| Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer A Etzerodt, M Moulin, TK Doktor, M Delfini, N Mossadegh-Keller, ... Journal of Experimental Medicine 217 (4), 2020 | 216 | 2020 |
| CUGBP1 and MBNL1 preferentially bind to 3′ UTRs and facilitate mRNA decay A Masuda, HS Andersen, TK Doktor, T Okamoto, M Ito, BS Andresen, ... Scientific reports 2 (1), 209, 2012 | 216 | 2012 |
| Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans C Heintz, TK Doktor, A Lanjuin, CC Escoubas, Y Zhang, HJ Weir, S Dutta, ... Nature 541 (7635), 102-106, 2017 | 180 | 2017 |
| Seemingly neutral polymorphic variants may confer immunity to splicing-inactivating mutations: a synonymous SNP in exon 5 of MCAD protects from deleterious mutations in a … KB Nielsen, S Sørensen, L Cartegni, TJ Corydon, TK Doktor, ... The American Journal of Human Genetics 80 (3), 416-432, 2007 | 153 | 2007 |
| RNA-sequencing of a mouse-model of spinal muscular atrophy reveals tissue-wide changes in splicing of U12-dependent introns TK Doktor, Y Hua, HS Andersen, S Brøner, YH Liu, A Wieckowska, ... Nucleic acids research 45 (1), 395-416, 2017 | 108 | 2017 |
| Global identification of hnRNP A1 binding sites for SSO-based splicing modulation GH Bruun, TK Doktor, J Borch-Jensen, A Masuda, AR Krainer, K Ohno, ... BMC biology 14, 1-19, 2016 | 80 | 2016 |
| The deep intronic c.903+469T>C mutation in the MTRR gene creates an SF2/ASF binding exonic splicing enhancer, which leads to pseudoexon activation and … K Homolova, P Zavadakova, TK Doktor, LD Schroeder, V Kozich, ... Human mutation 31 (4), 437-444, 2010 | 77 | 2010 |
| DeepCLIP: predicting the effect of mutations on protein–RNA binding with deep learning AGB Grønning, TK Doktor, SJ Larsen, USS Petersen, LL Holm, GH Bruun, ... Nucleic acids research 48 (13), 7099-7118, 2020 | 76 | 2020 |
| SMN2 exon 7 splicing is inhibited by binding of hnRNP A1 to a common ESS motif that spans the 3′ splice site T Koed Doktor, LD Schroeder, A Vested, J Palmfeldt, HS Andersen, ... Human mutation 32 (2), 220-230, 2011 | 50 | 2011 |
| The ETFDH c.158A>G Variation Disrupts the Balanced Interplay of ESE‐ and ESS‐Binding Proteins thereby Causing Missplicing and Multiple Acyl‐CoA … RKJ Olsen, S Brøner, R Sabaratnam, TK Doktor, HS Andersen, GH Bruun, ... Human Mutation 35 (1), 86-95, 2014 | 35 | 2014 |
| The prevalent deep intronic c. 639+ 919 G> A GLA mutation causes pseudoexon activation and Fabry disease by abolishing the binding of hnRNPA1 and hnRNP A2/B1 to a splicing silencer B Palhais, M Dembic, R Sabaratnam, KS Nielsen, TK Doktor, GH Bruun, ... Molecular genetics and metabolism 119 (3), 258-269, 2016 | 33 | 2016 |
| The phenylalanine hydroxylase c. 30C> G synonymous variation (p. G10G) creates a common exonic splicing silencer SF Dobrowolski, HS Andersen, TK Doktor, BS Andresen Molecular genetics and metabolism 100 (4), 316-323, 2010 | 31 | 2010 |
| Splice-shifting oligonucleotide (SSO) mediated blocking of an exonic splicing enhancer (ESE) created by the prevalent c.903+469T>C MTRR mutation corrects … B Palhais, VS Præstegaard, R Sabaratnam, TK Doktor, S Lutz, P Burda, ... Nucleic acids research 43 (9), 4627-4639, 2015 | 30 | 2015 |
| A synonymous polymorphic variation in ACADM exon 11 affects splicing efficiency and may affect fatty acid oxidation GH Bruun, TK Doktor, BS Andresen Molecular genetics and metabolism 110 (1-2), 122-128, 2013 | 30 | 2013 |
| Pseudoexon activation in disease by non‐splice site deep intronic sequence variation—wild type pseudoexons constitute high‐risk sites in the human genome USS Petersen, TK Doktor, BS Andresen Human mutation 43 (2), 103-127, 2022 | 18 | 2022 |
| Next generation sequencing of RNA reveals novel targets of resveratrol with possible implications for Canavan disease M Dembic, HS Andersen, J Bastin, TK Doktor, TJ Corydon, JO Sass, ... Molecular Genetics and Metabolism 126 (1), 64-76, 2019 | 18 | 2019 |
| Blocking of an intronic splicing silencer completely rescues IKBKAP exon 20 splicing in familial dysautonomia patient cells GH Bruun, JMV Bang, LL Christensen, S Brøner, USS Petersen, B Guerra, ... Nucleic Acids Research 46 (15), 7938-7952, 2018 | 14 | 2018 |
| Identification of SRSF10 as a regulator of SMN2 ISS‐N1 SB Frederiksen, LL Holm, MR Larsen, TK Doktor, HS Andersen, ... Human mutation 42 (3), 246-260, 2021 | 13 | 2021 |
| Vulnerable exons, like ACADM exon 5, are highly dependent on maintaining a correct balance between splicing enhancers and silencers LL Holm, TK Doktor, MB Hansen, USS Petersen, BS Andresen Human Mutation 43 (2), 253-265, 2022 | 12 | 2022 |
| VEGFA-targeting miR-agshRNAs combine efficacy with specificity and safety for retinal gene therapy S Alsing, TK Doktor, AL Askou, EG Jensen, U Ahmadov, LS Kristensen, ... Molecular Therapy-Nucleic Acids 28, 58-76, 2022 | 9 | 2022 |
Brage S. AndresenProfessor Molekylær Biologi, Syddansk Universitet Verified email at bmb.sdu.dk
