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Ruby Law
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An overview of the serpin superfamily
RHP Law, Q Zhang, S McGowan, AM Buckle, GA Silverman, W Wong, ...
Genome biology 7, 1-11, 2006
8552006
The structural basis for membrane binding and pore formation by lymphocyte perforin
RHP Law, N Lukoyanova, I Voskoboinik, TT Caradoc-Davies, K Baran, ...
Nature 468 (7322), 447-451, 2010
4722010
The MACPF/CDC family of pore‐forming toxins
CJ Rosado, S Kondos, TE Bull, MJ Kuiper, RHP Law, AM Buckle, ...
Cellular microbiology 10 (9), 1765-1774, 2008
3392008
A common fold mediates vertebrate defense and bacterial attack
CJ Rosado, AM Buckle, RHP Law, RE Butcher, WT Kan, CH Bird, K Ung, ...
Science 317 (5844), 1548-1551, 2007
3242007
Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack
JA Lopez, O Susanto, MR Jenkins, N Lukoyanova, VR Sutton, RHP Law, ...
Blood, The Journal of the American Society of Hematology 121 (14), 2659-2668, 2013
3152013
GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop
G Fenalti, RHP Law, AM Buckle, C Langendorf, K Tuck, CJ Rosado, ...
Nature structural & molecular biology 14 (4), 280-286, 2007
2552007
The X-ray crystal structure of full-length human plasminogen
RHP Law, T Caradoc-Davies, N Cowieson, AJ Horvath, AJ Quek, ...
Cell reports 1 (3), 185-190, 2012
2442012
New insights into the structure and function of the plasminogen/plasmin system
RHP Law, D Abu-Ssaydeh, JC Whisstock
Current opinion in structural biology 23 (6), 836-841, 2013
1742013
Conformational changes during pore formation by the perforin-related protein pleurotolysin
N Lukoyanova, SC Kondos, I Farabella, RHP Law, CF Reboul, ...
PLoS biology 13 (2), e1002049, 2015
1392015
Structure of the poly-C9 component of the complement membrane attack complex
NV Dudkina, BA Spicer, CF Reboul, PJ Conroy, N Lukoyanova, ...
Nature communications 7 (1), 10588, 2016
1252016
The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins
AJ Horvath, JA Irving, J Rossjohn, RH Law, SP Bottomley, NS Quinsey, ...
Journal of Biological Chemistry 280 (52), 43168-43178, 2005
1242005
Cloning and Expression of the Major SecretedCathepsin B-Like Protein from Juvenile Fasciola hepatica andAnalysis of Immunogenicity following Liver FlukeInfection
RHP Law, PM Smooker, JA Irving, D Piedrafita, R Ponting, NJ Kennedy, ...
Infection and immunity 71 (12), 6921-6932, 2003
1202003
X-ray crystal structure of the streptococcal specific phage lysin PlyC
S McGowan, AM Buckle, MS Mitchell, JT Hoopes, DT Gallagher, ...
Proceedings of the National Academy of Sciences 109 (31), 12752-12757, 2012
1192012
The structure and function of mammalian membrane‐attack complex/perforin‐like proteins
SC Kondos, T Hatfaludi, I Voskoboinik, JA Trapani, RHP Law, ...
Tissue Antigens 76 (5), 341-351, 2010
1032010
The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates
RM Kennan, W Wong, OP Dhungyel, X Han, D Wong, D Parker, ...
PLoS pathogens 6 (11), e1001210, 2010
952010
The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix
RHP Law, JA Irving, AM Buckle, K Ruzyla, M Buzza, ...
Journal of Biological Chemistry 280 (23), 22356-22364, 2005
882005
[10] ATP synthase from Saccharomyces cerevisiae
RHP Law, S Manon, RJ Devenish, P Nagley
Methods in Enzymology 260, 133-163, 1995
751995
A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile …
SA Beckham, D Piedrafita, CI Phillips, N Samarawickrema, RHP Law, ...
The international journal of biochemistry & cell biology 41 (7), 1601-1612, 2009
672009
The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1
SS Pang, C Bayly-Jones, M Radjainia, BA Spicer, RHP Law, AW Hodel, ...
Nature communications 10 (1), 4288, 2019
632019
Inhibition of a K9/K36 demethylase by an H3. 3 point mutation found in paediatric glioblastoma
HPJ Voon, M Udugama, W Lin, L Hii, RHP Law, DL Steer, PP Das, ...
Nature communications 9 (1), 3142, 2018
612018
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