Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin … V Martínez-Cisuelo, J Gómez, I García-Junceda, A Naudí, R Cabré, ... Experimental gerontology 83, 130-138, 2016 | 126 | 2016 |
Human aging is a metabolome-related matter of gender M Jové, I Maté, A Naudí, N Mota-Martorell, M Portero-Otín, M De la Fuente, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2016 | 86 | 2016 |
The advanced lipoxidation end-product malondialdehyde-lysine in aging and longevity M Jové, N Mota-Martorell, I Pradas, M Martín-Gari, V Ayala, R Pamplona Antioxidants 9 (11), 1132, 2020 | 67 | 2020 |
Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous … A Naudí, R Cabré, M Dominguez-Gonzalez, V Ayala, M Jové, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2017 | 60 | 2017 |
Cysteine dietary supplementation reverses the decrease in mitochondrial ROS production at complex I induced by methionine restriction A Gomez, J Gomez, ML Torres, A Naudi, N Mota-Martorell, R Pamplona, ... Journal of bioenergetics and biomembranes 47, 199-208, 2015 | 54 | 2015 |
Sixty years old is the breakpoint of human frontal cortex aging R Cabré, A Naudí, M Dominguez-Gonzalez, V Ayala, M Jové, ... Free Radical Biology and Medicine 103, 14-22, 2017 | 38 | 2017 |
Lipid profile in human frontal cortex is sustained throughout healthy adult life span to decay at advanced ages R Cabré, A Naudí, M Dominguez-Gonzalez, M Jové, V Ayala, ... The Journals of Gerontology: Series A 73 (6), 703-710, 2018 | 27 | 2018 |
Specific metabolomics adaptations define a differential regional vulnerability in the adult human cerebral cortex R Cabré, M Jové, A Naudí, V Ayala, G Piñol-Ripoll, MP Gil-Villar, ... Frontiers in Molecular Neuroscience 9, 138, 2016 | 26 | 2016 |
The lipidome fingerprint of longevity M Jové, N Mota-Martorell, I Pradas, JD Galo-Licona, M Martín-Gari, È Obis, ... Molecules 25 (18), 4343, 2020 | 25 | 2020 |
Low abundance of NDUFV2 and NDUFS4 subunits of the hydrophilic complex I domain and VDAC1 predicts mammalian longevity N Mota-Martorell, M Jove, I Pradas, I Sanchez, J Gómez, A Naudi, G Barja, ... Redox Biology 34, 101539, 2020 | 25 | 2020 |
Methionine transsulfuration pathway is upregulated in long-lived humans N Mota-Martorell, M Jové, C Borrás, R Berdún, E Obis, J Sol, R Cabre, ... Free Radical Biology and Medicine 162, 38-52, 2021 | 24 | 2021 |
The causal role of lipoxidative damage in mitochondrial bioenergetic dysfunction linked to Alzheimer’s disease pathology M Jové, N Mota-Martorell, P Torres, V Ayala, M Portero-Otin, I Ferrer, ... Life 11 (5), 388, 2021 | 21 | 2021 |
Gene expression and regulatory factors of the mechanistic target of rapamycin (mTOR) complex 1 predict mammalian longevity N Mota-Martorell, M Jove, I Pradas, R Berdún, I Sanchez, A Naudi, E Gari, ... Geroscience 42, 1157-1173, 2020 | 18 | 2020 |
Effects of aging and methionine restriction on rat kidney metabolome I Pradas, M Jové, R Cabré, V Ayala, N Mota-Martorell, R Pamplona Metabolites 9 (11), 280, 2019 | 18 | 2019 |
Selective brain regional changes in lipid profile with human aging N Mota-Martorell, P Andrés-Benito, M Martín-Gari, JD Galo-Licona, J Sol, ... GeroScience 44 (2), 763-783, 2022 | 17 | 2022 |
Age-related changes in lipidome of rat frontal cortex and cerebellum are partially reversed by methionine restriction applied in old age M Jové, R Cabré, N Mota-Martorell, M Martin-Garí, È Obis, P Ramos, ... International Journal of Molecular Sciences 22 (22), 12517, 2021 | 15 | 2021 |
Alterations in one-carbon metabolism in celiac disease R Martín-Masot, N Mota-Martorell, M Jové, J Maldonado, R Pamplona, ... Nutrients 12 (12), 3723, 2020 | 15 | 2020 |
Succination of protein thiols in human brain aging M Jové, I Pradas, N Mota-Martorell, R Cabré, V Ayala, I Ferrer, ... Frontiers in Aging Neuroscience 12, 52, 2020 | 15 | 2020 |
Is the NDUFV2 subunit of the hydrophilic complex I domain a key determinant of animal longevity? R Pamplona, M Jové, N Mota‐Martorell, G Barja The FEBS Journal 288 (23), 6652-6673, 2021 | 13 | 2021 |
Plasma methionine metabolic profile is associated with longevity in mammals N Mota-Martorell, M Jové, R Berdún, R Pamplona Communications biology 4 (1), 725, 2021 | 13 | 2021 |