Direct evidence for microdomain-specific localization and remodeling of functional L-type calcium channels in rat and human atrial myocytes AV Glukhov, M Balycheva, JL Sanchez-Alonso, Z Ilkan, A Alvarez-Laviada, ... Circulation 132 (25), 2372-2384, 2015 | 93 | 2015 |
Evidence for shear-mediated Ca2+ entry through mechanosensitive cation channels in human platelets and a megakaryocytic cell line Z Ilkan, JR Wright, AH Goodall, JM Gibbins, CI Jones, MP Mahaut-Smith Journal of Biological Chemistry 292 (22), 9204-9217, 2017 | 87 | 2017 |
The Ca2+-gated channel TMEM16A amplifies capillary pericyte contraction and reduces cerebral blood flow after ischemia N Korte, Z Ilkan, CL Pearson, T Pfeiffer, P Singhal, JR Rock, H Sethi, ... The Journal of clinical investigation 132 (9), 2022 | 55 | 2022 |
Intra-tracheal gene delivery of aerosolized SERCA2a to the lung suppresses ventricular arrhythmias in a model of pulmonary arterial hypertension B Strauss, Y Sassi, C Bueno-Beti, Z Ilkan, N Raad, M Cacheux, ... Journal of molecular and cellular cardiology 127, 20-30, 2019 | 26 | 2019 |
The mitochondrial translocator protein and the emerging link between oxidative stress and arrhythmias in the diabetic heart Z Ilkan, FG Akar Frontiers in Physiology 9, 416297, 2018 | 26 | 2018 |
Cardiomyocyte-specific STIM1 (stromal interaction molecule 1) depletion in the adult heart promotes the development of arrhythmogenic discordant alternans M Cacheux, B Strauss, N Raad, Z Ilkan, J Hu, L Benard, S Feske, JS Hulot, ... Circulation: Arrhythmia and Electrophysiology 12 (11), e007382, 2019 | 25 | 2019 |
P2X1 receptors amplify Fcγriia-induced Ca2+ increases and functional responses in human platelets Z Ilkan, S Watson, SP Watson, MP Mahaut-Smith Thrombosis and haemostasis 118 (02), 369-380, 2018 | 19 | 2018 |
Arrhythmia mechanism and dynamics in a humanized mouse model of inherited cardiomyopathy caused by phospholamban R14del mutation N Raad, P Bittihn, M Cacheux, D Jeong, Z Ilkan, D Ceholski, ... Circulation 144 (6), 441-454, 2021 | 17 | 2021 |
The pharmacology of the TMEM16A channel: therapeutic opportunities R Al-Hosni, Z Ilkan, E Agostinelli, P Tammaro Trends in Pharmacological Sciences 43 (9), 712-725, 2022 | 15 | 2022 |
Atrial AMP-activated protein kinase is critical for prevention of dysregulation of electrical excitability and atrial fibrillation KN Su, Y Ma, M Cacheux, Z Ilkan, N Raad, GK Muller, X Wu, N Guerrera, ... JCI insight 7 (8), 2022 | 10 | 2022 |
Optical action potential mapping in acute models of ischemia–reperfusion injury: Probing the arrhythmogenic role of the mitochondrial translocator protein Z Ilkan, B Strauss, C Campana, FG Akar Experimental Models of Cardiovascular Diseases: Methods and Protocols, 133-143, 2018 | 8 | 2018 |
OP16 Hydrogen sulfide inhibits human platelet aggregation Z Ilkan, F Mustafa, G Apostoli, A Solomon, M Whiteman, M Emerson Nitric Oxide 31, S26, 2013 | 6 | 2013 |
Immobilization of nonactivated unfixed platelets for real-time single-cell analysis AP Bye, Z Ilkan, AJ Unsworth, CI Jones Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives …, 2018 | 2 | 2018 |
thrombus formation under flow is inhibited by the mechanosensitive cation channel blockers GsMTx-4 peptide and gadolinium chloride Z Ilkan, JR Wright, L Francescut, AH Goodall, MP Mahaut-Smith Circulation 132 (suppl_3), A11593-A11593, 2015 | 2 | 2015 |
Inhibitory regulation of platelets by hydrogen sulphide M Emerson, Z Ilkan, F Mustafa, A Solomon, ME Wood, M Whiteman Nitric Oxide, S14-S15, 2015 | 1 | 2015 |
Distinct distribution of functional calcium channels revealed by super-resolution scanning patch-clamp in adult rat atrial cardiomyocytes AV Glukhov, M Balycheva, S Schobesberger, Z Ilkan, A Bhargava, ... Circulation 128 (suppl_22), A10467-A10467, 2013 | 1 | 2013 |
New insights into the molecular basis of allosteric activation of the TMEM16A channel and consequences for the control of vascular tone R Al Hosni, E Agostinelli, Z Ilkan, LF Scofano, K Acheson, A MacDonald, ... Biophysical Journal 122 (3), 458a, 2023 | | 2023 |
TMEM16A channel is a key regulator of cerebral blood flow at the capillary level Z Ilkan, N Korte, C Pearson, T Pfeiffer, P Singhal, D Attwell, P Tammaro Biophysical Journal 121 (3), 176a, 2022 | | 2022 |
B-PO04-006 CARDIAC SPECIFIC TSPO GENE SILENCING IMPROVES ELECTRICAL REMODELING AND POST-ISCHEMIC ARRHYTHMIAS IN HYPERTROPHIED HEARTS M Cacheux, A Tieu, Z Ilkan, P Jirak, LJ Motloch, B O'Rourke, FG Akar Heart Rhythm 18 (8), S282, 2021 | | 2021 |
Cardiomyocyte-Specific STIM1 Depletion in the Adult Heart Promotes Arrhythmogenic Discordant Alternans M Cacheux, Z Ilkan, JS Hulot, FG Akar Circulation 140 (Suppl_1), A14678-A14678, 2019 | | 2019 |