Lachlan Harris
Lachlan Harris
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Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population
L Harris, P Rigo, T Stiehl, ZB Gaber, SHL Austin, M del Mar Masdeu, ...
Cell stem cell 28 (5), 863-876. e6, 2021
Long-term self-renewing stem cells in the adult mouse hippocampus identified by intravital imaging
S Bottes, BN Jaeger, GA Pilz, DJ Jörg, JD Cole, M Kruse, L Harris, ...
Nature neuroscience 24 (2), 225-233, 2021
NFIB mediates BRN2 driven melanoma cell migration and invasion through regulation of EZH2 and MITF
ME Fane, Y Chhabra, DEJ Hollingsworth, JL Simmons, L Spoerri, TG Oh, ...
EBioMedicine 16, 63-75, 2017
NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development
M Piper, G Barry, TJ Harvey, R McLeay, AG Smith, L Harris, S Mason, ...
Journal of Neuroscience 34 (8), 2921-2930, 2014
Nuclear factor one transcription factors: divergent functions in developmental versus adult stem cell populations
L Harris, LA Genovesi, RM Gronostajski, BJ Wainwright, M Piper
Developmental dynamics 244 (3), 227-238, 2015
Familial Alzheimer’s disease mutations in PSEN1 lead to premature human stem cell neurogenesis
C Arber, C Lovejoy, L Harris, N Willumsen, A Alatza, JM Casey, G Lines, ...
Cell reports 34 (2), 2021
Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord
E Matuzelski, J Bunt, D Harkins, JWC Lim, RM Gronostajski, LJ Richards, ...
Developmental biology 432 (2), 286-297, 2017
Nuclear factor one transcription factors as epigenetic regulators in cancer
M Fane, L Harris, AG Smith, M Piper
International Journal of Cancer 140 (12), 2634-2641, 2017
Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum
M Piper, L Harris, G Barry, YHE Heng, C Plachez, RM Gronostajski, ...
Journal of Comparative Neurology 519 (17), 3532-3548, 2011
NFIX regulates proliferation and migration within the murine SVZ neurogenic niche
YHE Heng, B Zhou, L Harris, T Harvey, A Smith, E Horne, B Martynoga, ...
Cerebral cortex 25 (10), 3758-3778, 2015
BrdU/EdU dual labeling to determine the cell-cycle dynamics of defined cellular subpopulations
L Harris, O Zalucki, M Piper
Journal of molecular histology 49, 229-234, 2018
Transcriptional regulation of intermediate progenitor cell generation during hippocampal development
L Harris, O Zalucki, I Gobius, H McDonald, J Osinki, TJ Harvey, A Essebier, ...
Development 143 (24), 4620-4630, 2016
Differential neuronal and glial expression of nuclear factor I proteins in the cerebral cortex of adult mice
KS Chen, L Harris, JWC Lim, TJ Harvey, M Piper, RM Gronostajski, ...
Journal of Comparative Neurology 525 (11), 2465-2483, 2017
Neurogenic differentiation by hippocampal neural stem and progenitor cells is biased by NFIX expression
L Harris, O Zalucki, O Clément, J Fraser, E Matuzelski, S Oishi, TJ Harvey, ...
Development 145 (3), dev155689, 2018
Insights into the biology and therapeutic applications of neural stem cells
L Harris, O Zalucki, M Piper, JIT Heng
Stem cells international 2016, 2016
Combined allelic dosage of Nfia and Nfib regulates cortical development
J Bunt, JM Osinski, JWC Lim, D Vidovic, Y Ye, O Zalucki, TR O’Connor, ...
Brain and neuroscience advances 1, 2398212817739433, 2017
Wnt/β-catenin signalling is dispensable for adult neural stem cell homeostasis and activation
SHL Austin, R Gabarró-Solanas, P Rigo, O Paun, L Harris, F Guillemot, ...
Development 148 (20), dev199629, 2021
Heterozygosity for nuclear factor one x affects hippocampal-dependent behaviour in mice
L Harris, C Dixon, K Cato, YHE Heng, ND Kurniawan, JFP Ullmann, ...
PloS one 8 (6), e65478, 2013
HES1, two programs: promoting the quiescence and proliferation of adult neural stem cells
L Harris, F Guillemot
Genes & development 33 (9-10), 479-481, 2019
Expansion of the lateral ventricles and ependymal deficits underlie the hydrocephalus evident in mice lacking the transcription factor NFIX
D Vidovic, L Harris, TJ Harvey, YHE Heng, AG Smith, J Osinski, J Hughes, ...
Brain research 1616, 71-87, 2015
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