| Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets YK Tham, BC Bernardo, JYY Ooi, KL Weeks, JR McMullen Archives of toxicology 89, 1401-1438, 2015 | 736 | 2015 |
| Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function BC Bernardo, XM Gao, CE Winbanks, EJH Boey, YK Tham, H Kiriazis, ... Proceedings of the National Academy of Sciences 109 (43), 17615-17620, 2012 | 473 | 2012 |
| Phosphoinositide 3-kinase p110α is a master regulator of exercise-induced cardioprotection and PI3K gene therapy rescues cardiac dysfunction KL Weeks, X Gao, XJ Du, EJH Boey, A Matsumoto, BC Bernardo, ... Circulation: Heart Failure 5 (4), 523-534, 2012 | 138 | 2012 |
| Enhanced phosphoinositide 3-kinase (p110α) activity prevents diabetes-induced cardiomyopathy and superoxide generation in a mouse model of diabetes RH Ritchie, JE Love, K Huynh, BC Bernardo, DC Henstridge, H Kiriazis, ... Diabetologia 55, 3369-3381, 2012 | 99 | 2012 |
| The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice G Sapra, YK Tham, N Cemerlang, A Matsumoto, H Kiriazis, BC Bernardo, ... Nature communications 5 (1), 5705, 2014 | 97 | 2014 |
| Silencing of miR-34a attenuates cardiac dysfunction in a setting of moderate, but not severe, hypertrophic cardiomyopathy BC Bernardo, XM Gao, YK Tham, H Kiriazis, CE Winbanks, JYY Ooi, ... PloS one 9 (2), e90337, 2014 | 83 | 2014 |
| Therapeutic silencing of miR‐652 restores heart function and attenuates adverse remodeling in a setting of established pathological hypertrophy BC Bernardo, SS Nguyen, CE Winbanks, XM Gao, EJH Boey, YK Tham, ... The FASEB Journal 28 (12), 5097-5110, 2014 | 80 | 2014 |
| Inhibition of miR-154 protects against cardiac dysfunction and fibrosis in a mouse model of pressure overload BC Bernardo, SS Nguyen, XM Gao, YK Tham, JYY Ooi, NL Patterson, ... Scientific reports 6 (1), 22442, 2016 | 52 | 2016 |
| Sex differences in response to miRNA‐34a therapy in mouse models of cardiac disease: identification of sex‐, disease‐and treatment‐regulated miRNAs BC Bernardo, JYY Ooi, A Matsumoto, YK Tham, S Singla, H Kiriazis, ... The Journal of physiology 594 (20), 5959-5974, 2016 | 48 | 2016 |
| Lipidomic profiles of the heart and circulation in response to exercise versus cardiac pathology: a resource of potential biomarkers and drug targets YK Tham, BC Bernardo, K Huynh, JYY Ooi, XM Gao, H Kiriazis, C Giles, ... Cell reports 24 (10), 2757-2772, 2018 | 47 | 2018 |
| Distinct lipidomic profiles in models of physiological and pathological cardiac remodeling, and potential therapeutic strategies YK Tham, K Huynh, NA Mellett, DC Henstridge, H Kiriazis, JYY Ooi, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2018 | 25 | 2018 |
| Gene delivery of medium chain acyl-coenzyme A dehydrogenase induces physiological cardiac hypertrophy and protects against pathological remodelling BC Bernardo, KL Weeks, T Pongsukwechkul, X Gao, H Kiriazis, ... Clinical Science 132 (3), 381-397, 2018 | 23 | 2018 |
| FoxO1 is required for physiological cardiac hypertrophy induced by exercise but not by constitutively active PI3K KL Weeks, YK Tham, SG Yildiz, Y Alexander, DG Donner, H Kiriazis, ... American Journal of Physiology-Heart and Circulatory Physiology 320 (4 …, 2021 | 20 | 2021 |
| Novel lipid species for detecting and predicting atrial fibrillation in patients with type 2 diabetes YK Tham, KS Jayawardana, ZH Alshehry, C Giles, K Huynh, AAT Smith, ... Diabetes 70 (1), 255-261, 2021 | 12 | 2021 |
| Estrogen receptor alpha deficiency in cardiomyocytes reprograms the heart-derived extracellular vesicle proteome and induces obesity in female mice YK Tham, BC Bernardo, B Claridge, GS Yildiz, LML Woon, S Bond, ... Nature Cardiovascular Research 2 (3), 268-289, 2023 | 6 | 2023 |
| PI3K (p110α) is a master regulator of exercise-induced cardioprotection and PI3K gene therapy rescues cardiac dysfunction USA York, JR McMullen | 3 | 2012 |
| The therapeutic potential of microRNA-652 for the treatment of heart failure B Bernardo, X Gao, Y Tham, R Lin, H Kiriazis, X Du, J McMullen Heart, Lung and Circulation 22, S60, 2013 | 1 | 2013 |
| Cardiac-targeted Delivery of a Novel Inhibitor of Mitochondrial Fission Protein Drp1 (Dynamin-related Protein) for Cardioprotection J Lees, D Donner, D Rudd, X Lai, T Lin, A Rosdah, S Crawford, A Kong, ... Heart, Lung and Circulation 32, S408, 2023 | | 2023 |
| Temporal Profiling of Circulating Lipids as Potential Biomarkers in a Mouse Model of Heart Failure and Atrial Fibrillation Y Tham, T Belkin, A Matsumoto, J Luo, N Mellett, J McMullen Heart, Lung and Circulation 32, S417-S418, 2023 | | 2023 |
| Alkylglycerol Supplementation Remodels the Cardiac Lipidome and Attenuates Pathological Features in a Mouse Model of Dilated Cardiomyopathy T Belkin, N Mellet, S Yildiz, E Masterman, P Meikle, Y Tham, J McMullen Heart, Lung and Circulation 32, S129-S130, 2023 | | 2023 |
Dr Bianca C. BernardoGroup Leader. Baker Heart and Diabetes Institute, Melbourne, AustraliaVerified email at bakeridi.edu.au
