Marianne Koritzinsky
Marianne Koritzinsky
Verified email at uhnresearch.ca
Title
Cited by
Cited by
Year
Hypoxia signalling through mTOR and the unfolded protein response in cancer
BG Wouters, M Koritzinsky
Nature Reviews Cancer 8 (11), 851-864, 2008
8682008
ER stress‐regulated translation increases tolerance to extreme hypoxia and promotes tumor growth
M Bi, C Naczki, M Koritzinsky, D Fels, J Blais, N Hu, H Harding, I Novoa, ...
The EMBO journal 24 (19), 3470-3481, 2005
7452005
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2α
C Koumenis, C Naczki, M Koritzinsky, S Rastani, A Diehl, N Sonenberg, ...
Molecular and cellular biology 22 (21), 7405-7416, 2002
7192002
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
KMA Rouschop, T Van Den Beucken, L Dubois, H Niessen, J Bussink, ...
The Journal of clinical investigation 120 (1), 127-141, 2010
6642010
Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and-independent mechanisms and contributes to drug resistance
JT Erler, CJ Cawthorne, KJ Williams, M Koritzinsky, BG Wouters, C Wilson, ...
Molecular and cellular biology 24 (7), 2875-2889, 2004
4282004
Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and-independent mechanisms and contributes to drug resistance
JT Erler, CJ Cawthorne, KJ Williams, M Koritzinsky, BG Wouters, C Wilson, ...
Molecular and cellular biology 24 (7), 2875-2889, 2004
4222004
Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control
M Koritzinsky, MG Magagnin, T van den Beucken, R Seigneuric, ...
The EMBO journal 25 (5), 1114-1125, 2006
3462006
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance
N Chan, M Koritzinsky, H Zhao, R Bindra, PM Glazer, S Powell, ...
Cancer research 68 (2), 605-614, 2008
2822008
Hypoxia as a target for combined modality treatments
BG Wouters, SA Weppler, M Koritzinsky, W Landuyt, S Nuyts, J Theys, ...
European Journal of Cancer 38 (2), 240-257, 2002
2322002
Control of the hypoxic response through regulation of mRNA translation
BG Wouters, T van den Beucken, MG Magagnin, M Koritzinsky, D Fels, ...
Seminars in cell & developmental biology 16 (4-5), 487-501, 2005
1892005
Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy response
VE Zannella, A Dal Pra, H Muaddi, TD McKee, S Stapleton, J Sykes, ...
Clinical cancer research 19 (24), 6741-6750, 2013
1812013
Translational control of gene expression during hypoxia
T van den Beucken, M Koritzinsky, BG Wouters
Cancer biology & therapy 5 (7), 749-755, 2006
1632006
Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER
T Van Den Beucken, E Koch, K Chu, R Rupaimoole, P Prickaerts, ...
Nature communications 5 (1), 1-13, 2014
1552014
PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS
KM Rouschop, LJ Dubois, TG Keulers, T van den Beucken, P Lambin, ...
Proceedings of the National Academy of Sciences 110 (12), 4622-4627, 2013
1382013
The hypoxic proteome is influenced by gene-specific changes in mRNA translation
M Koritzinsky, R Seigneuric, MG Magagnin, T van den Beucken, ...
Radiotherapy and oncology 76 (2), 177-186, 2005
1232005
Autophagy is required during cycling hypoxia to lower production of reactive oxygen species
KMA Rouschop, CHMA Ramaekers, MBE Schaaf, TGH Keulers, ...
Radiotherapy and Oncology 92 (3), 411-416, 2009
1222009
Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3
H Mujcic, T Rzymski, KMA Rouschop, M Koritzinsky, M Milani, AL Harris, ...
Radiotherapy and Oncology 92 (3), 450-459, 2009
1082009
Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3
H Mujcic, A Nagelkerke, KMA Rouschop, S Chung, N Chaudary, PN Span, ...
Clinical Cancer Research 19 (22), 6126-6137, 2013
932013
Modulation of cell death in the tumor microenvironment
BG Wouters, M Koritzinsky, RK Chiu, J Theys, J Buijsen, P Lambin
Seminars in radiation oncology 13 (1), 31-41, 2003
882003
Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium
EO Pettersen, P Ebbesen, RG Gieling, KJ Williams, L Dubois, P Lambin, ...
Journal of enzyme inhibition and medicinal chemistry 30 (5), 689-721, 2015
842015
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