACE1) Inhibitors B Pachaiyappan University of Illinois at Chicago, 2011 | 2 | 2011 |
| Corrigendum to" Structure-activity study for (bis) ureidopropyl-and (bis) thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures"[Bioorg … SL Nowotarski, B Pachaiyappan, SL Holshouser, CJ Kutz, Y Li, Y Huang, ... Bioorganic & medicinal chemistry 26 (12), 3728-3729, 2018 | 1 | 2018 |
| New Antibacterial Agents must, but Easy-to-Implement Assays First B Pachaiyappan Biochemistry and Analytical Biochemistry 4 (3), 1, 2015 | | 2015 |
| Discovery of a novel class of potent, broad-spectrum antibacterial agents containing bis-thioureas and bis-ureas B Pachaiyappan, B Wang, YM Zhang, PM Woster ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014 | | 2014 |
| Design, synthesis, and biological activities of novel oligoamines containing 3-5-3 linkers as epigenetic modulators B Pachaiyappan, SL Nowotarski, M Sokolosky, SL Holshouser, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 246, 2013 | | 2013 |
| Design of small molecule epigenetic modulators based on the polyamine backbone B Pachaiyappan, I Kumarasinge, S Holshouser, M Sokolosky, C Kutz, ... FEBS JOURNAL 280, 574-575, 2013 | | 2013 |
| Design, synthesis, and testing of novel histone demethylase inhibitors as epigenetic modulators B Pachaiyappan, SK Sharma, RJ Beattie, A Hanson, S Hazeldine, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 243, 2012 | | 2012 |
| COMP 344-Molecular modeling, synthesis and activity studies of inhibitors targeting Alzheimer's disease beta-secretase (BACE1) B Pachaiyappan, SR Chirapu, Z Zhong, H Yuan, SO Abdul-Hay, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 236, 2008 | | 2008 |
| Docking study of two Pin1 inhibitors into the catalytic site of Pin1 B Pachaiyappan, XJ Wang, FA Etzkorn ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 230, U590-U591, 2005 | | 2005 |
| Novel LSD1 Inhibitors Display Selective Cytotoxicity in Breast Cancer Cells and Inhibit 3D Growth ML Sokolosky, SL Holshouser, B Pachaiyappan, SK Sharma, PM Woster | | |
Yi HuangUniversity of Iowa Carver College of MedicineVerified email at uiowa.edu
