| Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease JA Duce, A Tsatsanis, MA Cater, SA James, E Robb, K Wikhe, SL Leong, ... Cell 142 (6), 857-867, 2010 | 815 | 2010 |
| Relating cytotoxicity, zinc ions, and reactive oxygen in ZnO nanoparticle–exposed human immune cells C Shen, SA James, MD de Jonge, TW Turney, PFA Wright, BN Feltis Toxicological Sciences 136 (1), 120-130, 2013 | 254 | 2013 |
| Maia X-ray fluorescence imaging: Capturing detail in complex natural samples CG Ryan, DP Siddons, R Kirkham, ZY Li, MD De Jonge, DJ Paterson, ... Journal of Physics: Conference Series 499 (1), 012002, 2014 | 219 | 2014 |
| Elevated labile Cu is associated with oxidative pathology in Alzheimer disease SA James, I Volitakis, PA Adlard, JA Duce, CL Masters, RA Cherny, ... Free Radical Biology and Medicine 52 (2), 298-302, 2012 | 192 | 2012 |
| Iron, copper, and zinc concentration in Aβ plaques in the APP/PS1 mouse model of Alzheimer’s disease correlates with metal levels in the surrounding neuropil SA James, QI Churches, MD de Jonge, IE Birchall, V Streltsov, G McColl, ... ACS chemical neuroscience 8 (3), 629-637, 2017 | 125 | 2017 |
| Quantification of ZnO nanoparticle uptake, distribution, and dissolution within individual human macrophages SA James, BN Feltis, MD de Jonge, M Sridhar, JA Kimpton, M Altissimo, ... ACS nano 7 (12), 10621-10635, 2013 | 119 | 2013 |
| Changes in ferrous iron and glutathione promote ferroptosis and frailty in aging Caenorhabditis elegans NL Jenkins, SA James, A Salim, F Sumardy, TP Speed, M Conrad, ... Elife 9, e56580, 2020 | 109 | 2020 |
| Direct in vivo imaging of ferrous iron dyshomeostasis in ageing Caenorhabditis elegans SA James, BR Roberts, DJ Hare, MD de Jonge, IE Birchall, NL Jenkins, ... Chemical Science, 2015 | 98 | 2015 |
| Laterally resolved speciation of arsenic in roots of wheat and rice using fluorescence‐XANES imaging PM Kopittke, MD de Jonge, P Wang, BA McKenna, E Lombi, DJ Paterson, ... New Phytologist 201 (4), 1251-1262, 2014 | 79 | 2014 |
| Evidence from Dura Europos for the origins of Late Roman helmets S James Syria 63 (Fasc. 1/2), 107-134, 1986 | 77 | 1986 |
| Significant accumulation of polymyxin in single renal tubular cells: a medicinal chemistry and triple correlative microscopy approach MAK Azad, KD Roberts, HH Yu, B Liu, AV Schofield, SA James, ... Analytical chemistry 87 (3), 1590-1595, 2015 | 69 | 2015 |
| Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist B Cao, Z Zhang, J Grassinger, B Williams, CK Heazlewood, QI Churches, ... Nature communications 7 (1), 11007, 2016 | 63 | 2016 |
| Metal chaperones prevent zinc-mediated cognitive decline PA Adlard, J Parncutt, V Lal, S James, D Hare, P Doble, DI Finkelstein, ... Neurobiology of disease 81, 196-202, 2015 | 61 | 2015 |
| Caenorhabditis elegans maintains highly compartmentalized cellular distribution of metals and steep concentration gradients of manganese G McColl, SA James, S Mayo, DL Howard, CG Ryan, R Kirkham, ... PloS one 7 (2), e32685, 2012 | 60 | 2012 |
| Quantitative comparison of preparation methodologies for x-ray fluorescence microscopy of brain tissue SA James, DE Myers, MD de Jonge, S Vogt, CG Ryan, BA Sexton, ... Analytical and bioanalytical chemistry 401, 853-864, 2011 | 60 | 2011 |
| A domain level interaction network of amyloid precursor protein and Aβ of Alzheimer's disease VM Perreau, S Orchard, PA Adlard, SA Bellingham, R Cappai, ... Proteomics 10 (12), 2377-2395, 2010 | 57 | 2010 |
| The challenges of using a copper fluorescent sensor (CS1) to track intracellular distributions of copper in neuronal and glial cells KA Price, JL Hickey, Z Xiao, AG Wedd, SA James, JR Liddell, PJ Crouch, ... Chemical Science 3 (9), 2748-2759, 2012 | 56 | 2012 |
| Direct in vivo imaging of essential bioinorganics in Caenorhabditis elegans SA James, MD de Jonge, DL Howard, AI Bush, D Paterson, G McColl Metallomics 5 (6), 627-635, 2013 | 52 | 2013 |
| Structural insights into the interaction of platinum-based inhibitors with the Alzheimer's disease amyloid-β peptide VA Streltsov, VC Epa, SA James, QI Churches, JM Caine, VB Kenche, ... Chemical communications 49 (97), 11364-11366, 2013 | 52 | 2013 |
| φXANES: In vivo imaging of metal-protein coordination environments SA James, DJ Hare, NL Jenkins, MD de Jonge, AI Bush, G McColl Scientific Reports 6 (1), 20350, 2016 | 50 | 2016 |
Ashley BushMassachusetts General Hospital, Florey Institute of Neuroscience & Mental HealthVerified email at helix.mgh.harvard.edu
