| Design, synthesis, and SAR of a novel pyrazinone series with non-nucleoside HIV-1 reverse transcriptase inhibitory activity J Heeres, MR De Jonge, LMH Koymans, FFD Daeyaert, M Vinkers, ... Journal of medicinal chemistry 48 (6), 1910-1918, 2005 | 69 | 2005 |
| Efficient synthesis and docking studies of novel benzothiazole-based pyrimidinesulfonamide scaffolds as new antiviral agents and Hsp90α inhibitors RA Azzam, RR Osman, GH Elgemeie ACS omega 5 (3), 1640-1655, 2020 | 65 | 2020 |
| Synthesis and thermo-mechanical characterization of high performance polyurethane elastomers based on heterocyclic and aromatic diamine chain extenders RA Azzam, SK Mohamed, R Tol, V Everaert, H Reynaers, B Goderis Polymer degradation and stability 92 (7), 1316-1325, 2007 | 59 | 2007 |
| Sulfa drug analogs: new classes of N-sulfonyl aminated azines and their biological and preclinical importance in medicinal chemistry (2000–2018) GH Elgemeie, RA Azzam, RE Elsayed Medicinal Chemistry Research 28, 1099-1131, 2019 | 55 | 2019 |
| Heterocyclic ring extension of estrone: Synthesis and cytotoxicity of fused pyran, pyrimidine and thiazole derivatives RM Mohareb, F Al-Omran, RA Azzam Steroids 84, 46-56, 2014 | 54 | 2014 |
| Design, Synthesis, and Antimicrobial Evaluation of a New Series of N-Sulfonamide 2-Pyridones as Dual Inhibitors of DHPS and DHFR Enzymes RA Azzam, RE Elsayed, GH Elgemeie ACS omega 5 (18), 10401-10414, 2020 | 53 | 2020 |
| Novel Synthesis and Antiviral Evaluation of New Benzothiazole-Bearing N-Sulfonamide 2-Pyridone Derivatives as USP7 Enzyme Inhibitors RA Azzam, HA Elboshi, GH Elgemeie ACS omega 5 (46), 30023-30036, 2020 | 42 | 2020 |
| Molecular-level modeling and experimental investigation into the high performance nature and low hysteresis of thermoplastic polyurethane/multi-walled carbon nanotube … TM Madkour, FM Hagag, W Mamdouh, RA Azzam Polymer 53 (25), 5788-5797, 2012 | 39 | 2012 |
| Tailored-design of electrospun nanofiber cellulose acetate/poly (lactic acid) dressing mats loaded with a newly synthesized sulfonamide analog exhibiting superior wound healing RE Elsayed, TM Madkour, RA Azzam International journal of biological macromolecules 164, 1984-1999, 2020 | 37 | 2020 |
| Multicomponent reactions of acetoacetanilide derivatives with aromatic aldehydes and cyanomethylene reagents to produce 4H-pyran and 1, 4-dihydropyridine derivatives with … RA Azzam, RM Mohareb Chemical and Pharmaceutical Bulletin 63 (12), 1055-1064, 2015 | 36 | 2015 |
| SYNTHETIC POTENTIALITIES OF THIOPHENE SYSTEMS IN HETEROCYCLIC SYNTHESIS: A NOVEL SYNTHESIS OF THIENO[2,3-b]PYRIDINE DERIVATIVES RM Mohareb, HZ Shams, YM Elkholy, RA Azam Phosphorus, Sulfur, and Silicon and the Related Elements 155 (1), 215-233, 1999 | 30 | 1999 |
| Expanding the substitution pattern of 2(1H)-pyrazinones via Suzuki and Heck reactions R Azzam, WM De Borggraeve, F Compernolle, GJ Hoornaert Tetrahedron 61 (16), 3953-3962, 2005 | 29 | 2005 |
| Design and Synthesis of a New Class of Pyridine-Based N-Sulfonamides Exhibiting Antiviral, Antimicrobial, and Enzyme Inhibition Characteristics RA Azzam, RE Elsayed, GH Elgemeie ACS omega 5 (40), 26182-26194, 2020 | 28 | 2020 |
| Synthesis and antimicrobial evaluation of novel N-substituted 4-ethylsulfanyl-2-pyridones and triazolopyridines RA Azzam, GH Elgemeie Medicinal Chemistry Research 28, 62-70, 2019 | 27 | 2019 |
| New routes for the synthesis of 3- and 5-substituted 2(1H)-pyrazinones R Azzam, W De Borggraeve, F Compernolle, GJ Hoornaert Tetrahedron letters 45 (9), 1885-1888, 2004 | 27 | 2004 |
| Synthesis of novel pyrido [2, 1-b] benzothiazole and N-substituted 2-pyridylbenzothiazole derivatives showing remarkable fluorescence and biological activities RA Azzam, GH Elgemeie, RR Osman Journal of Molecular Structure 1201, 127194, 2020 | 26 | 2020 |
| Antimetabolites: A first synthesis of a new class of cytosine thioglycoside analogs G Elgemeie, M Abu-Zaied, R Azzam Nucleosides, Nucleotides and Nucleic Acids 35 (4), 211-222, 2016 | 26 | 2016 |
| Novel nanoporous membranes of bio-based cellulose acetate, poly (lactic acid) and biodegradable polyurethane in-situ impregnated with catalytic cobalt nanoparticles for the … MMH El-Sayed, RE Elsayed, A Attia, HH Farghal, RA Azzam, TM Madkour Carbohydrate Polymer Technologies and Applications 2, 100123, 2021 | 25 | 2021 |
| Crystal structure of N-[6-amino-5-(benzo [d] thiazol-2-yl)-3-cyano-4-methylsulfanyl-2-oxo-1, 2-dihydropyridin-1-yl]-4-methylbenzenesulfonamide dimethylformamide monosolvate RA Azzam, GH Elgemeie, RE Elsayed, PG Jones Acta Crystallographica Section E: Crystallographic Communications 73 (12 …, 2017 | 25 | 2017 |
| Recent advances in synthesis, metal complexes and biological evaluation of 2-aryl, 2-pyridyl and 2-pyrimidylbenzothiazoles as potential chemotherapeutics GH Elgemeie, RA Azzam, RR Osman Inorganica Chimica Acta 502, 119302, 2020 | 22 | 2020 |
