george fleet
george fleet
Professor of Organic Chemistry
Verified email at - Homepage
Cited by
Cited by
Sugar-mimic glycosidase inhibitors: natural occurrence, biological activity and prospects for therapeutic application
N Asano, RJ Nash, RJ Molyneux, GWJ Fleet
Tetrahedron: Asymmetry 11 (8), 1645-1680, 2000
Polyhydroxylated alkaloids—natural occurrence and therapeutic applications
AA Watson, GWJ Fleet, N Asano, RJ Molyneux, RJ Nash
Phytochemistry 56 (3), 265-295, 2001
Amino-sugar glycosidase inhibitors: versatile tools for glycobiologists
B Winchester, GWJ Fleet
Glycobiology 2 (3), 199-210, 1992
Aminosugar derivatives as potential anti-human immunodeficiency virus agents.
A Karpas, GW Fleet, RA Dwek, S Petursson, SK Namgoong, ...
Proceedings of the National Academy of Sciences 85 (23), 9229-9233, 1988
Inhibition of HIV replication by amino‐sugar derivatives
GWJ Fleet, A Karpas, RA Dwek, LE Fellows, AS Tyms, S Petursson, ...
FEBS letters 237 (1-2), 128-132, 1988
Affinity labelling of antibodies with aryl nitrene as reactive group
GWJ Fleet, RR Porter, JR Knowles
Nature 224 (5218), 511-512, 1969
Potent competitive inhibition of α-galactosidase and α-glucosidase activity by 1, 4-dideoxy-1, 4-iminopentitols: Syntheses of 1, 4-dideoxy-1, 4-imino-d-lyxitol and of both …
GWJ Fleet, SJ Nicholas, PW Smith, SV Evans, LE Fellows, RJ Nash
Tetrahedron letters 26 (26), 3127-3130, 1985
Iminosugars as therapeutic agents: recent advances and promising trends
RJ Nash, A Kato, CY Yu, GWJ Fleet
Future Medicinal Chemistry 3 (12), 1513-1521, 2011
Glycosidase inhibition by plant alkaloids which are structural analogues of monosaccharides
SV Evans, LE Fellows, TKM Shing, GWJ Fleet
Phytochemistry 24 (9), 1953-1955, 1985
New polyhydroxylated pyrrolizidine alkaloids from Muscari armeniacum: structural determination and biological activity
N Asano, H Kuroi, K Ikeda, H Kizu, Y Kameda, A Kato, I Adachi, ...
Tetrahedron: Asymmetry 11 (1), 1-8, 2000
Polyhydroxylated pyrrolidines from sugar lactomes: Synthesis of 1, 4-dideoxy-1, 4-imino-d-glucitol from d-galactonolactone and syntheses of 1, 4-dideoxy-1, 4-imino-d-allitol, 1 …
GWJ Fleet, JC Son
Tetrahedron 44 (9), 2637-2647, 1988
The antibody binding site. Labelling of a specific antibody against the photo-precursor of an aryl nitrene
GWJ Fleet, JR Knowles, RR Porter
Biochemical Journal 128 (3), 499-508, 1972
Isolation from alexa leiopetala and x-ray crystal structure of alexine,(1r, 2r, 3r, 7s, 8s)-3-hydroxymethyl-1, 2, 7-trihydroxypyrrolizidine [(2r, 3r, 4r, 5s, 6s)-2 …
RJ Nash, LE Fellows, JV Dring, GWJ Fleet, AE Derome, TA Hamor, ...
Tetrahedron letters 29 (20), 2487-2490, 1988
Polyhydroxylated pyrrolidine and pyrrolizidine alkaloids from Hyacinthoides non-scripta and Scilla campanulata
A Kato, I Adachi, M Miyauchi, K Ikeda, T Komae, H Kizu, Y Kameda, ...
Carbohydrate research 316 (1-4), 95-103, 1999
Molecular requirements of imino sugars for the selective control of N-linked glycosylation and glycosphingolipid biosynthesis
TD Butters, L Van den Broek, GWJ Fleet, TM Krulle, MR Wormald, ...
Tetrahedron: Asymmetry 11 (1), 113-124, 2000
Potent inhibition of glycogen phosphorylase by a spirohydantoin of glucopyranose: First pyranose analogues of hydantocidin
CJF Bichard, EP Mitchell, MR Wormald, KA Watson, LN Johnson, ...
Tetrahedron letters 36 (12), 2145-2148, 1995
Inhibition of mammalian digestive disaccharidases by polyhydroxy alkaloids
AM Scofield, LE Fellows, RJ Nash, GWJ Fleet
Life sciences 39 (7), 645-650, 1986
10-Helical conformations in oxetane β-amino acid hexamers
TDW Claridge, JM Goodman, A Moreno, D Angus, SF Barker, ...
Tetrahedron Letters 42 (25), 4251-4255, 2001
Glucose analog inhibitors of glycogen phosphorylase: The design of potential drugs for diabetes
JL Martin, K Veluraja, K Ross, LN Johnson, GWJ Fleet, NG Ramsden, ...
Biochemistry 30 (42), 10101-10116, 1991
Design of Inhibitors of Glycogen Phosphorylase: A Study of. alpha.-and. beta.-C-Glucosides and 1-Thio-. beta.-D-glucose Compounds
KA Watson, EP Mitchell, LN Johnson, CJF Bichard, MG Orchard, ...
Biochemistry 33 (19), 5745-5758, 1994
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