| Recon 2.2: from reconstruction to model of human metabolism N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ... Metabolomics 12, 1-7, 2016 | 309 | 2016 |
| A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ... Cell systems 3 (5), 434-443. e8, 2016 | 238 | 2016 |
| Revisiting the Evolution and Taxonomy of Clostridia, a Phylogenomic Update P Cruz-Morales, CA Orellana, G Moutafis, G Moonen, G Rincon, ... Genome Biology and Evolution 11 (7), 2035-2044, 2019 | 83 | 2019 |
| High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis CA Orellana, E Marcellin, BL Schulz, AS Nouwens, PP Gray, LK Nielsen Journal of proteome research 14 (2), 609-618, 2015 | 76 | 2015 |
| Vaccine production to protect animals against pathogenic clostridia NE Zaragoza, CA Orellana, GA Moonen, G Moutafis, E Marcellin Toxins 11 (9), 525, 2019 | 54 | 2019 |
| Attenuating apoptosis in Chinese hamster ovary cells for improved biopharmaceutical production MN Henry, MA MacDonald, CA Orellana, PP Gray, M Gillard, K Baker, ... Biotechnology and Bioengineering 117 (4), 1187-1203, 2020 | 38 | 2020 |
| Mathematical modeling of elution curves for a protein mixture in ion exchange chromatography applied to high protein concentration CA Orellana, C Shene, JA Asenjo Biotechnology and bioengineering 104 (3), 572-581, 2009 | 38 | 2009 |
| RNA‐Seq highlights high clonal variation in monoclonal antibody producing CHO cells CA Orellana, E Marcellin, RW Palfreyman, TP Munro, PP Gray, ... Biotechnology journal 13 (3), 1700231, 2018 | 36 | 2018 |
| Metabolic Reconstruction of Setaria italica: A Systems Biology Approach for Integrating Tissue-Specific Omics and Pathway Analysis of Bioenergy Grasses CG de Oliveira Dal'Molin, C Orellana, L Gebbie, J Steen, MP Hodson, ... Frontiers in plant science 7, 1138, 2016 | 36 | 2016 |
| Overexpression of the regulatory subunit of glutamate‐cysteine ligase enhances monoclonal antibody production in CHO cells CA Orellana, E Marcellin, PP Gray, LK Nielsen Biotechnology and Bioengineering 114 (8), 1825-1836, 2017 | 24 | 2017 |
| ‘Omics driven discoveries of gene targets for apoptosis attenuation in CHO cells CA Orellana, VS Martínez, MA MacDonald, MN Henry, M Gillard, PP Gray, ... Biotechnology and Bioengineering 118 (1), 481-490, 2021 | 8 | 2021 |
| Time-course transcriptomics reveals that amino acids catabolism plays a key role in toxinogenesis and morphology in Clostridium tetani CA Orellana, NE Zaragoza, C Licona-Cassani, RW Palfreyman, N Cowie, ... Journal of Industrial Microbiology & Biotechnology: Official Journal of the …, 2020 | 7 | 2020 |
| A Consensus genomescale reconstruction of Chinese hamster ovary cell metabolism. Cell Syst 3 (5): 434-443. e8 H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ... | 6 | 2016 |
| A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism. Cell Syst. 3, 434–443 e8 H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ... | 6 | 2016 |
| Recon 2.2: from reconstruction to model of human metabolism. Metabolomics 12 N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ... | 6 | 2016 |
| Multi-omics approach for comparative studies of monoclonal antibody producing CHO cells CA Orellana, E Marcellin, T Munro, PP Gary, LK Nielsen BMC Proceedings 9, 1-3, 2015 | 6 | 2015 |
| Mathematical modelling of a protein mixture in chromatography applied to high protein concentrations and optimal selection of operating conditions JA Asenjo, CA Orellana, BA Andrews Journal of bioscience and bioengineering 108, S3, 2009 | | 2009 |
| A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism M Lakshmanan, CA Orellana, D Baycin-Hizal, Y Huang, D Ley, ... | | |
| Overexpression of Gclm enhances mAb productivity in CHO cells CA Orellana, E Marcellin, R Palfreyman, P Gray, LK Nielsen | | |
