Fructose-1, 6-bisphosphate couples glycolytic flux to activation of Ras K Peeters, F Van Leemputte, B Fischer, BM Bonini, H Quezada, ... Nature communications 8 (1), 922, 2017 | 200 | 2017 |
Microbial-based therapy of cancer: current progress and future prospects N Bernardes, R Seruca, AM Chakrabarty, AM Fialho Bioengineered bugs 1 (3), 178-190, 2010 | 107 | 2010 |
Scalable production of human mesenchymal stromal cell-derived extracellular vesicles under serum-/xeno-free conditions in a microcarrier-based bioreactor culture system M de Almeida Fuzeta, N Bernardes, FD Oliveira, AC Costa, ... Frontiers in Cell and Developmental Biology 8, 553444, 2020 | 104 | 2020 |
Perturbing the dynamics and organization of cell membrane components: a new paradigm for cancer-targeted therapies N Bernardes, A M. Fialho International journal of molecular sciences 19 (12), 3871, 2018 | 90 | 2018 |
Engineering of bacterial strains and their products for cancer therapy N Bernardes, AM Chakrabarty, AM Fialho Applied microbiology and biotechnology 97, 5189-5199, 2013 | 87 | 2013 |
The antibacterial properties of docosahexaenoic omega-3 fatty acid against the cystic fibrosis multiresistant pathogen Burkholderia cenocepacia D Mil-Homens, N Bernardes, AM Fialho FEMS microbiology letters 328 (1), 61-69, 2012 | 81 | 2012 |
The bacterial protein azurin impairs invasion and FAK/Src signaling in P-cadherin-overexpressing breast cancer cell models N Bernardes, AS Ribeiro, S Abreu, B Mota, RG Matos, CM Arraiano, ... PloS one 8 (7), e69023, 2013 | 55 | 2013 |
Bacterial proteins and peptides in cancer therapy: today and tomorrow AM Chakrabarty, N Bernardes, AM Fialho Bioengineered 5 (4), 234-242, 2014 | 54 | 2014 |
Modulation of membrane properties of lung cancer cells by azurin enhances the sensitivity to EGFR-targeted therapy and decreased β1 integrin-mediated adhesion N Bernardes, S Abreu, FA Carvalho, F Fernandes, NC Santos, AM Fialho Cell Cycle 15 (11), 1415-1424, 2016 | 47 | 2016 |
p28-functionalized PLGA nanoparticles loaded with gefitinib reduce tumor burden and metastases formation on lung cancer AR Garizo, F Castro, C Martins, A Almeida, TP Dias, F Fernardes, ... Journal of Controlled Release 337, 329-342, 2021 | 39 | 2021 |
High-throughput molecular profiling of a P-cadherin overexpressing breast cancer model reveals new targets for the anti-cancer bacterial protein azurin N Bernardes, AS Ribeiro, S Abreu, AF Vieira, L Carreto, M Santos, ... The international journal of biochemistry & cell biology 50, 1-9, 2014 | 38 | 2014 |
Exploring the anticancer potential of the bacterial protein azurin AM Fialho, N Bernardes, AM Chakrabarty AIMS Microbiology 2 (3), 292-303, 2016 | 30 | 2016 |
Azurin interaction with the lipid raft components ganglioside GM-1 and caveolin-1 increases membrane fluidity and sensitivity to anti-cancer drugs N Bernardes, AR Garizo, SN Pinto, B Caniço, C Perdigão, F Fernandes, ... Cell Cycle 17 (13), 1649-1666, 2018 | 27 | 2018 |
Recent patents on live bacteria and their products as potential anticancer agents. AM Fialho, N Bernardes, AM Chakrabarty Recent Patents on Anti-Cancer Drug Discovery 7 (1), 31-55, 2012 | 22 | 2012 |
Conditioned medium from azurin-expressing human mesenchymal stromal cells demonstrates antitumor activity against breast and lung cancer cell lines M Silva, GA Monteiro, AM Fialho, N Bernardes, CUL Da Silva Frontiers in Cell and Developmental Biology 8, 471, 2020 | 14 | 2020 |
The azurin-derived peptide ct-p19lc exhibits membrane-active properties and induces cancer cell death AR Garizo, LF Coelho, S Pinto, TP Dias, F Fernandes, N Bernardes, ... Biomedicines 9 (9), 1194, 2021 | 9 | 2021 |
Bacterial protein azurin as a new candidate drug to treat untreatable breast cancers N Bernardes, AS Ribeiro, R Seruca, J Paredes, AM Fialho 1st Portuguese Biomedical Engineering Meeting, 1-4, 2011 | 8 | 2011 |
From promise to reality: Bioengineering strategies to enhance the therapeutic potential of extracellular vesicles M de Almeida Fuzeta, PP Gonçalves, A Fernandes-Platzgummer, ... Bioengineering 9 (11), 675, 2022 | 7 | 2022 |
Scalable production of human mesenchymal stromal cell-derived extracellular vesicles under serum-/xeno-free conditions in a microcarrier-based bioreactor culture system. Front … M de Almeida Fuzeta, N Bernardes, FD Oliveira, AC Costa, ... | 7 | 2020 |
Burkholderia cenocepacia BCAM2418‐induced antibody inhibits bacterial adhesion, confers protection to infection and enables identification of host glycans as … AI Pimenta, M Kilcoyne, N Bernardes, D Mil‐Homens, L Joshi, AM Fialho Cellular Microbiology 23 (8), e13340, 2021 | 6 | 2021 |