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| Substantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: results of a phase I study of navitoclax in patients with relapsed or refractory disease AW Roberts, JF Seymour, JR Brown, WG Wierda, TJ Kipps, SL Khaw, ... Journal of Clinical Oncology 30 (5), 488, 2012 | 933 | 2012 |
| Bcl-2, Bcl-xL, and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells D Mérino, SL Khaw, SP Glaser, DJ Anderson, LD Belmont, C Wong, ... Blood, The Journal of the American Society of Hematology 119 (24), 5807-5816, 2012 | 224 | 2012 |
| Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer M Wong, C Mayoh, LMS Lau, DA Khuong-Quang, M Pinese, A Kumar, ... Nature medicine 26 (11), 1742-1753, 2020 | 215 | 2020 |
| Venetoclax and navitoclax in combination with chemotherapy in patients with relapsed or refractory acute lymphoblastic leukemia and lymphoblastic lymphoma VA Pullarkat, NJ Lacayo, E Jabbour, JE Rubnitz, A Bajel, TW Laetsch, ... Cancer discovery 11 (6), 1440-1453, 2021 | 179 | 2021 |
| Venetoclax responses of pediatric ALL xenografts reveal sensitivity of MLL-rearranged leukemia SL Khaw, S Suryani, K Evans, J Richmond, A Robbins, RT Kurmasheva, ... Blood, The Journal of the American Society of Hematology 128 (10), 1382-1395, 2016 | 167 | 2016 |
| Hierarchy for targeting prosurvival BCL2 family proteins in multiple myeloma: pivotal role of MCL1 JN Gong, T Khong, D Segal, Y Yao, CD Riffkin, JM Garnier, SL Khaw, ... Blood, The Journal of the American Society of Hematology 128 (14), 1834-1844, 2016 | 151 | 2016 |
| The Bcl-2 homology domain 3 mimetic ABT-737 targets the apoptotic machinery in acute lymphoblastic leukemia resulting in synergistic in vitro and in vivo interactions with … LM High, B Szymanska, U Wilczynska-Kalak, N Barber, R O'Brien, ... Molecular pharmacology 77 (3), 483-494, 2010 | 149 | 2010 |
| VDAC2 enables BAX to mediate apoptosis and limit tumor development HS Chin, MX Li, IKL Tan, RL Ninnis, B Reljic, K Scicluna, LF Dagley, ... Nature communications 9 (1), 4976, 2018 | 123 | 2018 |
| The BH3 mimetic compound, ABT-737, synergizes with a range of cytotoxic chemotherapy agents in chronic lymphocytic leukemia KD Mason, SL Khaw, KC Rayeroux, E Chew, EF Lee, WD Fairlie, ... Leukemia 23 (11), 2034-2041, 2009 | 112 | 2009 |
| Three-year update of tisagenlecleucel in pediatric and young adult patients with relapsed/refractory acute lymphoblastic leukemia in the ELIANA trial TW Laetsch, SL Maude, S Rives, H Hiramatsu, H Bittencourt, P Bader, ... Journal of Clinical Oncology 41 (9), 1664, 2023 | 108 | 2023 |
| Both leukaemic and normal peripheral B lymphoid cells are highly sensitive to the selective pharmacological inhibition of prosurvival Bcl-2 with ABT-199 SL Khaw, D Merino, MA Anderson, SP Glaser, P Bouillet, AW Roberts, ... Leukemia 28 (6), 1207-1215, 2014 | 105 | 2014 |
| Temozolomide in pediatric low‐grade glioma SL Khaw, LT Coleman, PA Downie, JA Heath, DM Ashley Pediatric Blood & Cancer 49 (6), 808-811, 2007 | 59 | 2007 |
| The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia LM Brown, A Lonsdale, A Zhu, NM Davidson, B Schmidt, A Hawkins, ... Blood advances 4 (5), 930-942, 2020 | 58 | 2020 |
| Overcoming blocks in apoptosis with BH3-mimetic therapy in haematological malignancies SL Khaw, DCS Huang, AW Roberts Pathology-Journal of the RCPA 43 (6), 525-535, 2011 | 53 | 2011 |
| Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL–USP2 fusions C Meyer, BA Lopes, A Caye-Eude, H Cavé, C Arfeuille, W Cuccuini, ... Leukemia 33 (9), 2306-2340, 2019 | 47 | 2019 |
| Dysregulation of BCL-2 family proteins by leukemia fusion genes LM Brown, DT Hanna, SL Khaw, PG Ekert Journal of Biological Chemistry 292 (35), 14325-14333, 2017 | 36 | 2017 |
| BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and transformed hematopoietic cells Z Xu, PP Sharp, Y Yao, D Segal, CH Ang, SL Khaw, BJ Aubrey, J Gong, ... Leukemia 30 (7), 1531-1541, 2016 | 36 | 2016 |
| Cotargeting BCL-2 and MCL-1 in high-risk B-ALL DM Moujalled, DT Hanna, S Hediyeh-Zadeh, G Pomilio, L Brown, ... Blood advances 4 (12), 2762-2767, 2020 | 31 | 2020 |
| Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide SL Khaw, PA Downie, KD Waters, DM Ashley, JA Heath Pediatric Blood & Cancer 49 (3), 341-343, 2007 | 29 | 2007 |
