| Targeting TGF-β mediated SMAD signaling for the prevention of fibrosis KL Walton, KE Johnson, CA Harrison Frontiers in pharmacology 8, 461, 2017 | 489 | 2017 |
| Elevated expression of activins promotes muscle wasting and cachexia JL Chen, KL Walton, CE Winbanks, KT Murphy, RE Thomson, Y Makanji, ... The FASEB Journal 28 (4), 1711-1723, 2014 | 221 | 2014 |
| Prodomains regulate the synthesis, extracellular localisation and activity of TGF-β superfamily ligands CA Harrison, SL Al-Musawi, KL Walton Growth factors 29 (5), 174-186, 2011 | 150 | 2011 |
| Structural basis for potency differences between GDF8 and GDF11 RG Walker, M Czepnik, EJ Goebel, JC McCoy, A Vujic, M Cho, J Oh, ... BMC biology 15, 1-22, 2017 | 121 | 2017 |
| Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease JL Chen, KL Walton, A Hagg, TD Colgan, K Johnson, H Qian, ... Proceedings of the National Academy of Sciences 114 (26), E5266-E5275, 2017 | 118 | 2017 |
| New insights into the mechanisms of activin action and inhibition KL Walton, Y Makanji, CA Harrison Molecular and cellular endocrinology 359 (1-2), 2-12, 2012 | 113 | 2012 |
| Two distinct regions of latency-associated peptide coordinate stability of the latent transforming growth factor-β1 complex KL Walton, Y Makanji, J Chen, MC Wilce, KL Chan, DM Robertson, ... Journal of biological chemistry 285 (22), 17029-17037, 2010 | 110 | 2010 |
| A common biosynthetic pathway governs the dimerization and secretion of inhibin and related transforming growth factor β (TGFβ) ligands KL Walton, Y Makanji, MC Wilce, KL Chan, DM Robertson, CA Harrison Journal of Biological Chemistry 284 (14), 9311-9320, 2009 | 106 | 2009 |
| Hormonal regulation of sertoli cell micro-RNAs at spermiation PK Nicholls, CA Harrison, KL Walton, RI McLachlan, L O'Donnell, ... Endocrinology 152 (4), 1670-1683, 2011 | 96 | 2011 |
| Differential effects of IL6 and activin A in the development of cancer-associated cachexia JL Chen, KL Walton, H Qian, TD Colgan, A Hagg, MJ Watt, CA Harrison, ... Cancer research 76 (18), 5372-5382, 2016 | 91 | 2016 |
| Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice CE Winbanks, KT Murphy, BC Bernardo, H Qian, Y Liu, PV Sepulveda, ... Science translational medicine 8 (348), 348ra98-348ra98, 2016 | 83 | 2016 |
| Activin signaling regulates Sertoli cell differentiation and function PK Nicholls, PG Stanton, JL Chen, JS Olcorn, JT Haverfield, H Qian, ... Endocrinology 153 (12), 6065-6077, 2012 | 80 | 2012 |
| The TGF-β signalling network in muscle development, adaptation and disease JL Chen, TD Colgan, KL Walton, P Gregorevic, CA Harrison Growth Factors and Cytokines in Skeletal Muscle Development, Growth …, 2016 | 78 | 2016 |
| The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma R Coulson, SH Liew, AA Connelly, NS Yee, S Deb, B Kumar, AC Vargas, ... Oncotarget 8 (12), 18640, 2017 | 76 | 2017 |
| Development of novel activin-targeted therapeutics JL Chen, KL Walton, SL Al-Musawi, EK Kelly, H Qian, M La, L Lu, ... Molecular Therapy 23 (3), 434-444, 2015 | 66 | 2015 |
| BMP15 mutations associated with primary ovarian insufficiency reduce expression, activity, or synergy with GDF9 LC Patiño, KL Walton, TD Mueller, KE Johnson, W Stocker, D Richani, ... The Journal of Clinical Endocrinology & Metabolism 102 (3), 1009-1019, 2017 | 64 | 2017 |
| Inhibin B Is a More Potent Suppressor of Rat Follicle-Stimulating Hormone Release than Inhibin A in Vitro and in Vivo Y Makanji, PD Temple-Smith, KL Walton, CA Harrison, DM Robertson Endocrinology 150 (10), 4784-4793, 2009 | 60 | 2009 |
| Suppression of inhibin A biological activity by alterations in the binding site for betaglycan Y Makanji, KL Walton, MC Wilce, KL Chan, DM Robertson, CA Harrison Journal of biological chemistry 283 (24), 16743-16751, 2008 | 58 | 2008 |
| New insights into the genetic basis of premature ovarian insufficiency: novel causative variants and candidate genes revealed by genomic sequencing S Jaillard, K Bell, L Akloul, K Walton, K McElreavy, WA Stocker, ... Maturitas 141, 9-19, 2020 | 54 | 2020 |
| Activation of Latent Human GDF9 by a Single Residue Change (Gly391Arg) in the Mature Domain CM Simpson, PG Stanton, KL Walton, KL Chan, LJ Ritter, RB Gilchrist, ... Endocrinology 153 (3), 1301-1310, 2012 | 54 | 2012 |
