| Relaxin family peptides and their receptors RAD Bathgate, ML Halls, ET van der Westhuizen, GE Callander, M Kocan, ... Physiological reviews 93 (1), 405-480, 2013 | 538 | 2013 |
| Quantification of ligand bias for clinically relevant β2-adrenergic receptor ligands: implications for drug taxonomy ET van der Westhuizen, B Breton, A Christopoulos, M Bouvier Molecular pharmacology 85 (3), 492-509, 2014 | 250 | 2014 |
| Amylin receptor phenotypes derived from human calcitonin receptor/RAMP coexpression exhibit pharmacological differences dependent on receptor isoform and host cell environment N Tilakaratne, G Christopoulos, ET Zumpe, SM Foord, PM Sexton Journal of Pharmacology and Experimental Therapeutics 294 (1), 61-72, 2000 | 196 | 2000 |
| Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist M Masureel, Y Zou, LP Picard, E van der Westhuizen, JP Mahoney, ... Nature chemical biology 14 (11), 1059-1066, 2018 | 167 | 2018 |
| Endogenous allosteric modulators of G protein–coupled receptors ET van der Westhuizen, C Valant, PM Sexton, A Christopoulos Journal of Pharmacology and Experimental Therapeutics 353 (2), 246-260, 2015 | 149 | 2015 |
| Relaxin family peptide receptors–former orphans reunite with their parent ligands to activate multiple signalling pathways ML Halls, ET van der Westhuizen, RAD Bathgate, RJ Summers British journal of pharmacology 150 (6), 677-691, 2007 | 134 | 2007 |
| Impedance Responses Reveal β2-Adrenergic Receptor Signaling Pluridimensionality and Allow Classification of Ligands with Distinct Signaling Profiles W Stallaert, JF Dorn, E van der Westhuizen, M Audet, M Bouvier PloS one 7 (1), e29420, 2012 | 121 | 2012 |
| The relaxin family peptide receptor 3 activates extracellular signal-regulated kinase 1/2 through a protein kinase C-dependent mechanism ET van der Westhuizen, TD Werry, PM Sexton, RJ Summers Molecular pharmacology 71 (6), 1618-1629, 2007 | 106 | 2007 |
| FSH-regulated gene expression profiles in ovarian tumours and normal ovaries S Chu, S Rushdi, ET Zumpe, P Mamers, DL Healy, T Jobling, HG Burger, ... Molecular human reproduction 8 (5), 426-433, 2002 | 105 | 2002 |
| Multiple ramp domains are required for generation of amylin receptor phenotype from the calcitonin receptor gene product ET Zumpe, N Tilakaratne, NJ Fraser, G Christopoulos, SM Foord, ... Biochemical and biophysical research communications 267 (1), 368-372, 2000 | 88 | 2000 |
| Relaxin family peptide receptors–from orphans to therapeutic targets ET Van der Westhuizen, ML Halls, CS Samuel, RAD Bathgate, ... Drug discovery today 13 (15-16), 640-651, 2008 | 80 | 2008 |
| Crystal structure of the M5 muscarinic acetylcholine receptor Z Vuckovic, PR Gentry, AE Berizzi, K Hirata, S Varghese, G Thompson, ... Proceedings of the National Academy of Sciences 116 (51), 26001-26007, 2019 | 70 | 2019 |
| Purinergic receptor transactivation by the β2-adrenergic receptor increases intracellular Ca2+ in nonexcitable cells W Stallaert, ET Van Der Westhuizen, AM Schönegge, B Plouffe, M Hogue, ... Molecular pharmacology 91 (5), 533-544, 2017 | 60 | 2017 |
| Inhibin-activin receptor subunit gene expression in ovarian tumors PJ Fuller, ET Zumpe, S Chu, P Mamers, HG Burger The Journal of Clinical Endocrinology & Metabolism 87 (3), 1395-1401, 2002 | 52 | 2002 |
| H2 relaxin is a biased ligand relative to H3 relaxin at the relaxin family peptide receptor 3 (RXFP3) ET van der Westhuizen, A Christopoulos, PM Sexton, JD Wade, ... Molecular pharmacology 77 (5), 759-772, 2010 | 44 | 2010 |
| Responses of GPCR135 to human gene 3 (H3) relaxin in CHO‐K1 cells determined by microphysiometry ET Van der Westhuizen, PM Sexton, RAD Bathgate, RJ Summers Annals of the New York Academy of Sciences 1041 (1), 332-337, 2005 | 42 | 2005 |
| Relaxin receptors-new drug targets for multiple disease states ET Van Der Westhuizen, RJ Summers, ML Halls, RA D Bathgate, ... Current drug targets 8 (1), 91-104, 2007 | 41 | 2007 |
| Fine tuning muscarinic acetylcholine receptor signaling through allostery and bias ET Van der Westhuizen, KHC Choy, C Valant, S McKenzie-Nickson, ... Frontiers in pharmacology 11, 606656, 2021 | 40 | 2021 |
| Relaxin family peptide receptor (RXFP1) coupling to Gαi3 involves the C-terminal Arg752 and localization within membrane raft microdomains ML Halls, ET van der Westhuizen, JD Wade, BA Evans, RAD Bathgate, ... Molecular pharmacology 75 (2), 415-428, 2009 | 33 | 2009 |
| Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response B Benredjem, J Gallion, D Pelletier, P Dallaire, J Charbonneau, D Cawkill, ... Nature communications 10 (1), 4075, 2019 | 32 | 2019 |
Patrick SextonMonash UniversityVerified email at monash.edu
