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Holger Flechsig
Holger Flechsig
Assistant Professor, Kanazawa University
Verified email at staff.kanazawa-u.ac.jp
Title
Cited by
Cited by
Year
Tracing entire operation cycles of molecular motor hepatitis C virus helicase in structurally resolved dynamical simulations
H Flechsig, AS Mikhailov
Proceedings of the National Academy of Sciences 107 (49), 20875-20880, 2010
552010
BioAFMviewer: An interactive interface for simulated AFM scanning of biomolecular structures and dynamics
R Amyot, H Flechsig
PLoS computational biology 16 (11), e1008444, 2020
532020
Design of elastic networks with evolutionary optimized long-range communication as mechanical models of allosteric proteins
H Flechsig
Biophysical journal 113 (3), 558-571, 2017
512017
Simple mechanics of protein machines
H Flechsig, AS Mikhailov
Journal of the Royal Society Interface 16 (155), 20190244, 2019
352019
Coarse-grained protein dynamics studies using elastic network models
Y Togashi, H Flechsig
International journal of molecular sciences 19 (12), 3899, 2018
352018
An ultra-wide scanner for large-area high-speed atomic force microscopy with megapixel resolution
A Marchesi, K Umeda, T Komekawa, T Matsubara, H Flechsig, T Ando, ...
Scientific Reports 11 (1), 13003, 2021
262021
Simulation atomic force microscopy for atomic reconstruction of biomolecular structures from resolution-limited experimental images
R Amyot, A Marchesi, CM Franz, I Casuso, H Flechsig
PLoS computational biology 18 (3), e1009970, 2022
252022
Allosteric communication in molecular machines via information exchange: what can be learned from dynamical modeling
D Loutchko, H Flechsig
Biophysical reviews 12 (2), 443-452, 2020
232020
In silico investigation of conformational motions in superfamily 2 helicase proteins
H Flechsig, D Popp, AS Mikhailov
PLoS One 6 (7), e21809, 2011
212011
Designed elastic networks: Models of complex protein machinery
H Flechsig, Y Togashi
International journal of molecular sciences 19 (10), 3152, 2018
132018
Non-RVD mutations that enhance the dynamics of the TAL repeat array along the superhelical axis improve TALEN genome editing efficacy
N Tochio, K Umehara, J Uewaki, H Flechsig, M Kondo, T Dewa, ...
Scientific reports 6 (1), 37887, 2016
122016
TALEs from a Spring – Superelasticity of Tal Effector Protein Structures
H Flechsig
PLOS ONE 9 (10), e109919, 2014
112014
Novel DNA aptamer for CYP24A1 inhibition with enhanced antiproliferative activity in cancer cells
M Biyani, K Yasuda, Y Isogai, Y Okamoto, W Weilin, N Kodera, H Flechsig, ...
ACS Applied Materials & Interfaces 14 (16), 18064-18078, 2022
102022
Nucleotide-induced conformational dynamics in ABC transporters from structure-based coarse grained modeling
H Flechsig
Frontiers in Physics 4, 3, 2016
102016
Protein dynamics by the combination of high-speed AFM and computational modeling
H Flechsig, T Ando
Current Opinion in Structural Biology 80, 102591, 2023
92023
Deciphering intrinsic inter-subunit couplings that lead to sequential hydrolysis of F1-ATPase ring
L Dai, H Flechsig, J Yu
Biophysical journal 113 (7), 1440-1453, 2017
92017
Towards synthetic molecular motors: a model elastic-network study
A Sarkar, H Flechsig, AS Mikhailov
New Journal of Physics 18 (4), 043006, 2016
92016
Computational biology approach to uncover hepatitis C virus helicase operation
H Flechsig
World journal of gastroenterology: WJG 20 (13), 3401, 2014
72014
Imaging single CaMKII holoenzymes at work by high-speed atomic force microscopy
S Tsujioka, A Sumino, Y Nagasawa, T Sumikama, H Flechsig, L Puppulin, ...
Science Advances 9 (26), eadh1069, 2023
52023
BioAFMviewer software for simulation atomic force microscopy of molecular structures and conformational dynamics
R Amyot, N Kodera, H Flechsig
Journal of Structural Biology: X 7, 100086, 2023
42023
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