| The FAIR Guiding Principles for scientific data management and stewardship MD Wilkinson, M Dumontier, IJJ Aalbersberg, G Appleton, M Axton, ... Scientific data 3, 2016 | 2408 | 2016 |
| Structure of the PPARα and-γ ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family P Cronet, JFW Petersen, R Folmer, N Blomberg, K Sjöblom, U Karlsson, ... Structure 9 (8), 699-706, 2001 | 332 | 2001 |
| Open PHACTS: semantic interoperability for drug discovery AJ Williams, L Harland, P Groth, S Pettifer, C Chichester, EL Willighagen, ... Drug discovery today 17 (21-22), 1188-1198, 2012 | 288 | 2012 |
| Internal repeats in the BRCA2 protein sequence P Bork, N Blomberg, M Nilges Nature genetics 13 (1), 22-23, 1996 | 219 | 1996 |
| The PH superfold: a structural scaffold for multiple functions N Blomberg, E Baraldi, M Nilges, M Saraste Trends in biochemical sciences 24 (11), 441-445, 1999 | 200 | 1999 |
| Making sense of big data in health research: towards an EU action plan C Auffray, R Balling, I Barroso, L Bencze, M Benson, J Bergeron, ... Genome medicine 8 (1), 71, 2016 | 149 | 2016 |
| An integrated approach to fragment-based lead generation: philosophy, strategy and case studies from AstraZeneca's drug discovery programmes JS Albert, N Blomberg, AL Breeze, AJH Brown, JN Burrows, PD Edwards, ... Current topics in medicinal chemistry 7 (16), 1600-1629, 2007 | 127 | 2007 |
| A new approach for applying residual dipolar couplings as restraints in structure elucidation J Meiler, N Blomberg, M Nilges, C Griesinger Journal of biomolecular NMR 16 (3), 245-252, 2000 | 118 | 2000 |
| ’t Hoen PAC MD Wilkinson, M Dumontier, IJ Aalbersberg, G Appleton, M Axton, A Baak, ... Hooft R, Kuhn T, Kok R, Kok J, Lusher SJ, Martone ME, Mons A, Packer AL …, 2016 | 105 | 2016 |
| Development, interpretation and temporal evaluation of a global QSAR of hERG electrophysiology screening data CL Gavaghan, CH Arnby, N Blomberg, G Strandlund, S Boyer Journal of computer-aided molecular design 21 (4), 189-206, 2007 | 105 | 2007 |
| Classification of protein sequences by homology modeling and quantitative analysis of electrostatic similarity N Blomberg, RR Gabdoulline, M Nilges, RC Wade Proteins: Structure, Function, and Bioinformatics 37 (3), 379-387, 1999 | 105 | 1999 |
| Design of compound libraries for fragment screening N Blomberg, DA Cosgrove, PW Kenny, K Kolmodin Journal of computer-aided molecular design 23 (8), 513-525, 2009 | 80 | 2009 |
| Total synthesis and structural confirmation of chlorodysinosin A S Hanessian, JR Del Valle, Y Xue, N Blomberg Journal of the American Chemical Society 128 (32), 10491-10495, 2006 | 73 | 2006 |
| Multifingerprint based similarity searches for targeted class compound selection T Kogej, O Engkvist, N Blomberg, S Muresan Journal of chemical information and modeling 46 (3), 1201-1213, 2006 | 62 | 2006 |
| Big pharma screening collections: more of the same or unique libraries? The AstraZeneca–Bayer Pharma AG case T Kogej, N Blomberg, PJ Greasley, S Mundt, MJ Vainio, J Schamberger, ... Drug discovery today 18 (19-20), 1014-1024, 2013 | 58 | 2013 |
| Identifiers for the 21st century: How to design, provision, and reuse persistent identifiers to maximize utility and impact of life science data JA McMurry, N Juty, N Blomberg, T Burdett, T Conlin, N Conte, M Courtot, ... PLoS biology 15 (6), 2017 | 52 | 2017 |
| Scientific competency questions as the basis for semantically enriched open pharmacological space development K Azzaoui, E Jacoby, S Senger, EC Rodríguez, M Loza, B Zdrazil, M Pinto, ... Drug discovery today 18 (17-18), 843-852, 2013 | 52 | 2013 |
| The FAIR Guiding Principles for scientific data management and stewardship. Scientific Data, 3, 160018 MD Wilkinson, M Dumontier, IJ Aalbersberg, G Appleton, M Axton, A Baak, ... As Open as Possible, as Closed as Necessary’–Managing legal and owner 3, 2016 | 51 | 2016 |
| Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules T Luker, L Alcaraz, KK Chohan, N Blomberg, DS Brown, RJ Butlin, ... Bioorganic & medicinal chemistry letters 21 (19), 5673-5679, 2011 | 50 | 2011 |
| Functional diversity of PH domains: an exhaustive modelling study N Blomberg, M Nilges Folding and Design 2 (6), 343-355, 1997 | 45 | 1997 |
Michael NilgesInstitut PasteurVerified email at pasteur.fr
