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J. Perren Cobb, MD, FACS, FCCM
J. Perren Cobb, MD, FACS, FCCM
Keck Medicine of USC, Los Angeles, CA, USA
Verified email at usc.edu
Title
Cited by
Cited by
Year
Genomic responses in mouse models poorly mimic human inflammatory diseases
J Seok, HS Warren, AG Cuenca, MN Mindrinos, HV Baker, W Xu, ...
Proceedings of the National Academy of Sciences 110 (9), 3507-3512, 2013
30662013
Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction
RS Hotchkiss, PE Swanson, BD Freeman, KW Tinsley, JP Cobb, ...
Critical care medicine 27 (7), 1230-1251, 1999
17411999
A network-based analysis of systemic inflammation in humans
SE Calvano, W Xiao, DR Richards, RM Felciano, HV Baker, RJ Cho, ...
Nature 437 (7061), 1032-1037, 2005
16542005
A genomic storm in critically injured humans
W Xiao, MN Mindrinos, J Seok, J Cuschieri, AG Cuenca, H Gao, ...
Journal of Experimental Medicine 208 (13), 2581-2590, 2011
12422011
Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans
RS Hotchkiss, KW Tinsley, PE Swanson, RE Schmieg, JJ Hui, KC Chang, ...
The Journal of Immunology 166 (11), 6952-6963, 2001
12022001
Prevention of lymphocyte cell death in sepsis improves survival in mice
RS Hotchkiss, KW Tinsley, PE Swanson, KC Chang, JP Cobb, ...
Proceedings of the National Academy of Sciences 96 (25), 14541-14546, 1999
5831999
Inflammation and Host Response to Injury, Large Scale Collaborative Research Program. Genomic responses in mouse models poorly mimic human inflammatory diseases
J Seok, HS Warren, AG Cuenca, MN Mindrinos, HV Baker, W Xu, ...
Proc Natl Acad Sci USA 110 (9), 3507-3512, 2013
5472013
Depletion of dendritic cells, but not macrophages, in patients with sepsis
RS Hotchkiss, KW Tinsley, PE Swanson, MH Grayson, DF Osborne, ...
The Journal of immunology 168 (5), 2493-2500, 2002
5472002
Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis
RS Hotchkiss, PE Swanson, CM Knudson, KC Chang, JP Cobb, ...
The Journal of Immunology 162 (7), 4148-4156, 1999
5081999
Apoptosis in lymphoid and parenchymal cells during sepsis: findings in normal and T-and B-cell-deficient mice
RS Hotchkiss, PE Swanson, JP Cobb, A Jacobson, TG Buchman, IE Karl
Critical care medicine 25 (8), 1298-1307, 1997
4571997
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis
A Hinks, J Cobb, MC Marion, S Prahalad, M Sudman, J Bowes, P Martin, ...
Nature genetics 45 (6), 664-669, 2013
4452013
N omega-amino-L-arginine, an inhibitor of nitric oxide synthase, raises vascular resistance but increases mortality rates in awake canines challenged with endotoxin.
JP Cobb, C Natanson, WD Hoffman, RF Lodato, S Banks, CA Koev, ...
The Journal of experimental medicine 176 (4), 1175-1182, 1992
3041992
A prospective, randomized study comparing percutaneous with surgical tracheostomy in critically ill patients
BD Freeman, K Isabella, JP Cobb, WA Boyle III, RE Schmieg Jr, ...
Critical care medicine 29 (5), 926-930, 2001
3012001
Application of genome-wide expression analysis to human health and disease
JP Cobb, MN Mindrinos, C Miller-Graziano, SE Calvano, HV Baker, ...
Proceedings of the National Academy of Sciences 102 (13), 4801-4806, 2005
2672005
Rapid onset of intestinal epithelial and lymphocyte apoptotic cell death in patients with trauma and shock
RS Hotchkiss, RE Schmieg Jr, PE Swanson, BD Freeman, KW Tinsley, ...
Critical care medicine 28 (9), 3207-3217, 2000
2582000
Nitric oxide and septic shock
JP Cobb, RL Danner
Jama 275 (15), 1192-1196, 1996
2281996
Whole blood and leukocyte RNA isolation for gene expression analyses
RJ Feezor, HV Baker, M Mindrinos, D Hayden, CL Tannahill, ...
Physiological genomics 19 (3), 247-254, 2004
2052004
Nitric oxide regulates endotoxin-induced TNF-alpha production by human neutrophils.
AL Van Dervort, L Yan, PJ Madara, JP Cobb, RA Wesley, CC Corriveau, ...
Journal of immunology (Baltimore, Md.: 1950) 152 (8), 4102-4109, 1994
1751994
HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis
MJ Ombrello, EF Remmers, I Tachmazidou, A Grom, D Foell, JP Haas, ...
Proceedings of the National Academy of Sciences 112 (52), 15970-15975, 2015
1702015
Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications
MJ Ombrello, VL Arthur, EF Remmers, A Hinks, I Tachmazidou, AA Grom, ...
Annals of the rheumatic diseases 76 (5), 906-913, 2017
1652017
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