| Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity A Elosegui-Artola, R Oria, Y Chen, A Kosmalska, C Pérez-González, ... Nature cell biology 18 (5), 540-548, 2016 | 810 | 2016 |
| Receptor-mediated cell mechanosensing Y Chen, L Ju, M Rushdi, C Ge, C Zhu Molecular biology of the cell 28 (23), 3134-3155, 2017 | 261 | 2017 |
| An integrin αIIbβ3 intermediate affinity state mediates biomechanical platelet aggregation Y Chen, LA Ju, F Zhou, J Liao, L Xue, QP Su, D Jin, Y Yuan, H Lu, ... Nature materials 18 (7), 760-769, 2019 | 140 | 2019 |
| Dynamic catch of a Thy-1–α5β1+syndecan-4 trimolecular complex VF Fiore, L Ju, Y Chen, C Zhu, TH Barker Nature communications 5 (1), 4886, 2014 | 108 | 2014 |
| Force regulated conformational change of integrin αVβ3 Y Chen, H Lee, H Tong, M Schwartz, C Zhu Matrix biology 60, 70-85, 2017 | 103 | 2017 |
| Apolipoprotein A-IV binds αIIbβ3 integrin and inhibits thrombosis XR Xu, Y Wang, R Adili, L Ju, CM Spring, JW Jin, H Yang, MAD Neves, ... Nature communications 9 (1), 3608, 2018 | 97 | 2018 |
| Cooperative unfolding of distinctive mechanoreceptor domains transduces force into signals L Ju✝, Y Chen✝, L Xue, X Du, C Zhu Elife 5, e15447, 2016 | 96 | 2016 |
| Von Willebrand factor-A1 domain binds platelet glycoprotein Ibα in multiple states with distinctive force-dependent dissociation kinetics L Ju, Y Chen, F Zhou, H Lu, MA Cruz, C Zhu Thrombosis research 136 (3), 606-612, 2015 | 79 | 2015 |
| A lupus-associated Mac-1 variant has defects in integrin allostery and interaction with ligands under force F Rosetti✝, Y Chen✝, M Sen, E Thayer, V Azcutia, JM Herter, ... Cell reports 10 (10), 1655-1664, 2015 | 77 | 2015 |
| The integrin PSI domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy G Zhu, Q Zhang, EC Reddy, N Carrim, Y Chen, XR Xu, M Xu, Y Wang, ... Blood, The Journal of the American Society of Hematology 129 (13), 1840-1854, 2017 | 71 | 2017 |
| Shear-induced integrin signaling in platelet phosphatidylserine exposure, microvesicle release, and coagulation A Pang, Y Cui, Y Chen, N Cheng, MK Delaney, M Gu, A Stojanovic-Terpo, ... Blood, The Journal of the American Society of Hematology 132 (5), 533-543, 2018 | 70 | 2018 |
| Fluorescence biomembrane force probe: concurrent quantitation of receptor-ligand kinetics and binding-induced intracellular signaling on a single cell Y Chen, B Liu, L Ju, J Hong, Q Ji, W Chen, C Zhu Journal of visualized experiments: JoVE, 2015 | 60 | 2015 |
| Cis interaction between sialylated FcγRIIA and the αI-domain of Mac-1 limits antibody-mediated neutrophil recruitment G Saggu, K Okubo, Y Chen, R Vattepu, N Tsuboi, F Rosetti, X Cullere, ... Nature communications 9 (1), 5058, 2018 | 53 | 2018 |
| Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases H Nishi, K Furuhashi, X Cullere, G Saggu, MJ Miller, Y Chen, F Rosetti, ... The Journal of clinical investigation 127 (10), 3810-3826, 2017 | 53 | 2017 |
| Compression force sensing regulates integrin αIIbβ3 adhesive function on diabetic platelets L Ju, JD McFadyen, S Al-Daher, I Alwis, Y Chen, LL Třnnesen, ... Nature communications 9 (1), 1087, 2018 | 52 | 2018 |
| Dual Biomembrane Force Probe enables single-cell mechanical analysis of signal crosstalk between multiple molecular species L Ju, Y Chen, K Li, Z Yuan, B Liu, SP Jackson, C Zhu Scientific reports 7 (1), 14185, 2017 | 47 | 2017 |
| 14-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling Y Chen, ZM Ruggeri, X Du Blood, The Journal of the American Society of Hematology 131 (22), 2436-2448, 2018 | 46 | 2018 |
| Dynamic bonds and their roles in mechanosensing C Zhu, Y Chen, LA Ju Current opinion in chemical biology 53, 88-97, 2019 | 40 | 2019 |
| Force-induced unfolding of leucine-rich repeats of glycoprotein Ibα strengthens ligand interaction L Ju, J Lou, Y Chen, Z Li, C Zhu Biophysical journal 109 (9), 1781-1784, 2015 | 37 | 2015 |
| Biomechanical thrombosis: the dark side of force and dawn of mechano-medicine Y Chen, LA Ju Stroke and vascular neurology 5 (2), 2020 | 32 | 2020 |
Cheng ZhuJ. Erskine Love Jr. Endowed Chair in Engineering and Regents' ProfessorVerified email at bme.gatech.edu
