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Sarah Buchan
Sarah Buchan
Verified email at bournemouth.ac.uk
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Year
The immunobiology of CD27 and OX40 and their potential as targets for cancer immunotherapy
SL Buchan, A Rogel, A Al-Shamkhani
Blood, The Journal of the American Society of Hematology 131 (1), 39-48, 2018
2252018
DNA vaccines to attack cancer
FK Stevenson, CH Ottensmeier, P Johnson, D Zhu, SL Buchan, ...
Proceedings of the National Academy of Sciences 101 (suppl_2), 14646-14652, 2004
1772004
Electroporation as a “prime/boost” strategy for naked DNA vaccination against a tumor antigen
S Buchan, E Grønevik, I Mathiesen, CA King, FK Stevenson, J Rice
The Journal of Immunology 174 (10), 6292-6298, 2005
1362005
Antibodies to costimulatory receptor 4-1BB enhance anti-tumor immunity via T regulatory cell depletion and promotion of CD8 T cell effector function
SL Buchan, L Dou, M Remer, SG Booth, SN Dunn, C Lai, M Semmrich, ...
Immunity 49 (5), 958-970. e7, 2018
1332018
DNA fusion vaccine designed to induce cytotoxic T cell responses against defined peptide motifs: implications for cancer vaccines
J Rice, T Elliott, S Buchan, FK Stevenson
The Journal of Immunology 167 (3), 1558-1565, 2001
1242001
Critical components of a DNA fusion vaccine able to induce protective cytotoxic T cells against a single epitope of a tumor antigen
J Rice, S Buchan, FK Stevenson
The Journal of Immunology 169 (7), 3908-3913, 2002
1122002
PD-1 Blockade and CD27 Stimulation Activate Distinct Transcriptional Programs That Synergize for CD8+ T-Cell–Driven Antitumor Immunity
SL Buchan, M Fallatah, SM Thirdborough, VY Taraban, A Rogel, ...
Clinical cancer research 24 (10), 2383-2394, 2018
1022018
Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia
VY Taraban, TJ Slebioda, JE Willoughby, SL Buchan, S James, B Sheth, ...
Mucosal immunology 4 (2), 186-196, 2011
1012011
OX40-and CD27-mediated costimulation synergizes with anti–PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence
SL Buchan, T Manzo, B Flutter, A Rogel, N Edwards, L Zhang, ...
The Journal of Immunology 194 (1), 125-133, 2015
922015
Differential impact of CD27 and 4-1BB costimulation on effector and memory CD8 T cell generation following peptide immunization
JE Willoughby, JP Kerr, A Rogel, VY Taraban, SL Buchan, PWM Johnson, ...
The Journal of Immunology 193 (1), 244-251, 2014
722014
DNA vaccination induces WT1-specific T-cell responses with potential clinical relevance
C Chaise, SL Buchan, J Rice, J Marquet, H Rouard, M Kuentz, GE Vittes, ...
Blood, The Journal of the American Society of Hematology 112 (7), 2956-2964, 2008
712008
Triggering of TNFRSF25 promotes CD8+ T‐cell responses and anti‐tumor immunity
TJ Slebioda, TF Rowley, JR Ferdinand, JE Willoughby, SL Buchan, ...
European Journal of Immunology 41 (9), 2606-2611, 2011
662011
The impact of viral mutations on recognition by SARS-CoV-2 specific T cells
TI de Silva, G Liu, BB Lindsey, D Dong, SC Moore, NS Hsu, D Shah, ...
Iscience 24 (11), 2021
622021
Common patterns of B cell perturbation and expanded V4-34 immunoglobulin gene usage in autoimmunity and infection
C Ian Mockridge, A Rahman, S Buchan, T Hamblin, DA Isenberg, ...
Autoimmunity 37 (1), 9-15, 2004
532004
Disturbances in peripheral blood B cell subpopulations in autoimmune patients
KN Potter, CI Mockridge, A Rahman, S Buchan, T Hamblin, B Davidson, ...
Lupus 11 (12), 872-877, 2002
492002
Akt signaling is critical for memory CD8+ T-cell development and tumor immune surveillance
A Rogel, JE Willoughby, SL Buchan, HJ Leonard, SM Thirdborough, ...
Proceedings of the National Academy of Sciences 114 (7), E1178-E1187, 2017
462017
Death receptor 3 is essential for generating optimal protective CD41 T‐cell immunity against Salmonella
SL Buchan, VY Taraban, TJ Slebioda, S James, AF Cunningham, ...
European journal of immunology 42 (3), 580-588, 2012
432012
CD27 costimulation contributes substantially to the expansion of functional memory CD8+ T cells after peptide immunization
VY Taraban, TF Rowley, JP Kerr, JE Willoughby, PMW Johnson, ...
European journal of immunology 43 (12), 3314-3323, 2013
392013
DNA fusion vaccines induce targeted epitope-specific CTLs against minor histocompatibility antigens from a normal or tolerized repertoire
J Rice, S Buchan, H Dewchand, E Simpson, FK Stevenson
The Journal of Immunology 173 (7), 4492-4499, 2004
382004
Distinct motifs in the intracellular domain of human CD30 differentially activate canonical and alternative transcription factor NF-κB signaling
SL Buchan, A Al-Shamkhani
Public Library of Science 7 (9), e45244, 2012
362012
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