Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder D Demontis, RK Walters, J Martin, M Mattheisen, TD Als, E Agerbo, ... Nature genetics 51 (1), 63, 2019 | 870 | 2019 |
Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism NN Parikshak, R Luo, A Zhang, H Won, JK Lowe, V Chandran, S Horvath, ... Cell 155 (5), 1008-1021, 2013 | 755 | 2013 |
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection AF Pardiņas, P Holmans, AJ Pocklington, V Escott-Price, S Ripke, ... Nature genetics 50 (3), 381-389, 2018 | 690 | 2018 |
Identification of common genetic risk variants for autism spectrum disorder J Grove, S Ripke, TD Als, M Mattheisen, RK Walters, H Won, J Pallesen, ... Nature genetics 51 (3), 431-444, 2019 | 636* | 2019 |
Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function H Won, HR Lee, HY Gee, W Mah, JI Kim, J Lee, S Ha, C Chung, ES Jung, ... Nature 486 (7402), 261-265, 2012 | 527 | 2012 |
Advancing the understanding of autism disease mechanisms through genetics L de la Torre-Ubieta, H Won, JL Stein, DH Geschwind Nature medicine 22 (4), 345-361, 2016 | 497 | 2016 |
Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder MJ Gandal, P Zhang, E Hadjimichael, RL Walker, C Chen, S Liu, H Won, ... Science 362 (6420), 2018 | 352 | 2018 |
Chromosome conformation elucidates regulatory relationships in developing human brain H Won, L de La Torre-Ubieta, JL Stein, NN Parikshak, J Huang, ... Nature 538 (7626), 523-527, 2016 | 342 | 2016 |
Comprehensive functional genomic resource and integrative model for the human brain D Wang, S Liu, J Warrell, H Won, X Shi, FCP Navarro, D Clarke, M Gu, ... Science 362 (6420), 2018 | 315 | 2018 |
Integrative functional genomic analysis of human brain development and neuropsychiatric risks M Li, G Santpere, YI Kawasawa, OV Evgrafov, FO Gulden, S Pochareddy, ... Science 362 (6420), 2018 | 226 | 2018 |
Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights A Gusev, N Mancuso, H Won, M Kousi, HK Finucane, Y Reshef, L Song, ... Nature genetics 50 (4), 538-548, 2018 | 190 | 2018 |
The psychencode project S Akbarian, C Liu, JA Knowles, FM Vaccarino, PJ Farnham, GE Crawford, ... Nature neuroscience 18 (12), 1707-1712, 2015 | 185 | 2015 |
Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses H Won, W Mah, E Kim Frontiers in molecular neuroscience 6, 19, 2013 | 170 | 2013 |
The road to precision psychiatry: translating genetics into disease mechanisms MJ Gandal, V Leppa, H Won, NN Parikshak, DH Geschwind Nature neuroscience 19 (11), 1397-1407, 2016 | 169 | 2016 |
The dynamic landscape of open chromatin during human cortical neurogenesis L de la Torre-Ubieta, JL Stein, H Won, CK Opland, D Liang, D Lu, ... Cell 172 (1-2), 289-304. e18, 2018 | 158 | 2018 |
De novo mutations in regulatory elements in neurodevelopmental disorders PJ Short, JF McRae, G Gallone, A Sifrim, H Won, DH Geschwind, ... Nature 555 (7698), 611-616, 2018 | 141 | 2018 |
Enhanced NMDA receptor-mediated synaptic transmission, enhanced long-term potentiation, and impaired learning and memory in mice lacking IRSp53 MH Kim, J Choi, J Yang, W Chung, JH Kim, SK Paik, K Kim, S Han, H Won, ... Journal of Neuroscience 29 (5), 1586-1595, 2009 | 124 | 2009 |
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ... Cell 179 (7), 1469-1482. e11, 2019 | 119 | 2019 |
GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice H Won, W Mah, E Kim, JW Kim, EK Hahm, MH Kim, S Cho, J Kim, H Jang, ... Nature medicine 17 (5), 566-572, 2011 | 119 | 2011 |
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk P Rajarajan, T Borrman, W Liao, N Schrode, E Flaherty, C Casiņo, ... Science 362 (6420), 2018 | 91 | 2018 |