| QuPath: Open source software for digital pathology image analysis P Bankhead, MB Loughrey, JA Fernández, Y Dombrowski, DG McArt, ... Scientific reports 7 (1), 1-7, 2017 | 4617 | 2017 |
| Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning K Sirinukunwattana, E Domingo, SD Richman, KL Redmond, A Blake, ... Gut 70 (3), 544-554, 2021 | 175 | 2021 |
| Challenging the cancer molecular stratification dogma: intratumoral heterogeneity undermines consensus molecular subtypes and potential diagnostic value in colorectal cancer PD Dunne, DG McArt, CA Bradley, PG O'Reilly, HL Barrett, R Cummins, ... Clinical Cancer Research 22 (16), 4095-4104, 2016 | 161 | 2016 |
| The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer AK Najumudeen, F Ceteci, SK Fey, G Hamm, RT Steven, H Hall, ... Nature genetics 53 (1), 16-26, 2021 | 133 | 2021 |
| EphA2 expression is a key driver of migration and invasion and a poor prognostic marker in colorectal cancer PD Dunne, S Dasgupta, JK Blayney, DG McArt, KL Redmond, JA Weir, ... Clinical Cancer Research 22 (1), 230-242, 2016 | 132 | 2016 |
| AXL is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancer PD Dunne, DG McArt, JK Blayney, M Kalimutho, S Greer, T Wang, ... Clinical Cancer Research 20 (1), 164-175, 2014 | 114 | 2014 |
| ADAM17-dependent c-MET-STAT3 signaling mediates resistance to MEK inhibitors in KRAS mutant colorectal cancer S Van Schaeybroeck, M Kalimutho, PD Dunne, R Carson, W Allen, ... Cell reports 7 (6), 1940-1955, 2014 | 110 | 2014 |
| Fibroblast growth factor receptor 4 (FGFR4): a targetable regulator of drug resistance in colorectal cancer RC Turkington, DB Longley, WL Allen, L Stevenson, K McLaughlin, ... Cell death & disease 5 (2), e1046-e1046, 2014 | 106 | 2014 |
| Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification PD Dunne, M Alderdice, PG O'Reilly, AC Roddy, AMB McCorry, ... Nature communications 8 (1), 15657, 2017 | 90 | 2017 |
| QuPath: Open source software for digital pathology image analysis. Sci Rep. 2017; 7: 16878 P Bankhead, MB Loughrey, JA Fernández, Y Dombrowski, DG McArt, ... CHAPTER, 2022 | 85 | 2022 |
| DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response JEP Loughery, PD Dunne, KM O'Neill, RR Meehan, JR McDaid, ... Human molecular genetics 20 (16), 3241-3255, 2011 | 84 | 2011 |
| Validation of the systematic scoring of immunohistochemically stained tumour tissue microarrays using QuPath digital image analysis MB Loughrey, P Bankhead, HG Coleman, RS Hagan, S Craig, ... Histopathology 73 (2), 327-338, 2018 | 75 | 2018 |
| Stromal Cell PD-L1 Inhibits CD8+ T-cell Antitumor Immune Responses and Promotes Colon Cancer G O'Malley, O Treacy, K Lynch, SD Naicker, NA Leonard, P Lohan, ... Cancer immunology research 6 (11), 1426-1441, 2018 | 71 | 2018 |
| Transcriptional subtyping and CD8 immunohistochemistry identifies patients with stage II and III colorectal cancer with poor prognosis who benefit from adjuvant chemotherapy WL Allen, PD Dunne, S McDade, E Scanlon, M Loughrey, HG Coleman, ... JCO precision oncology 2, 1-15, 2018 | 66 | 2018 |
| Back to the future: routine morphological assessment of the tumour microenvironment is prognostic in stage II/III colon cancer in a large population‐based study SO Hynes, HG Coleman, PJ Kelly, S Irwin, RF O'Neill, RT Gray, ... Histopathology 71 (1), 12-26, 2017 | 65 | 2017 |
| Prospective patient stratification into robust cancer‐cell intrinsic subtypes from colorectal cancer biopsies M Alderdice, SD Richman, S Gollins, JP Stewart, C Hurt, R Adams, ... The Journal of pathology 245 (1), 19-28, 2018 | 64 | 2018 |
| Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification SO Kleeman, VH Koelzer, HJS Jones, EG Vazquez, H Davis, JE East, ... Gut 69 (6), 1092-1103, 2020 | 63 | 2020 |
| Gremlin1 plays a key role in kidney development and renal fibrosis RH Church, I Ali, M Tate, D Lavin, A Krishnakumar, HM Kok, ... American Journal of Physiology-Renal Physiology 312 (6), F1141-F1157, 2017 | 63 | 2017 |
| QuPath: Open source software for digital pathology image analysis. Sci Rep. 2017; 7 (1): 16878 P Bankhead, MB Loughrey, JA Fernandez, Y Dombrowski, DG McArt, ... Journal for ImmunoTherapy of Cancer (JITC) preprint. The copyright holder …, 0 | 59 | |
| Immune-derived PD-L1 gene expression defines a subgroup of stage II/III colorectal cancer patients with favorable prognosis who may be harmed by adjuvant chemotherapy PD Dunne, DG McArt, PG O'Reilly, HG Coleman, WL Allen, M Loughrey, ... Cancer immunology research 4 (7), 582-591, 2016 | 48 | 2016 |
