Functional genomic landscape of acute myeloid leukaemia JW Tyner, CE Tognon, D Bottomly, B Wilmot, SE Kurtz, SL Savage, ... Nature 562 (7728), 526-531, 2018 | 1058 | 2018 |
Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML JE Maxson, J Gotlib, DA Pollyea, AG Fleischman, A Agarwal, CA Eide, ... New England Journal of Medicine 368 (19), 1781-1790, 2013 | 610 | 2013 |
Evaluating gene expression in C57BL/6J and DBA/2J mouse striatum using RNA-Seq and microarrays D Bottomly, NAR Walter, JE Hunter, P Darakjian, S Kawane, KJ Buck, ... PloS one 6 (3), e17820, 2011 | 270 | 2011 |
Modeling host genetic regulation of influenza pathogenesis in the collaborative cross MT Ferris, DL Aylor, D Bottomly, AC Whitmore, LD Aicher, TA Bell, ... PLoS pathogens 9 (2), e1003196, 2013 | 221 | 2013 |
Identification of β-catenin binding regions in colon cancer cells using ChIP-Seq D Bottomly, SL Kyler, SK McWeeney, GS Yochum Nucleic acids research 38 (17), 5735-5745, 2010 | 183 | 2010 |
Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms H Zhang, S Savage, AR Schultz, D Bottomly, L White, E Segerdell, ... Nature communications 10 (1), 244, 2019 | 153 | 2019 |
Utilizing RNA-Seq data for de novo coexpression network inference OD Iancu, S Kawane, D Bottomly, R Searles, R Hitzemann, S McWeeney Bioinformatics 28 (12), 1592-1597, 2012 | 145 | 2012 |
Androgen receptor promotes ligand-independent prostate cancer progression through c-Myc upregulation L Gao, J Schwartzman, A Gibbs, R Lisac, R Kleinschmidt, B Wilmot, ... PloS one 8 (5), e63563, 2013 | 144 | 2013 |
Integrated analysis of patient samples identifies biomarkers for venetoclax efficacy and combination strategies in acute myeloid leukemia H Zhang, Y Nakauchi, T Köhnke, M Stafford, D Bottomly, R Thomas, ... Nature cancer 1 (8), 826-839, 2020 | 127 | 2020 |
Integrative analysis of drug response and clinical outcome in acute myeloid leukemia D Bottomly, N Long, AR Schultz, SE Kurtz, CE Tognon, K Johnson, M Abel, ... Cancer cell 40 (8), 850-864. e9, 2022 | 106 | 2022 |
Genes, behavior and next‐generation RNA sequencing R Hitzemann, D Bottomly, P Darakjian, N Walter, O Iancu, R Searles, ... Genes, Brain and Behavior 12 (1), 1-12, 2013 | 104 | 2013 |
Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice D Bottomly, MT Ferris, LD Aicher, E Rosenzweig, A Whitmore, DL Aylor, ... G3: Genes| Genomes| Genetics 2 (2), 213-221, 2012 | 96 | 2012 |
The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance SK Joshi, T Nechiporuk, D Bottomly, PD Piehowski, JA Reisz, ... Cancer cell 39 (7), 999-1014. e8, 2021 | 76 | 2021 |
Genomic landscape of neutrophilic leukemias of ambiguous diagnosis H Zhang, B Wilmot, D Bottomly, KHT Dao, E Stevens, CA Eide, V Khanna, ... Blood, The Journal of the American Society of Hematology 134 (11), 867-879, 2019 | 71 | 2019 |
Identification and prioritization of myeloid malignancy germline variants in a large cohort of adult patients with AML F Yang, N Long, T Anekpuritanang, D Bottomly, JC Savage, T Lee, ... Blood, The Journal of the American Society of Hematology 139 (8), 1208-1221, 2022 | 62 | 2022 |
Identification and characterization of tyrosine kinase nonreceptor 2 mutations in leukemia through integration of kinase inhibitor screening and genomic analysis JE Maxson, ML Abel, J Wang, X Deng, S Reckel, SB Luty, H Sun, ... Cancer research 76 (1), 127-138, 2016 | 40 | 2016 |
Comparison and validation of the 2022 European LeukemiaNet guidelines in acute myeloid leukemia CA Lachowiez, N Long, J Saultz, A Gandhi, LF Newell, B Hayes-Lattin, ... Blood Advances 7 (9), 1899-1909, 2023 | 33 | 2023 |
High throughput sequencing in mice: a platform comparison identifies a preponderance of cryptic SNPs NAR Walter, D Bottomly, T Laderas, MA Mooney, P Darakjian, RP Searles, ... BMC genomics 10, 1-11, 2009 | 28 | 2009 |
Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms SK Joshi, K Qian, WH Bisson, K Watanabe-Smith, A Huang, D Bottomly, ... Blood, The Journal of the American Society of Hematology 135 (24), 2159-2170, 2020 | 27 | 2020 |
Biomarkers predicting venetoclax sensitivity and strategies for venetoclax combination treatment H Zhang, B Wilmot, D Bottomly, SE Kurtz, CA Eide, A Damnernsawad, ... Blood 132, 175, 2018 | 24 | 2018 |