Anne Brunet
Anne Brunet
Professor of Genetics, Stanford University
Verified email at - Homepage
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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
A Brunet, A Bonni, MJ Zigmond, MZ Lin, P Juo, LS Hu, MJ Anderson, ...
cell 96 (6), 857-868, 1999
Cellular survival: a play in three Akts
SR Datta, A Brunet, ME Greenberg
Genes & development 13 (22), 2905-2927, 1999
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
A Brunet, LB Sweeney, JF Sturgill, KF Chua, PL Greer, Y Lin, H Tran, ...
science 303 (5666), 2011-2015, 2004
Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and-independent mechanisms
A Bonni, A Brunet, AE West, SR Datta, MA Takasu, ME Greenberg
Science 286 (5443), 1358-1362, 1999
Geroscience: linking aging to chronic disease
BK Kennedy, SL Berger, A Brunet, J Campisi, AM Cuervo, ES Epel, ...
Cell 159 (4), 709-713, 2014
Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway
JN Lavoie, G L'Allemain, A Brunet, R Müller, J Pouysségur
Journal of Biological Chemistry 271 (34), 20608-20616, 1996
FOXO transcription factors at the interface between longevity and tumor suppression
EL Greer, A Brunet
Oncogene 24 (50), 7410-7425, 2005
Transcription-dependent and-independent control of neuronal survival by the PI3K–Akt signaling pathway
A Brunet, SR Datta, ME Greenberg
Current opinion in neurobiology 11 (3), 297-305, 2001
The foxo code
DR Calnan, A Brunet
Oncogene 27 (16), 2276-2288, 2008
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
A Brunet, J Park, H Tran, LS Hu, BA Hemmings, ME Greenberg
Molecular and cellular biology, 2001
DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein
H Tran, A Brunet, JM Grenier, SR Datta, AJ Fornace Jr, PS DiStefano, ...
Science 296 (5567), 530-534, 2002
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor
EL Greer, PR Oskoui, MR Banko, JM Maniar, MP Gygi, SP Gygi, A Brunet
Journal of Biological Chemistry 282 (41), 30107-30119, 2007
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans
EL Greer, D Dowlatshahi, MR Banko, J Villen, K Hoang, D Blanchard, ...
Current biology 17 (19), 1646-1656, 2007
Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts
P Lenormand, C Sardet, G Pages, G L'Allemain, A Brunet, J Pouysségur
The Journal of cell biology 122 (5), 1079-1088, 1993
AMPK: an energy-sensing pathway with multiple inputs and outputs
DG Hardie, BE Schaffer, A Brunet
Trends in cell biology 26 (3), 190-201, 2016
Nuclear translocation of p42/p44 mitogen‐activated protein kinase is required for growth factor‐induced gene expression and cell cycle entry
A Brunet, D Roux, P Lenormand, S Dowd, S Keyse, J Pouysségur
The EMBO journal, 1999
14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport
A Brunet, F Kanai, J Stehn, J Xu, D Sarbassova, JV Frangioni, SN Dalal, ...
The Journal of cell biology 156 (5), 817-828, 2002
Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans
EL Greer, TJ Maures, D Ucar, AG Hauswirth, E Mancini, JP Lim, ...
Nature 479 (7373), 365-371, 2011
FoxO transcription factors in the maintenance of cellular homeostasis during aging
DAM Salih, A Brunet
Current opinion in cell biology 20 (2), 126-136, 2008
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans
EL Greer, A Brunet
Aging cell 8 (2), 113-127, 2009
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