|High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever|
DH Libraty, PR Young, D Pickering, TP Endy, S Kalayanarooj, S Green, ...
The Journal of infectious diseases 186 (8), 1165-1168, 2002
|An antigen capture enzyme-linked immunosorbent assay reveals high levels of the dengue virus protein NS1 in the sera of infected patients|
PR Young, PA Hilditch, C Bletchly, W Halloran
Journal of clinical microbiology 38 (3), 1053-1057, 2000
|The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity|
M Beltramello, KL Williams, CP Simmons, A Macagno, L Simonelli, ...
Cell host & microbe 8 (3), 271-283, 2010
|Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replication|
JM MACKENZIE, MK JONES, PR YOUNG
Virology 220 (1), 232-240, 1996
|The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker|
DA Muller, PR Young
Antiviral research 98 (2), 192-208, 2013
|Retroviral invasion of the koala genome|
RE Tarlinton, J Meers, PR Young
Nature 442 (7098), 79-81, 2006
|Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors|
D Leung, K Schroder, H White, NX Fang, MJ Stoermer, G Abbenante, ...
Journal of Biological Chemistry 276 (49), 45762-45771, 2001
|Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity|
N Modhiran, D Watterson, DA Muller, AK Panetta, DP Sester, L Liu, ...
Science translational medicine 7 (304), 304ra142-304ra142, 2015
|Dengue virus nonstructural protein 1 is expressed in a glycosyl‐phosphatidylinositol‐linked form that is capable of signal transduction|
MG Jacobs, PJ Robinson, C Bletchly, JM Mackenzie, PR Young
The FASEB Journal 14 (11), 1603-1610, 2000
|Maternal antibody and viral factors in the pathogenesis of dengue virus in infants|
CP Simmons, TNB Chau, TT Thuy, NM Tuan, DM Hoang, NT Thien, ...
The Journal of infectious diseases 196 (3), 416-424, 2007
|The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach|
SR Fry, M Meyer, MG Semple, CP Simmons, SD Sekaran, JX Huang, ...
PLoS Negl Trop Dis 5 (6), e1199, 2011
|Wolbachia-mediated resistance to dengue virus infection and death at the cellular level|
FD Frentiu, J Robinson, PR Young, EA McGraw, SL O'Neill
PloS one 5 (10), e13398, 2010
|Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency|
RS Harrison, NE Shepherd, HN Hoang, G Ruiz-Gómez, TA Hill, ...
Proceedings of the National Academy of Sciences 107 (26), 11686-11691, 2010
|Use of recombinant fusion proteins and monoclonal antibodies to define linear and discontinuous antigenic sites on the dengue virus envelope glycoprotein|
F Megret, JP Hugnot, A Falconar, MK Gentry, DM Morens, JM Murray, ...
Virology 187 (2), 480-491, 1992
|Kinetics of plasma viremia and soluble nonstructural protein 1 concentrations in dengue: differential effects according to serotype and immune status|
HTL Duyen, TV Ngoc, DT Ha, VTT Hang, NTT Kieu, PR Young, JJ Farrar, ...
Journal of Infectious Diseases 203 (9), 1292-1300, 2011
|The role of histidine residues in low-pH-mediated viral membrane fusion|
T Kampmann, DS Mueller, AE Mark, PR Young, B Kobe
Structure 14 (10), 1481-1487, 2006
|Real-time reverse transcriptase PCR for the endogenous koala retrovirus reveals an association between plasma viral load and neoplastic disease in koalas|
R Tarlinton, J Meers, J Hanger, P Young
Journal of general virology 86 (3), 783-787, 2005
|Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation|
G Robin, K Chappell, MJ Stoermer, SH Hu, PR Young, DP Fairlie, ...
Journal of molecular biology 385 (5), 1568-1577, 2009
|Clinical and laboratory diagnosis of dengue virus infection|
DA Muller, ACI Depelsenaire, PR Young
The Journal of infectious diseases 215 (suppl_2), S89-S95, 2017
|Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease|
TA Nall, KJ Chappell, MJ Stoermer, NX Fang, JDA Tyndall, PR Young, ...
Journal of Biological Chemistry 279 (47), 48535-48542, 2004