Rui WU
Rui WU
Weill Cornell Medicine
Verified email at med.cornell.edu
Title
Cited by
Cited by
Year
Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT
R Edayathumangalam, R Wu, R Garcia, Y Wang, W Wang, CA Kreinbring, ...
Proceedings of the National Academy of Sciences 110 (44), 17820-17825, 2013
612013
The active site sulfenic acid ligand in nitrile hydratases can function as a nucleophile
S Martinez, R Wu, R Sanishvili, D Liu, R Holz
Journal of the American Chemical Society 136 (4), 1186-1189, 2014
492014
Rational Design of a Transition State Analogue with Picomolar Affinity for Pseudomonas aeruginosa PvdQ, a Siderophore Biosynthetic Enzyme
KD Clevenger, R Wu, JAV Er, D Liu, W Fast
ACS chemical biology 8 (10), 2192-2200, 2013
362013
Design and Mechanism of Tetrahydrothiophene-Based γ-Aminobutyric Acid Aminotransferase Inactivators
HV Le, DD Hawker, R Wu, E Doud, J Widom, R Sanishvili, D Liu, ...
Journal of the American Chemical Society 137 (13), 4525-4533, 2015
232015
Mechanism of Inactivation of γ-Aminobutyric Acid Aminotransferase by (1S,3S)-3-Amino-4-difluoromethylene-1-cyclopentanoic Acid (CPP-115)
H Lee, EH Doud, R Wu, R Sanishvili, JI Juncosa, D Liu, NL Kelleher, ...
Journal of the American Chemical Society 137 (7), 2628-2640, 2015
222015
PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation
R Wu, R Sanishvili, BR Belitsky, JI Juncosa, HV Le, HJS Lehrer, M Farley, ...
Proceedings of the National Academy of Sciences 114 (15), 3891-3896, 2017
212017
The crystal structure of Nitrosomonas europaea sucrose synthase reveals critical conformational changes and insights into sucrose metabolism in prokaryotes
R Wu, MDA Diez, CM Figueroa, M Machtey, AA Iglesias, MA Ballicora, ...
Journal of bacteriology 197 (17), 2734-2746, 2015
202015
SIMBAD: a sequence-independent molecular-replacement pipeline
AJ Simpkin, F Simkovic, JMH Thomas, M Savko, A Lebedev, V Uski, ...
Acta Crystallographica Section D: Structural Biology 74 (7), 595-605, 2018
172018
Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid
H Lee, HV Le, R Wu, E Doud, R Sanishvili, JF Kellie, PD Compton, ...
ACS chemical biology 10 (9), 2087-2098, 2015
112015
n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ
KD Clevenger, R Wu, D Liu, W Fast
Biochemistry 53 (42), 6679-6686, 2014
112014
Analyzing the catalytic role of active site residues in the Fe-type nitrile hydratase from Comamonas testosteroni Ni1
S Martinez, R Wu, K Krzywda, V Opalka, H Chan, D Liu, RC Holz
JBIC Journal of Biological Inorganic Chemistry 20 (5), 885-894, 2015
62015
Molecular mechanism and ligand design of a PLP/GABA-dependent bacterial transcription regulator GabR
E Cybulla, R Wu, C Reidl, D Gawron, D Becker, D Liu
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249, 2015
2015
Structure and Molecular Mechanism of a PLP/GABA Dependent Transcription Regulator GabR
R Wu
2015
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