Rilei Yu
Rilei Yu
Unknown affiliation
Verified email at bioch.ox.ac.uk
TitleCited byYear
ConoServer: updated content, knowledge, and discovery tools in the conopeptide database
Q Kaas, R Yu, AH Jin, S Dutertre, DJ Craik
Nucleic acids research 40 (D1), D325-D330, 2011
2312011
Determination of the α-conotoxin Vc1. 1 binding site on the α9α10 nicotinic acetylcholine receptor
R Yu, SN Kompella, DJ Adams, DJ Craik, Q Kaas
Journal of medicinal chemistry 56 (9), 3557-3567, 2013
632013
Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations
R Yu, DJ Craik, Q Kaas
PLoS computational biology 7 (3), e1002011, 2011
632011
Agonist and antagonist binding in human glycine receptors
R Yu, E Hurdiss, T Greiner, R Lape, L Sivilotti, PC Biggin
Biochemistry 53 (38), 6041-6051, 2014
362014
Less is More: Design of a highly stable disulfide-deleted mutant of analgesic cyclic α-conotoxin Vc1. 1
R Yu, VAL Seymour, G Berecki, X Jia, M Akcan, DJ Adams, Q Kaas, ...
Scientific reports 5, 13264, 2015
302015
Delineation of the unbinding pathway of α-conotoxin ImI from the α7 nicotinic acetylcholine receptor
R Yu, Q Kaas, DJ Craik
The Journal of Physical Chemistry B 116 (21), 6097-6105, 2012
262012
Boronic acid modifications enhance the anti-influenza A virus activities of novel quindoline derivatives
W Wang, R Yin, M Zhang, R Yu, C Hao, L Zhang, T Jiang
Journal of medicinal chemistry 60 (7), 2840-2852, 2017
152017
Pharmacokinetics in vitro and in vivo of two novel prodrugs of oleanolic acid in rats and its hepatoprotective effects against liver injury induced by CCl4
Z Yu, W Sun, W Peng, R Yu, G Li, T Jiang
Molecular pharmaceutics 13 (5), 1699-1710, 2016
152016
2‐Pyridinyl‐4 (3H)‐Quinazolinone: A Scaffold for Anti‐influenza A Virus Compounds
S Liu, W Wang, L Jiang, S Wan, L Zhang, R Yu, T Jiang
Chemical biology & drug design 86 (5), 1221-1225, 2015
142015
Isothiouronium modification empowers pyrimidine-substituted curcumin analogs potent cytotoxicity and Golgi localization
S Tong, M Zhang, S Wang, R Yin, R Yu, S Wan, T Jiang, L Zhang
European journal of medicinal chemistry 123, 849-857, 2016
132016
Investigation of α-conotoxin unbinding using umbrella sampling
R Yu, N Tabassum, T Jiang
Bioorganic & medicinal chemistry letters 26 (4), 1296-1300, 2016
132016
Cyclic analogues of α‐conotoxin Vc1. 1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain
J Castro, L Grundy, A Deiteren, AM Harrington, T O'Donnell, J Maddern, ...
British journal of pharmacology 175 (12), 2384-2398, 2018
122018
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors
R Zhang, R Yu, Q Xu, X Li, J Luo, B Jiang, L Wang, S Guo, N Wu, D Shi
European journal of medicinal chemistry 134, 24-33, 2017
102017
Discovery of DNA topoisomerase I inhibitors with low-cytotoxicity based on virtual screening from natural products
LT Xin, L Liu, CL Shao, RL Yu, FL Chen, SJ Yue, M Wang, ZL Guo, ...
Marine drugs 15 (7), 217, 2017
102017
Dual-inhibitors of STAT5 and STAT3: studies from molecular docking and molecular dynamics simulations
S Shao, R Yu, Y Yu, Y Li
Journal of molecular modeling 20 (8), 2399, 2014
102014
Determination of the μ-Conotoxin PIIIA Specificity Against Voltage-Gated Sodium Channels from Binding Energy Calculations
F Chen, W Huang, T Jiang, R Yu
Marine drugs 16 (5), 153, 2018
92018
Partial activation of α7 nicotinic acetylcholine receptors: insights from molecular dynamics simulations
C Shi, R Yu, S Shao, Y Li
Journal of molecular modeling 19 (2), 871-878, 2013
92013
α‐Conotoxins active at α3‐containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition
H Cuny, R Yu, HS Tae, SN Kompella, DJ Adams
British journal of pharmacology 175 (11), 1855-1868, 2018
82018
Key structural determinants in the agonist binding loops of human β2 and β4 nicotinic acetylcholine receptor subunits contribute to α3β4 subtype selectivity of α-conotoxins
H Cuny, SN Kompella, HS Tae, R Yu, DJ Adams
Journal of Biological Chemistry 291 (45), 23779-23792, 2016
82016
Application of reverse docking for target prediction of marine compounds with anti-tumor activity
F Chen, Z Wang, C Wang, Q Xu, J Liang, X Xu, J Yang, C Wang, T Jiang, ...
Journal of Molecular Graphics and Modelling 77, 372-377, 2017
72017
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