|An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting|
L Cai, SB Rothbart, R Lu, B Xu, WY Chen, A Tripathy, S Rockowitz, ...
Molecular cell 49 (3), 571-582, 2013
|Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia|
B Xu, DM On, A Ma, T Parton, KD Konze, SG Pattenden, DF Allison, L Cai, ...
Blood, The Journal of the American Society of Hematology 125 (2), 346-357, 2015
|Targeting EZH2 and PRC2 dependence as novel anticancer therapy|
B Xu, KD Konze, J Jin, GG Wang
Experimental hematology 43 (8), 698-712, 2015
|NUP98–PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function|
SM Gough, F Lee, F Yang, RL Walker, YJ Zhu, M Pineda, M Onozawa, ...
Cancer discovery 4 (5), 564-577, 2014
|The chromatin remodeler BPTF activates a stemness gene-expression program essential for the maintenance of adult hematopoietic stem cells|
B Xu, L Cai, JM Butler, D Chen, X Lu, DF Allison, R Lu, S Rafii, JS Parker, ...
Stem cell reports 10 (3), 675-683, 2018
|Discovery of selective inhibitors for lysine methyltransferases EZH2/EZH1 and SETD8|
A Ma, B Xu, D On, W Yu, K Konze, K Butler, F Li, M Vedadi, P Brown, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015
|NUP98-PHF23 is a chromatin modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD domain histone reader function.|
SM Gough, FY Fan Lee, RL Walker, YJ Zhu, M Pineda, M Onozawa, ...