Paul Young
Paul Young
Professor of Virology, University of Queensland
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High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever
DH Libraty, PR Young, D Pickering, TP Endy, S Kalayanarooj, S Green, ...
The Journal of infectious diseases 186 (8), 1165-1168, 2002
An antigen capture enzyme-linked immunosorbent assay reveals high levels of the dengue virus protein NS1 in the sera of infected patients
PR Young, PA Hilditch, C Bletchly, W Halloran
Journal of clinical microbiology 38 (3), 1053-1057, 2000
The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity
M Beltramello, KL Williams, CP Simmons, A Macagno, L Simonelli, ...
Cell host & microbe 8 (3), 271-283, 2010
Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replication
Virology 220 (1), 232-240, 1996
The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker
DA Muller, PR Young
Antiviral research 98 (2), 192-208, 2013
Retroviral invasion of the koala genome
RE Tarlinton, J Meers, PR Young
Nature 442 (7098), 79-81, 2006
Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors
D Leung, K Schroder, H White, NX Fang, MJ Stoermer, G Abbenante, ...
Journal of Biological Chemistry 276 (49), 45762-45771, 2001
Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity
N Modhiran, D Watterson, DA Muller, AK Panetta, DP Sester, L Liu, ...
Science translational medicine 7 (304), 304ra142-304ra142, 2015
Dengue virus nonstructural protein 1 is expressed in a glycosyl‐phosphatidylinositol‐linked form that is capable of signal transduction
MG Jacobs, PJ Robinson, C Bletchly, JM Mackenzie, PR Young
The FASEB Journal 14 (11), 1603-1610, 2000
Maternal antibody and viral factors in the pathogenesis of dengue virus in infants
CP Simmons, TNB Chau, TT Thuy, NM Tuan, DM Hoang, NT Thien, ...
The Journal of infectious diseases 196 (3), 416-424, 2007
The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach
SR Fry, M Meyer, MG Semple, CP Simmons, SD Sekaran, JX Huang, ...
PLoS Negl Trop Dis 5 (6), e1199, 2011
Wolbachia-mediated resistance to dengue virus infection and death at the cellular level
FD Frentiu, J Robinson, PR Young, EA McGraw, SL O'Neill
PloS one 5 (10), e13398, 2010
Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency
RS Harrison, NE Shepherd, HN Hoang, G Ruiz-Gómez, TA Hill, ...
Proceedings of the National Academy of Sciences 107 (26), 11686-11691, 2010
Use of recombinant fusion proteins and monoclonal antibodies to define linear and discontinuous antigenic sites on the dengue virus envelope glycoprotein
F Megret, JP Hugnot, A Falconar, MK Gentry, DM Morens, JM Murray, ...
Virology 187 (2), 480-491, 1992
Kinetics of plasma viremia and soluble nonstructural protein 1 concentrations in dengue: differential effects according to serotype and immune status
HTL Duyen, TV Ngoc, DT Ha, VTT Hang, NTT Kieu, PR Young, JJ Farrar, ...
Journal of Infectious Diseases 203 (9), 1292-1300, 2011
The role of histidine residues in low-pH-mediated viral membrane fusion
T Kampmann, DS Mueller, AE Mark, PR Young, B Kobe
Structure 14 (10), 1481-1487, 2006
Real-time reverse transcriptase PCR for the endogenous koala retrovirus reveals an association between plasma viral load and neoplastic disease in koalas
R Tarlinton, J Meers, J Hanger, P Young
Journal of general virology 86 (3), 783-787, 2005
Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation
G Robin, K Chappell, MJ Stoermer, SH Hu, PR Young, DP Fairlie, ...
Journal of molecular biology 385 (5), 1568-1577, 2009
Clinical and laboratory diagnosis of dengue virus infection
DA Muller, ACI Depelsenaire, PR Young
The Journal of infectious diseases 215 (suppl_2), S89-S95, 2017
Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease
TA Nall, KJ Chappell, MJ Stoermer, NX Fang, JDA Tyndall, PR Young, ...
Journal of Biological Chemistry 279 (47), 48535-48542, 2004
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