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Rilei Yu
Rilei Yu
Unknown affiliation
Verified email at bioch.ox.ac.uk
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Year
ConoServer: updated content, knowledge, and discovery tools in the conopeptide database
Q Kaas, R Yu, AH Jin, S Dutertre, DJ Craik
Nucleic acids research 40 (D1), D325-D330, 2012
3892012
Pathophysiology of obesity and its associated diseases
X Jin, T Qiu, L Li, R Yu, X Chen, C Li, CG Proud, T Jiang
Acta Pharmaceutica Sinica B 13 (6), 2403-2424, 2023
1752023
SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells
Y Tong, D Guo, SH Lin, J Liang, D Yang, C Ma, F Shao, M Li, Q Yu, ...
Molecular Cell 81 (11), 2303-2316. e8, 2021
1162021
Determination of the α-conotoxin Vc1. 1 binding site on the α9α10 nicotinic acetylcholine receptor
R Yu, SN Kompella, DJ Adams, DJ Craik, Q Kaas
Journal of medicinal chemistry 56 (9), 3557-3567, 2013
1042013
Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets
R Liu, JH Lee, J Li, R Yu, L Tan, Y Xia, Y Zheng, XL Bian, PL Lorenzi, ...
Molecular cell 81 (13), 2722-2735. e9, 2021
862021
Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations
R Yu, DJ Craik, Q Kaas
PLoS computational biology 7 (3), e1002011, 2011
862011
Less is more: design of a highly stable disulfide-deleted mutant of analgesic cyclic α-conotoxin Vc1. 1
R Yu, VAL Seymour, G Berecki, X Jia, M Akcan, DJ Adams, Q Kaas, ...
Scientific reports 5 (1), 13264, 2015
572015
Pharmacokinetics in Vitro and in Vivo of Two Novel Prodrugs of Oleanolic Acid in Rats and Its Hepatoprotective Effects against Liver Injury Induced by CCl4
Z Yu, W Sun, W Peng, R Yu, G Li, T Jiang
Molecular Pharmaceutics 13 (5), 1699-1710, 2016
552016
Novel natural angiotensin converting enzyme (ACE)-inhibitory peptides derived from sea cucumber-modified hydrolysates by adding exogenous proline and a study of their structure …
J Li, Z Liu, Y Zhao, X Zhu, R Yu, S Dong, H Wu
Marine Drugs 16 (8), 271, 2018
502018
Agonist and antagonist binding in human glycine receptors
R Yu, E Hurdiss, T Greiner, R Lape, L Sivilotti, PC Biggin
Biochemistry 53 (38), 6041-6051, 2014
462014
Medicinal chemistry, pharmacology, and therapeutic potential of α-conotoxins antagonizing the α9α10 nicotinic acetylcholine receptor
X Li, HS Tae, Y Chu, T Jiang, DJ Adams, R Yu
Pharmacology & Therapeutics 222, 107792, 2021
422021
Cyclic analogues of α‐conotoxin Vc1. 1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain
J Castro, L Grundy, A Deiteren, AM Harrington, T O'Donnell, J Maddern, ...
British journal of pharmacology 175 (12), 2384-2398, 2018
412018
Progress in developing MNK inhibitors
X Jin, R Yu, X Wang, CG Proud, T Jiang
European Journal of Medicinal Chemistry 219, 113420, 2021
382021
Designing antimicrobial peptides using deep learning and molecular dynamic simulations
Q Cao, C Ge, X Wang, PJ Harvey, Z Zhang, Y Ma, X Wang, X Jia, M Mobli, ...
Briefings in Bioinformatics 24 (2), bbad058, 2023
372023
Application of reverse docking for target prediction of marine compounds with anti-tumor activity
F Chen, Z Wang, C Wang, Q Xu, J Liang, X Xu, J Yang, C Wang, T Jiang, ...
Journal of Molecular Graphics and Modelling 77, 372-377, 2017
362017
Discovery of DNA topoisomerase I inhibitors with low-cytotoxicity based on virtual screening from natural products
LT Xin, L Liu, CL Shao, RL Yu, FL Chen, SJ Yue, M Wang, ZL Guo, ...
Marine drugs 15 (7), 217, 2017
362017
Boronic acid modifications enhance the anti-influenza A virus activities of novel quindoline derivatives
W Wang, R Yin, M Zhang, R Yu, C Hao, L Zhang, T Jiang
Journal of Medicinal Chemistry 60 (7), 2840-2852, 2017
362017
Delineation of the unbinding pathway of α-conotoxin ImI from the α7 nicotinic acetylcholine receptor
R Yu, Q Kaas, DJ Craik
The Journal of Physical Chemistry B 116 (21), 6097-6105, 2012
362012
Design, synthesis and activity of Mnk1 and Mnk2 selective inhibitors containing thieno [2, 3-d] pyrimidine scaffold
X Jin, J Merrett, S Tong, B Flower, J Xie, R Yu, S Tian, L Gao, J Zhao, ...
European journal of medicinal chemistry 162, 735-751, 2019
342019
Design of SARS-CoV-2 Mpro, PLpro dual-target inhibitors based on deep reinforcement learning and virtual screening
L Zhang, H Zhao, J Liu, L He, R Yu, C Kang
Future Medicinal Chemistry 14 (6), 393-405, 2022
322022
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